剪切型超短超细钢纤维增强砂浆强度的试验研究     

王龙飞  高长成  应文宗  周超 《西南大学学报(自然科学版)》2011,33(7)

在砂浆中加入钢纤维可以显著地改善砂浆的强度,不同掺量、不同长度的钢纤维对砂浆强度的影响也不同.通过在砂浆中掺入11种不同量的剪切型超短超细钢纤维(长度:6 mm,直径:0.2 mm)和掺入6种不同量的普通钢纤维试件的强度试验并进行对比分析,得出了砂浆中掺入剪切型超短超细钢纤维砂浆后的强度规律:在钢纤维掺入量小于3%时,普通钢纤维砂浆强度略高于剪切型超短超细钢纤维砂浆;在钢纤维掺入量大于3%时,剪切型超短超细钢纤维砂浆强度明显高于普通钢纤维砂浆.  相似文献   

Morphine tolerance, physical dependence, and synthesis of brain 5-hydroxytryptamine   总被引：3，自引：0，他引：3  

E L Way  H H Loh  F Shen 《Science (New York, N.Y.)》1968,162(859):1290-1292

Tolerance and physical dependence development to morphine in mice can be prevented by concomitant administration of cycloheximide. The fact that the rate of synthesis of brain 5-hydroxytryptamine (5HT) increases with tolerance to morphine suggests that the protein involved may be associated with 5HT synthesis. Inhibition of this synthesis with p-chlorophenylalanine markedly decreases tolerance and physical dependence development to morphine.  相似文献   

Growth suppression of HER2-overexpressing breast cancer cells by berberine via modulation of the HER2/PI3K/Akt signaling pathway     

Kuo HP  Chuang TC  Yeh MH  Hsu SC  Way TD  Chen PY  Wang SS  Chang YH  Kao MC  Liu JY 《Journal of agricultural and food chemistry》2011,59(15):8216-8224

Berberine (BBR) is a natural alkaloid with significant antitumor activities against many types of cancer cells. This study investigated the molecular mechanisms by which BBR suppresses the growth of HER2-overexpressing breast cancer cells. The results show that BBR induces G1-phase cell cycle arrest by interfering with the expression of cyclins D1 and E and that it induces cellular apoptosis through the induction of a mitochondria/caspase pathway. The data also indicate that BBR inhibits cellular growth and promotes apoptosis by down-regulating the HER2/PI3K/Akt signaling pathway. Furthermore, it is also shown that a combination of taxol and BBR significantly slows the growth rate of HER2-overexpressing breast cancer cells. In conclusion, this study suggests that BBR could be a useful adjuvant therapeutic agent in the treatment of HER2-overexpressing breast cancer.  相似文献   

Extract of lotus leaf ( Nelumbo nucifera ) and its active constituent catechin with insulin secretagogue activity     

Huang CF  Chen YW  Yang CY  Lin HY  Way TD  Chiang W  Liu SH 《Journal of agricultural and food chemistry》2011,59(4):1087-1094

The effect of lotus leaf ( Nelumbo nucifera Gaertn.) on diabetes is unclear. We hypothesized that lotus leaf can regulate insulin secretion and blood glucose levels. The in vitro and in vivo effects of lotus leaf methanolic extract (NNE) on insulin secretion and hyperglycemia were investigated. NNE increased insulin secretion from β cells (HIT-T15) and human islets. NNE enhanced the intracellular calcium levels in β cells. NNE could also enhance phosphorylation of extracellular signal-regulated protein kinases (ERK)1/2 and protein kinase C (PKC), which could be reversed by a PKC inhibitor. The in vivo studies showed that NNE possesses the ability to regulate blood glucose levels in fasted normal mice and high-fat-diet-induced diabetic mice. Furthermore, the in vitro and in vivo effects of the active constituents of NNE, quercetin, and catechin, on glucose-induced insulin secretion and blood glucose regulation were evaluated. Quercetin did not affect insulin secretion, but catechin significantly and dose-dependently enhanced insulin secretion. Orally administered catechin significantly reversed the glucose intolerance in high-fat-diet-induced diabetic mice. These findings suggest that NNE and its active constituent catechin are useful in the control of hyperglycemia in non-insulin-dependent diabetes mellitus through their action as insulin secretagogues.  相似文献   

Parasitic plants and forests: a climate change perspective     

Way DA 《Tree physiology》2011,31(1):1-2

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Free enterprise in data compilation. Committees are urged to open a freeway for compilers rather than to guide and channel their steps     

K Way 《Science (New York, N.Y.)》1968,159(812):280-282

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Neuroanatomical correlates of morphine dependence   总被引：2，自引：0，他引：2  

E Wei  H H Loh  E L Way 《Science (New York, N.Y.)》1972,177(49):616-617

Naloxone hydrochloride, an opioid antagonist, was applied to several discrete brain regions of morphine-dependent rats to precipitate abstinence. Severe withdrawal signs were elicited after administration in the thalamus but not in neocortical, hippocampal, hypothalamic, or tegmental areas of the brain.  相似文献   

BEAN APHID CONTROL ON FIELD BEANS IN RELATION TO THE FLOWERING PERIOD AND TO HONEY BEE POISONING     

M. J. Way 《Plant pathology》1961,10(1):14-20

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Once I found out: Awareness of and attitudes toward coyote hunting policies in Massachusetts     

Jennifer L. Jackman  Jonathan G. Way 《Human Dimensions of Wildlife》2018,23(2):187-195

Lethal management of large carnivores such as wolves, cougars, bear, bobcat, and coyotes has been found to have negative ecological, behavioral, and socio-political consequences, and has contributed to human–wildlife conflict. Recent research has documented an increase in the popularity of large predators and decrease in support for their lethal removal, particularly when methods are perceived as inhumane or unfair. Our survey results indicated that voters on Cape Cod, Massachusetts overwhelmingly opposed coyote hunting practices such as baiting and supported changing these policies. We suggest that either (1) state wildlife agencies broaden their constituents to include the general public (i.e. not just hunters) in their decision-making; (2) citizens initiate more ballot initiatives to better protect carnivores; and/or (3) policymakers reform carnivore management in line with the compassionate conservation paradigm, which would likely have broad public support given our findings.  相似文献   

Validation of a KHV antibody enzyme‐linked immunosorbent assay (ELISA)          下载免费PDF全文

S M Bergmann  Q Wang  W Zeng  Y Li  Y Wang  M Matras  M Reichert  D Fichtner  M Lenk  T Morin  N J Olesen  H F Skall  P‐Y Lee  S Zheng  S Monaghan  S Reiche  W Fuchs  M Kotler  K Way  G Bräuer  K Böttcher  A Kappe  J Kielpinska 《Journal of fish diseases》2017,40(11):1511-1527

Koi herpesvirus (KHV) causes KHV disease (KHVD). The virus is highly contagious in carp or koi and can induce a high mortality. Latency and, in some cases, a lack of signs presents a challenge for virus detection. Appropriate immunological detection methods for anti‐KHV antibodies have not yet been fully validated for KHV. Therefore, it was developed and validated an enzyme‐linked immunosorbent assay (ELISA) to detect KHV antibodies. The assay was optimized with respect to plates, buffers, antigens and assay conditions. It demonstrated high diagnostic and analytical sensitivity and specificity and was particularly useful at the pond or farm levels. Considering the scale of the carp and koi industry worldwide, this assay represents an important practical tool for the indirect detection of KHV, also in the absence of clinical signs.  相似文献