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154.
Plasma biomarkers profile of female dogs with mammary carcinoma and its association with clinical and pathological features
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R. P. Soares L. G. R. Ribeiro K. A. Damasceno A. T. Costa A. Teixeira‐Carvalho O. A. Martins‐Filho G. D. Cassali 《Veterinary and comparative oncology》2016,14(1):88-100
The immunological biomarkers profiles were evaluated using Luminex as putative measures to monitor canine mammary carcinomas (MCs). Forty female dogs were categorized into benign mixed tumour (MC‐BMT = 28) and mammary carcinoma (MC=12). The ascendant biomarker signatures were used to compare the groups. For example, a higher frequency of MC‐BMT animals producing IL‐6, CXCL‐8 and CXCL‐10 was observed, whereas for the MC group IL‐2 and CXCL‐8 were detected. MC‐BMT animals without metastasis had an increase in the levels of IL‐2, CXCL‐8, CXCL‐10, IL‐6, TNF‐α, IL‐15 and a decrease in IL‐10 and CXCL‐8. MC‐BMT animals with metastasis showed only an increase in CXCL‐10 and a decrease in IL‐18. After comparing the ascendant signatures following the presence of metastasis in both groups, a higher frequency of dogs exhibiting IL‐10 production was observed. Pearson correlation (P = 0.0273) and receiver operating characteristic (ROC) curve analysis revealed that this pattern was associated with worse outcome and lower survival rates in MC animals. 相似文献
155.
A comparison of clinical,magnetic resonance imaging and pathological findings in dogs with gliomatosis cerebri,focusing on cases with minimal magnetic resonance imaging changes‡
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R. T. Bentley G. N. Burcham H. G. Heng J. M. Levine R. Longshore S. Carrera‐Justiz K. Kopf M. A. Miller 《Veterinary and comparative oncology》2016,14(3):318-330
The primary study objective was to determine whether clinical examination and magnetic resonance imaging (MRI) can underestimate canine gliomatosis cerebri (GC); we also investigated immunohistochemical features. Seven dogs with GC were studied; four recruited specifically because of minimal MRI changes. Neuroanatomic localization and the distribution of MRI, gross and sub‐gross lesions were compared with the actual histological distribution of neoplastic cells. In six cases, clinical examination predicted focal disease and MRI demonstrated a single lesion or appeared normal. Neoplastic cells infiltrated many regions deemed normal by clinical examination and MRI, and were Olig2‐positive and glial fibrillary acid protein‐negative. Four dogs had concurrent gliomas. GC is a differential diagnosis for dogs with focal neurological deficits and a normal MRI or a focal MRI lesion. Canine GC is probably mainly oligodendrocytic. Type II GC, a solid glioma accompanying diffuse central nervous system neoplastic infiltration, occurs in dogs as in people. 相似文献
156.
Differentiation between dogs with thrombosis and normal dogs using the overall hemostasis potential assay
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![点击此处可从《Journal of Veterinary Emergency and Critical Care》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Anna L. Dengate BVSc BMedSc Marie‐Christine Morel‐Kopp PhD Julia A. Beatty PhD BVetMed BSc Vanessa Barrs BVSc MVetClinStud Jody A. Braddock BVSc MVetClinStud Richard K. Churcher BVSc Bethany J. Wilson BVSc PhD Christopher M. Ward BMedSc MBChB PhD 《Journal of Veterinary Emergency and Critical Care》2016,26(3):446-452
157.
Rita M. Hanel DVM DACVIM DACVECC Lee Palmer DVM MS DACVECC NREMT‐T WEMT CCRP Janice Baker DVM DACVPM Jo‐Anne Brenner BA EMT‐I EMT‐T David Dorman DVM PhD DABVT John C. Gicking DVM DACVECC Brian Gilger DVM MS DACVO DABT Cynthia M. Otto DVM PhD DACVECC DACVSMR Elizabeth Rozanski DVM DACVECC DACVIM Brian Trumpatori DVM 《Journal of Veterinary Emergency and Critical Care》2016,26(2):166-233
158.
The practice of catch-and-release fishing has been widely promoted by angling fraternities as a fisheries manage- ment tool. The aim of this investigation was to determine the physiological response of Orange-Vaal smallmouth yellowfish, Labeobarbus aeneus, to catch-and-release angling in the Vaal River, South Africa. Fish were collected using standard fly-fishing techniques, anaesthetised in clove oil and blood was drawn from the caudal vein; thereafter the fish were weighed, measured, revived and released. Blood plasma was analysed for concentra- tions of glucose, cortisol and lactate to determine the effects of angling duration, fish size and water tempera- ture. Larger fish were angled for a longer duration compared with smaller fish. Levels of glucose were affected by water temperature (influenced by time of year). Plasma glucose concentrations decreased with greater angling duration. Few individuals (n = 12) showed increased plasma cortisol concentrations. In extended-capture fish (angled for >1 min), lactate concentrations increased significantly above values for rapid-capture fish (angled for >30 s). These data suggest that catch-and-release causes physiological stress to fish, but nonetheless this practice can be a valuable fisheries management tool to ensure the sustainability of fish populations. Other factors beyond the ‘angling’ time are likely to contribute to physiological disruptions in homeostasis and therefore handling and air exposure of angled fish should be included in future catch-and–release angling studies. In addition, the longer-term impact of angling on fish health should also be determined. 相似文献
159.
In the Upper Zambezi and Okavango ecoregions, Brycinus lateralis, Hepsetus cuvieri, Schilbe intermedius and Serranochromis macrocephalus are important in subsistence fisheries, while S. intermedius and S. macrocephalus are often caught in commercial catches. Despite their importance, there is little information on their age and growth and age validation. Growth zone deposition rate in otoliths of B. lateralis, H. cuvieri, S. intermedius and S. macrocephalus was validated as annual using edge analysis in this study. Annual deposition of growth zones was corroborated by a fluorochrome marking experiment. Both methods demonstrated that one growth zone was deposited annually. Edge analysis demonstrated that the highest proportion of opaque zones was detected between August and December, most likely as a result of slow growth during lower temperature water during the preceding winter. With growth zone deposition validated as annual, future research should focus on determining the growth, maturity and mortality rates of these species, parameters which are important for their management. 相似文献