Escherichia coli sepsis and endotoxemia in conscious young pigs     

E. Schrauwen  E. Cox  A. Houvenaghel 《Veterinary research communications》1988,12(4-5):295-303

In conscious pigs the influence of intravenous infusion of live E. coli (7×10⁸/kg), of the equivalent amount of endotoxin (20 g/kg) or of a high dose of endotoxin (2.5 mg/kg) on the hemodynamic, clinical and pathological parameters and on survival rate was studied. E. coli and endotoxin infusion resulted in pulmonary hypertension, systemic arterial hypotension, a decrease in cardiac output and an increase in heart rate. Clinical signs were characterized by respiratory and nervous disturbances, whereas necropsy revealed hemorrhages and edema in several organs. Although these findings were similar in the three groups, a marked difference in lethality was observed. Infusion of E. coli or of the high dose of endotoxin resulted in a significant mortality, whereas all pigs survived the infusion of the low dose of endotoxin. This suggests that the lethal pathophysiological mechanisms may only become activated when a sufficient amount of endotoxin is released into the circulation.  相似文献   

Bovine and canine acute phase proteins   总被引：1，自引：0，他引：1  

P. D. Eckersall  J. G. Conner 《Veterinary research communications》1988,12(2-3):169-178

Acute phase proteins are serum proteins which increase in concentration during the acute phase response to inflammation or infection. The response occurs in all animals, but in different species the response of individual proteins can be significantly different. Of the numerous acute phase proteins which have been identified in humans, a number have been examined in cattle and dogs but usually on an individual basis with little reference to their part in the acute phase response. Biochemical, physiological and clinical investigations into haptoglobin, fibrinogen, ₁-proteinase inhibitor, ceruloplasmin, seromucoid and C-reactive protein of cattle and dogs have therefore been reviewed with the emphasis on their role in this response to tissue damage.  相似文献   

Intrapopulation differences: population ecology of individuals     

Mertz DB 《Science (New York, N.Y.)》1988,241(4864):478

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Dolphin research     

Smuts B 《Science (New York, N.Y.)》1988,241(4864):400

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AMS Celebrates--and Worries     

Cipra BA 《Science (New York, N.Y.)》1988,242(4875):34

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Superstrings. A Theory of Everything? P. C. W. Davies and Julian Brown, Eds. Cambridge University Press, New York, 1988. viii, 234 pp., illus. $39.50; paper, $10.95. Based on a BBC radio broadcast     

Ovrut B 《Science (New York, N.Y.)》1988,242(4885):1584-1585

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Koop Floats a Plan; CDC Not Impressed     

B W 《Science (New York, N.Y.)》1988,239(4840):558

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Calculus: Crisis Looms in Mathematics' Future: Researchers and educators are debating how calculus should best be taught to increasingly recalcitrant students     

Cipra BA 《Science (New York, N.Y.)》1988,239(4847):1491-1492

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Doubts over fermat proof     

Cipra BA 《Science (New York, N.Y.)》1988,239(4847):1481

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Western Canada: rabies diagnoses january 1-june 30, 1987          下载免费PDF全文

Loewen K  Prins B 《The Canadian veterinary journal. La revue veterinaire canadienne》1988,29(2):173

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