Bovine ceroid-lipofuscinosis: pathology of blindness     

Jolly RD  Gibson AJ  Healy PJ  Slack PM  Birtles MJ 《New Zealand veterinary journal》1992,40(3):107-111

Five Devon cattle with suspected ceroid-lipofuscinosis and aged between 19 and 39 months of age were humanely slaughtered and subjected to post-mortem examination. There was severe atrophy of the cerebrum, particularly of the occipital cortex. Microscopy also showed severe atrophy of the retina with complete loss of photoreceptor cells, even in the youngest animal examined. Histopathologically the disease was characterised by accumulation of a fluorescent lipopigment in neurones, including those of the retina and a severe astrocytosis. The disease, which is characterised by the accumulation of subunit c of mitochondrial ATP synthase, is similar to that extensively described in South Hampshire sheep except that the retinal lesions were more severe. In contrast, tremors were not noted in the cattle. The clinical history and similarity to the disease in sheep and other species indicated inheritance was as an autosomal recessive trait.  相似文献   

Avian influenza jumps species in Indonesia     

Mark Thornley 《Australian veterinary journal》2005,83(8):452-452

  相似文献   

Topical treatments not just skin deep     

Mark Thornley 《Australian veterinary journal》2005,83(9):526-526

  相似文献   

Effects of sub-minimum inhibitory concentration antibiotic levels and temperature on growth kinetics and outer membrane protein expression in Mannheimia haemolytica and Haemophilus somnus          下载免费PDF全文

Brenda Y. Reeks  Franklin R. Champlin  Daniel B. Paulsen  Daniel W. Scruggs    Mark L. Lawrence 《Canadian journal of veterinary research》2005,69(1):1-10

The objective of this study was to determine the effects of sub-minimum inhibitory concentrations (sub-MICs) of 2 veterinary antibiotic preparations, chlortetracycline (CTC) and chlortetracycline-sulfamethazine (CTC + SMZ), on growth kinetics and outer membrane protein expression in Mannheimia haemolytica and Haemophilus somnus at normal and febrile body temperatures. Sub-minimum inhibitory concentrations of both antibiotics reduced the growth rates of M. haemolytica and H. somnus. Growth of both species was not inhibited when grown at 41 degrees C compared to 37 degrees C. There was no detectable consistent effect of antibiotic or temperature on outer membrane protein expression for either species. Our study indicates that sub-MIC levels of CTC and CTC + SMZ markedly impair growth of clinical M. haemolytica and H. somnus isolates, potentially allowing more effective host clearance during infection.  相似文献   

The Use of Population Viability Analyses in Conser-vation Planning. In: Per Sjögren-Gulve and Tobjörn Ebenhardv use of novel dichotomy that is of particular interest to the landscape ecologist: whether the PVA is spatially     

Schwartz  Mark 《Landscape Ecology》2002,17(2):189-190

  相似文献   

Quantifying patch distribution at multiple spatial scales: Applications to wildlife-habitat models     

Johnson  Chris J.  Boyce  Mark S.  Mulders  Robert  Gunn  Anne  Gau  Rob J.  Cluff  H. Dean  Case  Ray L. 《Landscape Ecology》2004,19(8):869-882

Multiscale analyses are widely employed for wildlife-habitat studies. In most cases, however, each scale is considered discrete and little emphasis is placed on incorporating or measuring the responses of wildlife to resources across multiple scales. We modeled the responses of three Arctic wildlife species to vegetative resources distributed at two spatial scales: patches and collections of patches aggregated across a regional area. We defined a patch as a single or homogeneous collection of pixels representing 1 of 10 unique vegetation types. We employed a spatial pattern technique, three-term local quadrat variance, to quantify the distribution of patches at a larger regional scale. We used the distance at which the variance for each of 10 vegetation types peaked to define a moving window for calculating the density of patches. When measures of vegetation patch and density were applied to resource selection functions, the most parsimonious models for wolves and grizzly bears included covariates recorded at both scales. Seasonal resource selection by caribou was best described using a model consisting of only regional scale covariates. Our results suggest that for some species and environments simple patch-scale models may not capture the full range of spatial variation in resources to which wildlife may respond. For mobile animals that range across heterogeneous areas we recommend selection models that integrate resources occurring at a number of spatial scales. Patch density is a simple technique for representing such higher-order spatial patterns.  相似文献   

Advances in echocardiography.     

Mark A Oyama 《Veterinary Clinics of North America: Small Animal Practice》2004,34(5):1083-104, v

Echocardiography is an exceptionally useful technique for diagnosing cardiovascular disease in small animals. It is noninvasive and provides a wealth of data concerning cardiac morphology and function. For many patients, echocardiography is the definitive diagnostic tool. A well-performed study coalesces the findings of the physical examination, electrocardiogram, and radiographs into a clearly defined diagnosis on which treatment decisions can be based. More so than other diagnostic techniques, echocardiography is highly operator dependent and relies on the proper acquisition and interpretation of results by an examiner who is familiar with the principles, capabilities, and limitations of ultrasound imaging.This article reviews the basics of echocardiography, measurement of cardiac dimensions, and assessment of cardiac function. Within these sections, emerging technologies that expand the capabilities of the echocardiographic examination are introduced.  相似文献   

IMAGING DIAGNOSIS: MAGNETIC RESONANCE IMAGING OF A CERVICAL WOODEN FOREIGN BODY IN A DOG     

Benjamin Young  DVM    Lisa Klopp  DVM  PhD    Mark Albrecht  DVM  DACVS    Susan Kraft  DVM  PhD 《Veterinary radiology & ultrasound》2004,45(6):538-541

This article describes the discovery of a chronic cervical wooden foreign body ventral to the left transverse processes of the cranial cervical spine using magnetic resonance imaging (MRI) in a dog that presented with chronic neck pain and lameness. The dog did not exhibit dysphagia or chronic draining tracts, the most common signs of the presumed cause, that of a penetrating oropharyngeal foreign body. The foreign body itself was represented on MR images as an oval straight-edged core within an inflammatory tissue reaction. The wood was slightly hyperintense on T2- and isointense on T1-weighted images relative to muscle. Surrounding this was a more conspicuous contrast-enhancing reactive tissue rim that was hyperintense on all pulse sequences. Adjacent musculature also exhibited diffuse edema and contrast enhancement that extended around the left cervical vertebral transverse processes and local intervertebral nerve roots. The foreign body was found to be a wooden stick upon surgical removal. MRI is an excellent method for visualizing the inflammatory tissue reactions associated with soft-tissue foreign bodies because of its contrast resolution and depiction of anatomy in multiple imaging planes.  相似文献   

Vet nurse puts teamwork into practice     

Mark Thornley 《Australian veterinary journal》2004,82(12):722-722

  相似文献   

Serologic and fecal markers to predict response to induction therapy in dogs with idiopathic inflammatory bowel disease          下载免费PDF全文

Cristiane C. Otoni  Romy M. Heilmann  Mercedes García‐Sancho  Angel Sainz  Mark R. Ackermann  Jan S. Suchodolski  Jörg M. Steiner  Albert E. Jergens 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2018,32(3):999-1008

  相似文献