Excess iodide and the accumulation of 125i by the thyroid,plasma and developing oocytes of the Japanese quail 1     

G. A. Robinson  D. Carol Wasnidge  F. Floto  Suzanne E. Downie 《British poultry science》1977,18(2):151-157

1. Developing oocytes of the Japanese quail accumulated 0.lb44 μg of each 1 μg of 125I‐labelled iodide after intra‐muscular injection of doses up to 500 μg iodide as Nal but only 0.lb007 μg after injection of more than this: the abrupt change in the rate of accumulation was attributed to saturation of the iodide transport mechanism.

2. The proportion of available iodide transferred into the oocytes appeared to be more dependent on the amount of iodide injected and the total weight of growing oocytes than on a requirement for either a store of iodide for the embryo or an iodide excretory pathway for the hen.

3. The thyroid was about four times more active in accumulating iodide than the oocyte.

4. The percentage of iodide accumulated by the plasma was the same at all dose rates.  相似文献   

HOW DOES YOUR PRACTICE MEASURE UP?: Looking at the CVMA National Benchmarking Program (4 in a Series)          下载免费PDF全文

Suzanne Lavictoire 《The Canadian veterinary journal. La revue veterinaire canadienne》2003,44(7):556

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IMPORTANT NOTICE TO VETERINARIANS — MICROCHIPS FOR COMPANION ANIMALS          下载免费PDF全文

Suzanne Lavictoire 《The Canadian veterinary journal. La revue veterinaire canadienne》2003,44(11):874

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HOW DOES YOUR PRACTICE MEASURE UP?: Looking at the CVMA National Benchmarking Program (6 in a Series)          下载免费PDF全文

Suzanne Lavictoire 《The Canadian veterinary journal. La revue veterinaire canadienne》2003,44(9):720

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The Effect of Temperature on Feed Consumption and Nutrient Absorption in Procambarus clarkii and Procambarus zonangulus     

Suzanne L.  Croll Stephen A.  Watts 《Journal of the World Aquaculture Society》2004,35(4):478-488

Feeding characteristics of acclimated red swamp crayfish Procambarus clarkii and white river crayfish Procambarus zonangulus were determined at 8, 14, 20, 26, and 32 C. Food consumption rates of crayfish were directly related to temperature. Feeding was minimal at 8 C. At 14 CP. zonangulus consumed significantly more feed (5.5% body weight (BW/d) than P. clarkii (1.8% BW/d). At 32 C P. clarkii consumed significantly more feed (23% BW/d) than P. zonangulus (10% BW /d), reflecting species-specific thermal optimums for feeding. Differences in food consumption rates correspond to differences in the geographical distributions of these two species. Dry matter absorption rates ranged from 55% to 75% for both species without significant temperature effect. Patterns of protein and carbohydrate absorption were similar in P. clarkii and P. zonangulus. Protein absorption efficiency decreased from 45% to 10% as temperature increased from 8 C to 32 C. The total amount of protein absorbed increased seven- to ten-fold as temperature increased. Soluble carbohydrate absorption efficiency was reduced at low temperatures. However, absorption efficiency increased approximately five-fold as temperature increased from 14 C to 20 C, but did not change substantially as temperature was increased to 32 C. The total amount of carbohydrate absorbed increased approximately 15- to 26-fold as temperature increased. The protein to carbohydrate utilization ratio was similar between species, but varied dramatically with temperature. Both species absorbed between 2.5 and four-times more protein than carbohydrate at low temperatures (8 C and 14 C). At 32 C both species utilized approximately three times more carbohydrate than protein. In spite of reduced consumption at lower temperatures, crayfish absorbed a greater protein portion. At these low temperatures it appears that crayfish maximize the efficiency of protein absorption, presumably for maintenance and growth requirements. At high temperatures it appears that crayfish maximize energy intake, presumably to sustain higher metabolic rates due to increased activity levels. These apparent temperature-dependent nutrient requirements may influence natural foraging strategies or, for species in aquaculture, the effectiveness of commercial feed preparations. At high temperatures P. clarkii was more effective in consuming nutrients than P. zonangulus and may be more successful than P. zonangulus at these temperatures.  相似文献   

ISOLATES TYPED BY THE SALMONELLA REFERENCE LABORATORY AND THE ESCHERICHIA COLI SEROTYPING LABORATORY DURING 1975     

Suzanne F. DIXON B.Sc.  A.A.I.F.S.T. 《Australian veterinary journal》1976,52(11):545-545

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Palliative intracavitary carboplatin therapy in a cat with suspected pleural mesothelioma     

Sparkes A  Murphy S  McConnell F  Smith K  Blunden AS  Papasouliotis K  Vanthournout D 《Journal of Feline Medicine and Surgery》2005,7(5):313-316

A 12-year-old neutered male oriental shorthair cat was referred to the Animal Health Trust for investigation of pleural effusion. Ultrasonography revealed marked irregular thickening of the pleural surface of the cranial and caudal mediastinum. Cytological examination of the pleural fluid and fine needle aspirates of the thickened pleura suggested a diagnosis of mesothelioma. Following complete drainage of the thoracic cavity under ultrasound guidance, 180 mg/m2 carboplatin diluted in 60 ml sterile water was infused into the pleural space (30 ml in each hemithorax). This resulted in complete resolution of clinical signs for 34 days (having required thoracocentesis on four occasions in the preceding 4 weeks). The procedure was repeated using 200 mg/m2 carboplatin, and there was a further 20-day period where the cat was free of clinical signs. Further treatment was declined and the cat was euthanased 120 days after initial presentation. This is the first report of successful palliative chemotherapy for suspected feline mesothelioma and suggests that intracavitary carboplatin could be considered in tumours affecting the pleural cavity.  相似文献   

