Pathology of ten cases of canine primary lung tumor     

A Nii  H Nakayama  R Takahashi  K Fujiwara 《Nippon juigaku zasshi. The Japanese journal of veterinary science》1985,47(5):811-815

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Effect of reticuloendothelial system blocking on Tyzzer's disease of mice     

H Nakayama  A Nii  S Oguihara  S Inoue  N Okada  K Fujiwara 《Nippon juigaku zasshi. The Japanese journal of veterinary science》1986,48(2):211-217

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Liver lesions in mice treated with diethylnitrosamine and inoculated with the Tyzzer's organism     

A Nii  H Nakayama  S Inoue  K Fujiwara 《Nippon juigaku zasshi. The Japanese journal of veterinary science》1987,49(1):185-189

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Two cases of canine insulinoma     

K Midoro  H Nakayama  N Okada  K Ono  K Yasuda  K Sawa  R Takahashi  K Fujiwara 《Nippon juigaku zasshi. The Japanese journal of veterinary science》1987,49(6):1151-1153

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Enteritis due to feline infectious peritonitis virus   总被引：1，自引：0，他引：1  

T Hayashi  Y Watabe  H Nakayama  K Fujiwara 《Nippon juigaku zasshi. The Japanese journal of veterinary science》1982,44(1):97-106

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Trickle irrigation: Emitter clogging and other flow problems     

R.G. Gilbert  F.S. Nakayama  D.A. Bucks  O.F. French  K.C. Adamson 《Agricultural Water Management》1981,3(3):159-178

Trickle irrigation experiments with Colorado River water on citrus trees in southwestern Arizona were conducted to develop water treatment methods for preventing emitter clogging and maintaining long-term operation of the system under actual field conditions. Eight trickle emitter systems in combination with six water treatments were evaluated during a comprehensive 4-year study. Emitter clogging was related to emitter design and to degree of filtration treatments of Colorado River water. If not positioned upright, emitters designed with moving parts were more susceptible to malfunctioning and clogging. Emitters with flexible membranes either failed after a few months of use with chemically conditioned water or showed serious deterioration and decomposition after 4 years. Five of the eight emitter systems required sand and screen (200 mesh) filtration plus chemically conditioned water to keep suspended materials from physically clogging the emitter. However, two emitter systems with the same design but different flow rates have continued to operate with only screen (50 mesh) filtration. For emitters unaffected by material deterioration, the water conditioned continuously with acid alone was just as effective as a combination of continuous or intermittent chlorine and acid treatments in reducing emitter clogging. The dominant causes of emitter clogging and flow reduction were physical particles; next, and minor in comparison, was the combined development of biological and chemical deposits.  相似文献   

Evaluation of the low dose level of a heat-killed and dried cell preparation of Enterococcus faecalis to prevent porcine edema disease using experimental infection model with enterotoxcemic Escherichia coli in weaning pigs   总被引：1，自引：0，他引：1  

Tsukahara T  Inoue R  Nakanishi N  Nakayama K  Matsubara N  Ushida K 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2007,69(2):103-109

Porcine edema disease (ED) is caused by Shiga toxin 2e-producing Escherichia coli (STEC). ED has become frequent in pig farms, and the use of antimicrobials has resulted in the development of antimicrobial-resistant STEC. Accordingly, the use of materials other than antimicrobials is requested for the prevention of ED. Oral administration of a heat-killed and dried cell preparation of Enterococcus faecalis strain EC-12 (EC-12) to weaning pigs was previously demonstrated to decrease animal mortality in a STEC-contaminated farm at 0.05% (w/w) dose level. In this study, pigs experimentally infected with STEC were used as a model for ED to evaluate the low dose level of EC-12 to prevent ED. Fifteen 21-day-old pigs were divided into 5 groups: STEC challenge with the basal diet, STEC challenge with EC-12 supplemented at 0.005, 0.01, or 0.05% (w/w) to the basal diet, and no STEC challenge with the basal diet. The challenge was carried out when the animals were 25, 26, and 27 days old using STEC contained in capsules resistant against gastric digestion. All pigs were euthanized at 32 days of age. The daily weight gain, feed conversion ratio, and palpebral edema were improved by supplementation with 0.05% EC-12, but not by the low dose levels. Accordingly, 0.05% level of supplementation was needed for EC-12 to improve clinical symptoms in weaning piglets infected by STEC.  相似文献   

