B‐cell lymphoma with Mott cell differentiation in two young adult dogs     

Nicole I. Stacy  Mary B. Nabity  Nicole Hackendahl  Melanie Buote  Jennifer Ward  Pamela E. Ginn  William Vernau  William L. Clapp  John W. Harvey 《Veterinary clinical pathology / American Society for Veterinary Clinical Pathology》2009,38(1):113-120

Abstract: Two young adult dogs with gastrointestinal signs were each found to have an intra‐abdominal mass based on physical examination and diagnostic imaging. On exploratory laparotomy, small intestinal masses and mesenteric lymphadenopathy were found in both dogs; a liver mass was also found in dog 1. Cytologic and histologic examination of intestinal and liver masses and mesenteric lymph nodes revealed 2 distinct lymphoid cell populations: lymphoblasts and atypical Mott cells. With Romanowsky stains, the atypical Mott cells contained many discrete, clear to pale blue cytoplasmic inclusions consistent with Russell bodies that were positive by immunohistochemistry for IgM and CD79a in both dogs and for IgG in dog 2. The Mott cells and occasional lymphoblasts stained strongly positive with periodic acid‐Schiff. Using flow cytometric immunophenotyping in dog 1, 60% of peripheral blood mononuclear cells and 85% of cells in an affected lymph node were positive for CD21, CD79a, IgM, and MCH II, indicative of B‐cells. With electron microscopy, disorganized and dilated endoplasmic reticulum was seen in Mott cells in tumors from both dogs. Antigen receptor gene rearrangement analysis of lymph node and intestinal masses indicated a clonal B‐cell population. Based on cell morphology, tissue involvement, and evidence for clonal B‐cell proliferation, we diagnosed neoplasms involving Mott cells. To the authors' knowledge, this is the second report of Mott cell tumors or, more appropriately, B‐cell lymphoma with Mott cell differentiation, in dogs. More complete characterization of this neoplasm requires further investigation of additional cases. This lymphoproliferative disease should be considered as a differential diagnosis for canine gastrointestinal tumors.  相似文献   

Primary Hyperparathyroidism and Monoclonal Gammopathy in a Dog     

G. Benchekroun  A. Desmyter  A. Hidalgo  H.-J. Boulouis  E. Gomes  F. Garnier  L. Escoffier  L. Poujol  P. de Fornel-Thibaud  C. Maurey  D. Rosenberg 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2009,23(1):211-214

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Reduction of stale flavor development in low-heat skim milk powder via epicatechin addition     

Schwambach SL  Peterson DG 《Journal of agricultural and food chemistry》2006,54(2):502-508

The influence of epicatechin (EC) on off-flavor development in low-heat skim milk powder samples during processing and storage was investigated. Milk powder samples were prepared from a concentrated skim milk (control) plus a concentrated skim milk with EC (treatment). Volatile extracts of the powders were analyzed by aroma extract dilution analysis (AEDA) at 0 days and after 17 months of storage in conjunction with sensory analysis of the flavor attributes. The treatment milk powders with EC added prior to drying reported a reduction in the formation of three main compounds, 4-hydroxy-2,5-dimethyl-3-(2H)-furanone, o-aminoacetophenone, and furfural, by 8-, 4-, and 4-fold for the 0 day old samples, while for the 17 month aged samples o-aminoacetophenone was the major compound reduced in formation by 8-fold, respectively, based on the flavor dilution factors reported. The sensory evaluations indicated that the treatment milk powders for 0 day old and 17 month aged samples were statistically lower (alpha = 0.05) in stale flavor intensity in comparison to the respective control samples, while no differences were noted in bitterness intensity.  相似文献   

The influence of silvicultural treatments and site conditions on American chestnut (Castanea dentata) seedling establishment in eastern Kentucky, USA     

Chuck Rhoades  David Loftis  Jeffrey Lewis  Stacy Clark  U.S.D.A. Forest Service 《Forest Ecology and Management》2009,258(7):1211-1218

After more than 50 years of research and selective breeding, blight-resistant American chestnut (Castanea dentata) trees will soon be available for planting into the species’ pre-blight range. Increased understanding of the regeneration requirements of pure American chestnut (C. dentata [Marsh.] Borkh.) will increase the success of future efforts to establish blight-resistant chestnut. We quantified survival and initial growth of bare-root American chestnut seedlings at five locations in eastern Kentucky, USA. We used a split-plot design to compare seedlings planted within adjacent mesic and xeric sites treated with either a two-age shelterwood overstory treatment or a midstory removal treatment. The silvicultural treatments and topographic settings allowed us to evaluate chestnut seedling performance under four light and site productivity combinations. Seedling survival was 57% and seedling height averaged 94 cm following two growing seasons. Seedling survival was negatively related to sand and coarse fragment content, but was unrelated to silviculture treatment or topographic position. Chestnut seedlings grew best in shelterwood overstory treatments areas on mesic sites. Seedlings growing in shelterwood overstory treatment areas added 3- and 3.5-times more height and stem increment compared to seedlings planted after midstory removal. Seedling leaf mass and foliar nitrogen (N) content were also greatest in shelterwood plantings on mesic sites. The high-light environment created by shelterwood overstory removal resulted in better initial seedling growth, but the moderate-light of the midstory removal treatment may ultimately provide chestnut seedlings a greater advantage over competing vegetation.  相似文献   

The analgesic and sedative effects of GV20 pharmacopuncture with low-dose hydromorphone in healthy dogs undergoing ovariohysterectomy     

Elizabeth M. Scallan  Stacy L. Eckman  Caleb D. Coursey  Kristine C. Ikels  Bradley T. Simon 《The Canadian veterinary journal. La revue veterinaire canadienne》2021,62(10):1104

