The integration of protoplast fusion-derived material into a potato breeding programme — a review of progress and problems     

S. Millam  L. A. Payne  G. R. Mackay 《Euphytica》1995,85(1-3):451-455

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Physics. High-power fiber lasers     

Nilsson J  Payne DN 《Science (New York, N.Y.)》2011,332(6032):921-922

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Mode of Chemical-Degradation of s-Triazines by Montmorillonite     

Russell JD  Cruz M  White JL  Bailey GW  Payne WR  Pope JD  Teasley JI 《Science (New York, N.Y.)》1968,160(3834):1340-1342

Chemical hydrolysis of the s-triazines after interaction with less than 2-micron (equivalent spherical diameter) montmorillonite clay occurs as a result of protonation at the colloidal surface; protonation occurs even when the exchange sites are occupied by metallic cations. The adsorbed hydrolytic degradation product is not the hydroxy analog, but it is predominantly the keto form of the protonated hydroxy species. This cationic form is held tightly by the clay which may restrict vertical movement and entrance into groundwater. Protonation of the hydroxy analog occurs on the heterocyclic ring nitrogen.  相似文献   

Crankcase oils: are they a major mutagenic burden in the aquatic environment?     

J F Payne  I Martins  A Rahimtula 《Science (New York, N.Y.)》1978,200(4339):329-330

Fractions from used crankcase oil enriched in polyaromatic hydrocarbons induced revertant colonies in Salmonella typhimurium strain TA 98 when activated by rat or trout liver extracts. The mutagenic activity was not due to benzopyrene or benzanthracene. Fractions from various crude and refined petroleums were nonmutagenic. Among various petroleum hydrocarbons entering inland and coastal waters, used crankcase oils may represent a major mutagenic burden.  相似文献   

Protein content and specific gravity of Red McClure potatoes increased by 2,4-D treatment     

Merle G. Payne  Jess L. Fults  Ruth J. Hay  Clark H. Livingston 《American Journal of Potato Research》1953,30(2):46-49

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Control line failure in Angiostrongylus vasorum point-of-care serology test in dogs with angiostrongylosis due to suspected hook effect     

E. N. Barker  J. R. Payne  H. Wilson 《The Journal of small animal practice》2024,65(4):243-250

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Dacarbazine as Single-Agent Therapy for Relapsed Lymphoma in Dogs     

P.C. Griessmayr  S.E. Payne  J.E. Winter  L.G. Barber  F.S. Shofer 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2009,23(6):1227-1231

Background: Multidrug resistance is the most common cause of treatment failure in dogs with multicentric lymphoma. 5-(3,3-Dimethyl-1-triazeno)-imidazole-4-carboxamide (DTIC) is an atypical alkylator used as standard treatment in human Hodgkin's lymphoma, and has been effective in combination treatment to treat resistant lymphoma in dogs. However, no data are available on the use of DTIC as a single agent in the treatment of relapsed canine lymphoma.
Hypothesis: Single-agent DTIC is effective and safe in treating dogs with lymphoma that relapsed or failed to respond to previous chemotherapy.
Animals: Forty client-owned dogs with relapsed lymphoma.
Methods: Dogs were eligible for the retrospective study if they had a histologically or cytologically confirmed diagnosis of lymphoma and had relapsed. Dogs received DTIC (800–1,000 mg/m² every 2–3 weeks as a 4–5-hour IV infusion) and were evaluated for response rate and duration. Hematologic and gastrointestinal toxicity was assessed.
Results: The overall response rate for dogs being treated with DTIC was 35% (14 dogs) with a median progression-free interval of 43 days. Thirteen dogs had a partial response and 1 dog had a complete response. Stable disease was achieved in 3 dogs. Mild gastrointestinal toxicity was reported in 3 dogs posttreatment. Thrombocytopenia was the principal toxicity observed 7–14 days after the treatment. Treatments were delayed because of thrombocytopenia.
Conclusions: DTIC, when used alone, is effective in the treatment of dogs with relapsed lymphoma.  相似文献   

Antioxidant 1 copper chaperone gene expression and copper levels in dog osteosarcoma patients     

Pedro L. Rivera  William T. Li  Sumail Bhogal  Jonathan B. Mandell  Rebekah Belayneh  Margaret L. Hankins  John T. Payne  Rebecca J. Watters  Kurt R. Weiss 《Veterinary and comparative oncology》2023,21(3):559-564

Twenty-four dogs with OS underwent limb amputation. Serum, OS tumour, and normal bone were harvested at time of surgery. RNA was extracted and gene expression was performed using quantitative polymerase chain reaction (qPCR). Tissue and blood copper concentrations were also determined with spectrophotometry. Compared to bone, tumour samples had significantly higher expressions of antioxidant 1 copper chaperone (ATOX1, p = .0003). OS tumour copper levels were significantly higher than that of serum (p < .010) and bone (p = .038). Similar to our previous observations in mouse and human OS, dog OS demonstrates overexpression of genes that regulate copper metabolism (ATOX1), and subsequent copper levels. Dogs with OS may provide a robust comparative oncology platform for the further study of these factors, as well as potential pharmacologic interventions.  相似文献