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Alana Batista dos Santos Mara Lúcia Albuquerque Pereira Herymá Giovane de Oliveira Silva Gleidson Giordano Pinto de Carvalho Taiala Cristina de Jesus Pereira Leandro Sampaio Oliveira Ribeiro José Augusto Gomes Azevêdo Maria das Graças Conceição Parada Costa Silva Larisse Borges Sousa Leandro Borges Sousa Daiane de Oliveira Alencar 《Tropical animal health and production》2016,48(3):509-515
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Long‐term follow‐up of renal function assessing serum cystatin C in dogs with diabetes mellitus or hyperadrenocorticism 下载免费PDF全文
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Symmetrical alopecia, scaling and hepatitis in a rabbit 总被引:2,自引:1,他引:1
A 5-year-old rabbit with inappetence, symmetrical alopecia and skin lesions was examined. No mites or Malassezia were found in skin scrapings and tape impressions and dermatophyte culture was negative. Trial therapy with ivermectin did not reduce skin lesion severity, and euthanasia was performed because of anorexia after 1 month. Histopathology of the skin showed hyperkeratosis, lymphocytic exocytosis, cell-poor interface dermatitis (lymphocytic infiltration and apoptotic cells in basal layer of epidermis), absence of sebaceous glands and lymphocytic mural folliculitis comparable to sebaceous adenitis and thymoma-associated exfoliative dermatitis previously described in rabbits. The liver exhibited an interface hepatitis, comparable to autoimmune hepatitis in man. The occurrence of morphological similarities to exfoliative dermatitis and sebaceous adenitis in rabbits, in association with an autoimmune hepatitis, has not been described before. 相似文献
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Aguiar PH Barrouin-Melo SM Franke CR dos Santos RR Silva TM Mengel JO dos-Santos WL Pontes-de-Carvalho L 《Veterinary journal (London, England : 1997)》2007,173(1):158-166
This report describes the characterisation of a monoclonal antibody (mAb), AB6, which recognises specifically a cluster of canine leukocyte surface molecules. The immunogen used for obtaining the AB6 mAb was a lysate of canine peripheral blood mononuclear cells (PBMC). This novel mAb belongs to the IgG2a isotype, and reacted in Western blot with four different canine leukocyte glycoproteins with apparent molecular weights of 180, 190, 205 and 220 kDa. The AB6 mAb recognised the majority of canine peripheral blood leukocytes as determined by flow cytometry (97%). It also exhibited a broad reactivity pattern against lymphoid and myeloid cells, inhibited the proliferation of mitogen-stimulated canine PBMC and did not recognise human PBMC and murine splenocytes. The biochemical properties, cell and tissue specificity, and in vitro biological activity of the AB6 mAb indicate that it recognises a canine CD45 homologue. The mAb could become a valuable diagnostic and research tool for the evaluation of immune functions in dogs. 相似文献
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A ten-year review of commercial vaccine performance for control of tick infestations on cattle 总被引:3,自引:0,他引:3
de la Fuente J Almazán C Canales M Pérez de la Lastra JM Kocan KM Willadsen P 《Animal health research reviews / Conference of Research Workers in Animal Diseases》2007,8(1):23-28
Ticks are important ectoparasites of domestic and wild animals, and tick infestations economically impact cattle production worldwide. Control of cattle tick infestations has been primarily by application of acaricides which has resulted in selection of resistant ticks and environmental pollution. Herein we discuss data from tick vaccine application in Australia, Cuba, Mexico and other Latin American countries. Commercial tick vaccines for cattle based on the Boophilus microplus Bm86 gut antigen have proven to be a feasible tick control method that offers a cost-effective, environmentally friendly alternative to the use of acaricides. Commercial tick vaccines reduced tick infestations on cattle and the intensity of acaricide usage, as well as increasing animal production and reducing transmission of some tick-borne pathogens. Although commercialization of tick vaccines has been difficult owing to previous constraints of antigen discovery, the expense of testing vaccines in cattle, and company restructuring, the success of these vaccines over the past decade has clearly demonstrated their potential as an improved method of tick control for cattle. Development of improved vaccines in the future will be greatly enhanced by new and efficient molecular technologies for antigen discovery and the urgent need for a tick control method to reduce or replace the use of acaricides, especially in regions where extensive tick resistance has occurred. 相似文献