Isolation and characterization of Babesia pecorum sp. nov. from farmed red deer (Cervus elaphus)     

Maggy Jouglin  Isabel G Fernández-de-Mera  Nathalie de la Cotte  Francisco Ruiz-Fons  Christian Gortázar  Emmanuelle Moreau  Suzanne Bastian  José de la Fuente  Laurence Malandrin 《Veterinary research》2014,45(1)

The diversity of Babesia species infecting cervids in parts of central and southern Spain was analyzed by collecting blood from farmed red deer (Cervus elaphus). Babesia sp. was isolated in vitro from two red deer herds in Cádiz and Ciudad Real. The number of Babesia sp. carriers differed between the two herds: 36/77 in Cádiz and 1/35 in Ciudad Real. Hyalomma lusitanicum was the most prevalent tick species identified on the Cádiz farm vegetation and on sampled animals, and is therefore a candidate vector. The molecular characteristics of 21 isolates were determined by complete (8 isolates) or partial (13 isolates) 18S rRNA gene sequencing. The sequences were highly similar (over 99.4% identity) and 6 sequence types were identified at the level of one herd only, demonstrating a rather high genetic diversity. They formed a monophyletic clade, and members of the three main sequence types shared a similar morphology and the same erythrocyte susceptibility pattern. This clade also included Babesia sp. Xinjiang isolated from sheep in China and Babesia sp. identified in giraffe in South Africa, with identities higher than 98.3% and statistically relevant phylogenetic support. None of the biological properties analyzed for both Babesia from red deer and Babesia sp. Xinjiang allowed their differentiation (ability to develop in vitro in erythrocytes from cattle and sheep, as well as in erythrocytes from different cervids, unsuccessful infection of calves). We propose the Babesia isolated from red deer as a new species named B. pecorum. Whether Babesia sp. Xinjiang and the Babesia characterized in South Africa belong to the same species is debated.

Electronic supplementary material

The online version of this article (doi:10.1186/s13567-014-0078-7) contains supplementary material, which is available to authorized users.  相似文献   

Lessons for farmer-oriented research: Experiences from a West African soil fertility management project     

E. Suzanne Nederlof  Constant Dangbégnon 《Agriculture and Human Values》2007,24(3):369-387

Donors, scientists and farmers all benefit when research and development projects have high impact. However, potential benefits are sometimes not realized. Our objective in this study is to determine why resource-poor farmers in Togo (declined to) adopt recommended practices that were promoted through a multi-organizational project on soil fertility management. We examine the processes and outcomes related to the adoption process. The project was undertaken in three villages in the Central Region of Togo in West Africa. The development and research processes that took place during the implementation of the project were critically analyzed using a conceptual framework that may be useful for improving the impact of future participatory projects. At the macro level, opportunities for innovation were not deliberately explored with participating farmers and other village members; consequently “pre-analytical choices” made during the planning phase resulted in practices that resource-poor farmers were, for a variety of reasons, unable or unwilling to adopt. From the outset, donors and scientists focused on soil fertility management, but failed to take into account the wider economic context within which soil fertility management took place. This was a major obstacle to the subsequent adoption of recommended management strategies. Scientists and donor partners measured the success of the Project in terms of crop productivity, but farmers’ choices were influenced by a complex mix of socio-economic, political and technical factors. We also illustrate the importance of selecting appropriate categories of farmers for a particular experiment. We conclude that for participatory research and development projects to be successful, it is not enough to develop technologies that “work” in a technical sense. In order to be scaled up and widely implemented, such technologies must also meet a variety of needs of resource-poor farmers and be acceptable from a socio-cultural point of view. Suzanne Nederlof holds a PhD in Communication and Innovation Studies from Wageningen University in the Netherlands. After finishing her MSc. degree in Development Sociology at the same university she worked at a research project in Burkina Faso and at the International Center for Soil Fertility and Agricultural Development (IFDC) in Togo. Subsequently, she was based at the FAO regional office for Africa in Ghana, assigned to the Convergence of Sciences Program. She conducted the fieldwork for this article during that period. She completed her PhD research on agricultural research with a scholarship from the Netherlands Organization for Scientific Research. She is currently employed as an advisor in rural innovation at the Royal Tropical Institute (KIT) in Amsterdam, The Netherlands. Constant Dangbégnon worked for several years (1990–1998) on Inter-University Cooperation (Benin, the Netherlands and Israel) in the area of indigenous knowledge and the soft side of natural resource management. This work constituted the basis of his PhD from Wageningen University in The Netherlands. He joined IFDC – Africa Division in Lomé (Togo) in June 1999 as a socio-economic extension specialist in the Input Accessibility Program (IAP).  相似文献   

Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes   总被引：1，自引：0，他引：1  

Dudley ME  Wunderlich JR  Robbins PF  Yang JC  Hwu P  Schwartzentruber DJ  Topalian SL  Sherry R  Restifo NP  Hubicki AM  Robinson MR  Raffeld M  Duray P  Seipp CA  Rogers-Freezer L  Morton KE  Mavroukakis SA  White DE  Rosenberg SA 《Science (New York, N.Y.)》2002,298(5594):850-854

We report here the adoptive transfer, to patients with metastatic melanoma, of highly selected tumor-reactive T cells directed against overexpressed self-derived differentiation antigens after a nonmyeloablative conditioning regimen. This approach resulted in the persistent clonal repopulation of T cells in those cancer patients, with the transferred cells proliferating in vivo, displaying functional activity, and trafficking to tumor sites. This led to regression of the patients' metastatic melanoma as well as to the onset of autoimmune melanocyte destruction. This approach presents new possibilities for the treatment of patients with cancer as well as patients with human immunodeficiency virus-related acquired immunodeficiency syndrome and other infectious diseases.  相似文献