Histopathological characteristics of Kupffer cells and ito cells in the porcine and bovine liver     

Uetsuka K  Nishikawa S  Isobe K  Nakayama H 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2007,69(7):767-770

We previously reported that no Kupffer cells reacted with the antibody against lysozyme, and Ito cells contained a large cytoplasmic vacuole in the feline liver. In this report, we further examined the characteristics of porcine and bovine hepatic non-parenchymal cells. In the liver of both animals, Kupffer cells were positive for lysozyme, and cytoplasmic vacuoles in Ito cells were small. The histopathological characteristics of porcine and bovine hepatic non-parenchymal cells were different from those of the feline liver.  相似文献   

Intramuscular fat deposition in principal muscles from twenty-four to thirty months of age using identical twins of Japanese Black steers     

Okumura T  Saito K  Sakuma H  Nade T  Nakayama S  Fujita K  Kawamura T 《Journal of animal science》2007,85(8):1902-1907

The changes in i.m. fat deposition in the principal muscles [M. semitendinosus, M. semimembranosus, M. psoas major, M. latissimus dorsi, LM (7th to 8th and 10th to 11th thoracic vertebrae), and M. supraspinatus] from 24 to 30 mo of age were investigated using identical twins of Japanese Black steers. Four sets of identical twins of Japanese Black steers were used in this study. Animals were fattened from 10 to 24 or 30 mo of age for each pair of identical twins. Body weights of twin steers slaughtered at 24 and at 30 mo of age were similar at 10 mo of age and thereafter up to 24 mo of age. The changes in serum concentration of vitamin A, glucose, total cholesterol, albumin, and total protein were similar in each pair of twins during the first fattening stage (10 to 24 mo). Fat contents of LM (7th to 8th thoracic vertebrae) at 24 and 30 mo of age were 37.0 and 42.4%, respectively (P < 0.05). Moreover, in the principal muscles, except M. semimembranosus and M. supraspinatus, fat content at 30 mo of age was greater than at 24 mo of age (P < 0.05). The proportional increase in fat content from 24 to 30 mo of age was greatest in M. semitendinosus (+58.7%) and least in M. supraspinatus (+6.1%). These results demonstrate that i.m. fat continues to increase after 24 mo of age, and the rates of i.m. fat deposition and the ages when i.m. fat is deposited are different for every muscle.  相似文献   

Dietary curcumin supplementation attenuates 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxicity in C57BL mice     

Xi-Jun He  Kazuyuki Uchida  Chiaki Megumi  Nobuaki Tsuge  Hiroyuki Nakayama 《Journal of toxicologic pathology》2015,28(4):197-206

Studies in vivo and in vitro suggest that curcumin is a neuroprotective agent. Experiments were conducted to determine whether dietary supplementation with curcumin has neuroprotective effects in a mouse model of Parkinson’s disease (PD). Treatment with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) significantly induced the loss of dopaminergic cells in the substantia nigra and deletion of dopamine in the striatum, which was attenuated by long-term (7 weeks) dietary supplementation with curcumin at a concentration of 0.5% or 2.0% (w/w). Although curcumin did not prevent the MPTP-induced apoptosis of neuroblasts in the subventricular zone (SVZ), it promoted the regeneration of neuroblasts in the anterior part of the SVZ (SVZa) at 3 days after MPTP treatment. Furthermore, curcumin enhanced the MPTP-induced activation of microglia and astrocytes in the striatum and increased the expression of glial cell line-derived neurotrophic factor (GDNF) and transforming growth factor-β1 (TGFβ1) in the striatum and SVZ. GDNF and TGFβ1 are thought to play an important role in protecting neurons from injury in the central and peripheral nervous systems. These results suggest that long-term administration of curcumin blocks the neurotoxicity of MPTP in the nigrostriatal dopaminergic system of the mouse and that the neuroprotective effect might be correlated with the increased expression of GDNF and TGFβ1. Curcumin may be effective in preventing or slowing the progression of PD.  相似文献