This study evaluates the analgesic efficacy of low-dose hydromorphone administered via pharmacopuncture at Governing Vessel 20 (GV20) for postoperative pain management following canine ovariohysterectomy. Fifty clinically healthy female dogs undergoing ovariohysterectomy were allocated to receive hydromorphone [0.1 mg/kg body weight (BW)] intramuscularly (IM, n = 25) or hydromorphone (0.01 mg/kg BW) pharmacopuncture at GV20 (GV, n = 25) following extubation. This was a prospective, blinded, randomized clinical trial. Pain and sedation scores were evaluated using the Glasgow Composite Measure Pain Scale Short Form (CMPS-SF) at 1, 2, 3, 4, and 12 hours following study treatment. Time of treatment failure (CMPS-SF ≥ 6/24) was recorded and analyzed using Kaplan-Meier survival analysis. Patient demographics and duration of surgery and anesthesia were analyzed using the appropriate unpaired Student’s t-test. The Glasgow CMPS-SF and sedation score were analyzed using a repeated measures 2-way analysis of variance (ANOVA) followed by Bonferroni post-test where appropriate. Significance was set a P < 0.05. There were no significant differences in patient demographics, anesthesia and surgery duration, and study treatment failure. The Glasgow CMPS-SF scores were significantly higher for IM compared with GV [2 (0 to 8) versus 1 (0 to 6), respectively; P = 0.044] at 4 hours. Sedation scores were significantly higher for IM compared with GV at 2 [2 (1 to 3) and 1 (1 to 3), respectively; P = 0.0004] and 4 [1 (1 to 3) and 1 (1 to 2), respectively; P = 0.03] hours. Pharmacopuncture with low-dose hydromorphone provided adequate postoperative analgesia in dogs undergoing ovariohysterectomy with reduced sedative effects. Pharmacopuncture is a good alternative in dogs when reduced dosing of opioids is recommended.  相似文献   

Whip-like heterophil projections in consecutive blood films from an injured gopher tortoise (Gopherus polyphemus) with systemic inflammation     

N. I. Stacy  D. V. Fredholm  C. Rodriguez  L. Castro  J. W. Harvey 《The Veterinary quarterly》2017,37(1):162-165

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Fishing for data in the Ross Sea     

Blight LK  Ainley DG  Ackley SF  Ballard G  Ballerini T  Brownell RL  Cheng CH  Chiantore M  Costa D  Coulter MC  Dayton P  Devries AL  Dunbar R  Earle S  Eastman JT  Emslie SD  Evans CW  Garrott RA  Kim S  Kooyman G  Lescroël A  Lizotte M  Massaro M  Olmastroni S  Ponganis PJ  Russell J  Siniff DB  Smith WO  Stewart BS  Stirling I  Willis J  Wilson P  Woehler EJ 《Science (New York, N.Y.)》2010,330(6009):1316

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Infiltrative lymphocytic mural folliculitis: a histopathological reaction pattern in skin-biopsy specimens from cats with allergic skin disease     

Andrew S. Rosenberg  Danny W. Scott  Hollis N. Erb  Sean P. McDonough 《Journal of Feline Medicine and Surgery》2010,12(2):80-85

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Rapid sedimentological and biological assessment of hydrocarbon contaminated sediments     

Robert J. Diaz  Lars Johan Hansson  Rutger Rosenberg  Paul C. Gapcynski  Michael A. Unger 《Water, air, and soil pollution》1993,66(3-4):251-266

It is possible to rapidly detect the presence of high concentrations of sediment associated hydrocarbons using a sediment profile camera and simultaneously evaluate the general sedimentological and biological character of a contaminated area. In sediments that were heavily contaminated with hydrocarbons from spills and chronic long-term additions the presence of hydrocarbons was seen about 50% of the time in the sediment profile images as unique features, ‘H spots’. The presence of these features was related to the concentration of hydrocarbons in the sediment. In highly contaminated muddy sediments ‘H spots’ were found in images collected at stations that had from 270 to 610 ppt total hydrocarbons. Sedimentological and biological information obtained from the sediment profile images confirmed the impacted nature of Elizabeth River sediments. Sediment profile imaging provide a means of obtaining an overall evaluation of the quality of a habitat and impacts on that habitat from pollution related environmental disturbances. While qualitative, an advantage of sediment profile image data is that they can be evaluated in less than a day and used to quickly locate inclusions of hydrocarbons in the sediments for further quantitative chemical or biological sampling, or mapping of heavily contaminated areas.  相似文献   

Factors influencing the abundance of three common nearshore fishes in south‐west Lake Michigan     

William L. Stacy‐Duffy  Sara M. Thomas  David H. Wahl  Sergiusz J. Czesny 《Fisheries Management and Ecology》2020,27(4):303-313

Variation in the distribution and abundance of nearshore fishes is critical to understand food web processes and fishery management issues in Lake Michigan. This study characterised patterns in abundance of three common nearshore species, yellow perch Perca flavescens (Mitchell), round goby Neogobius melanostomus (Pallas) and alewife Alosa pseudoharengus (Wilson), in relation to spatio‐temporal, abiotic and biotic factors using gillnet sampling conducted across 5 years at multiple locations representing different substrates. Significant variations were observed in alewife and round goby catches between locations. A negative relationship between round goby and age‐0 yellow perch catch was observed, indicating potential competition between the two species. This study demonstrates that variability in nearshore fish communities can be driven by factors including substrate and interspecific interactions. Given the prominent role these species play in Lake Michigan's food web and thus their importance to fishery production, a thorough understanding of these factors is warranted.  相似文献