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91.
Diagnosis of right coronary artery to right atrial fistula in a dog using two-dimensional echocardiography 总被引:1,自引:0,他引:1
G. J. Jacobs C. A. Calvert D. G. Hall M. Kraus 《The Journal of small animal practice》1996,37(8):387-390
A five-year-old boxer dog developed cardiac murmurs, complete heart block and car-diomegaly associated with vegetative bacterial endocarditis. Using two-dimensional echocardiography, vegetative lesions of the aortic valves and extension of the vegetations into the proximal right coronary artery and adjacent atrial septum were identified. The vegetation within the atrial septum appeared as a cavitated mass which protruded into the right atrium. Fistulae within the atrial septal vegetation permitting communication between the coronary artery and right atrium were observed with colour Doppler echocardiography. The dog died despite medical treatment. Post mortem examination confirmed the echo-cardiographic findings. Vegetative endocarditis with invasion into the right coronary artery and atrial septum producing fistulae and communication with the right atrium has not been reported previously in dogs. Doppler echocardiography proved useful in demonstrating the abnormal anatomy, intraluminal fistular blood flow and its communication with the right atrium. 相似文献
92.
Kelly Hall DVM Brian J. McCluskey DVM MS Wayne Cunningham DVM MS 《Journal of Equine Veterinary Science》2001,21(6):284
Following reports of an increase in the number of Corynebacterium pseudotuberculosis infections in horses in the western counties of Colorado in 1997, an epidemiological assessment of the problem was conducted using a survey of premises with affected horses. No gender, age or breed predilections were found. Most diagnoses of disease were made in the summer or fall of 1997. Abscesses were reported to occur in various locations with a mean healing time of 77 days. A majority of premises owners reported potential contact of horses with sheep or goats. The days of lost use and treatment costs per case had a mean of 13 days and $139, respectively. 相似文献
93.
W F Hall D P Bane C R Kilroy D L Essex-Sorlie 《Canadian journal of veterinary research》1990,54(2):238-243
A model for the induction of pneumonia caused by Pasteurella multocida type-A was developed. Anesthetized pigs were dosed intratracheally with 10(10) colony forming units of P. multocida type-A suspended in a total dose of saline based on the pig's body weight (8 mL/kg). A severe bronchopneumonia was present when the treated pigs were euthanized seven days postinfection. The mean percentage of pneumonic lesions in the treated pigs, as determined by morphometric measurement, was 14.03 +/- 7.01 (X +/- SD). In contrast, in the control pigs, the mean percentage of pneumonic lesions was 0.59 +/- 0.52. For the treated pigs during the period following induction of pneumonia, weight gain and feed intake were reduced significantly (p less than 0.05) compared to the controls. It was shown that severe pneumonia could be induced without the use of other infectious agents, which could potentially confound the experimental model. 相似文献
94.
M.C. French C.R. Hall J.M. Harrison T.D. Inch D.J. Sellers A.P. Smith D.G. Upshall P. Watts 《Pesticide biochemistry and physiology》1985,24(1):53-60
R(+)-Ethyl S-propyl methylphosphonothioate is bioactivated both in vivo and when perfused through isolated liver to give a product which is much more active as an inhibitor of acetylcholinesterase than the parent compound. The bioactivation does not occur in hepatectomised animals. Acetylcholinesterase inhibited by the active metabolite is not reactivated by pyridine-2-aldoxime methanesulphonate (P2S), whereas enzyme inhibited by the parent compound and its S(?) enantiomer is reactivatable. Attempts to identify the active metabolite were unsuccessful and experiments to explore its stability were inconclusive. Extensive in vitro studies of the inhibition of acetylcholinesterase by the enantiomers of ethyl S-propyl methylphosphonothioate and ethyl S-diisopropylaminoethyl methylphosphonothioates and subsequent reactivation of the enzyme by P2S showed that (a) there are large differences between the rates of inhibition of the R and S enantiomers of both compounds, (b) reactivation profiles are critically dependent on reaction conditions, and (c) the reactivation profiles of the R and S enantiomers of the former compound are indistinguishable under all conditions whereas differences are observed under some conditions for the latter pair of enantiomers. The results are discussed in terms of the possibility that the S-oxide of R(+)-ethyl S-propyl methylphosphonothioate is the active metabolite and it is concluded that this is unlikely. 相似文献
95.
Seven simple sugars, commonly used in intestinal function tests, were simultaneously administered intravenously to dogs and their urinary excretion was measured to assess their potential for metabolic degradation. Lactose, lactulose and 3-O-methyl-D-glucose were excreted unchanged, but small proportions of palatinose and sucrose were not, and were assumed to have been metabolised. More than half of the administered D-xylose and a quarter of L-rhamnose was not excreted and was assumed to have been metabolised. These findings may be significant for the interpretation of differential sugar absorption tests and the D-xylose tolerance test. 相似文献
96.
Characteristics of canine melanomas and comparison of histology and DNA ploidy to their biologic behavior 总被引:3,自引:0,他引:3
The biologic behavior of 179 formalin-fixed, paraffin-embedded canine melanomas was correlated with their histologic appearance. In addition, flow cytometric analysis of DNA content was performed on 54 of these tumors. Histologic examination accurately predicted clinical course in 89% of the melanomas with known behavior. Flow cytometry accurately predicted behavior in 93% of tumors with diagnostic histograms and demonstrated malignant features in 100% of metastases from malignant oral tumors; histograms were non-diagnostic for 15% of tumors tested. Histologic examination, flow cytometry, and biologic behavior were in agreement for 93% of the tumors with diagnostic histograms. Interpretive problems were encountered in analyzing heavily pigmented melanomas using this flow cytometry technique. 相似文献
97.
98.
99.
100.
T. J. Hall 《Euphytica》1980,29(1):189-197
Summary There are three known tomato mosaic virus (TMV) resistance factors, Tm-1, Tm-2 and Tm-2
2, in the tomato. Tm-2
2 is currently the most widely utilised in glasshouse cultivars. Both Tm-2 and Tm-22 can induce systemic necroses in response to virus infection. These are considered to be hypersensitive resistance reactions in view of the low virus concentrations in affected plants and because sub-inoculation usually fails to infect all plants possessing the same resistance gene. The literature relating to TMV resistance at the Tm-2 locus in the tomato is reviewed.Virulent strains may readily establish when Tm-1 or Tm-2 are used, but Tm-2
2 confers more effective resistance. The possible development of aggressive isolates capable of affecting Tm-2
2/Tm-22 plants is discussed. The establishment of virus types which cause systemic necrosis at normal growing temperatures is considered more likely than widespread infection from fully virulent strain 22 mutants. However, the growing of crops isolated from the TMV reservoirs in the soil considerably reduces the likelihood of even this occurring. 相似文献