Surfactant protein D expression in normal and pneumonic ovine lung     

Grubor B  Gallup JM  Ramírez-Romero R  Bailey TB  Crouch EC  Brogden KA  Ackermann MR 《Veterinary immunology and immunopathology》2004,101(3-4):235-242

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Copper metabolism and oxidative stress in chronic inflammatory and cholestatic liver diseases in dogs     

Spee B  Arends B  van den Ingh TS  Penning LC  Rothuizen J 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2006,20(5):1085-1092

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Highly conserved protective epitopes on influenza B viruses   总被引：1，自引：0，他引：1  

C Dreyfus  NS Laursen  T Kwaks  D Zuijdgeest  R Khayat  DC Ekiert  JH Lee  Z Metlagel  MV Bujny  M Jongeneelen  R van der Vlugt  M Lamrani  HJ Korse  E Geelen  Ö Sahin  M Sieuwerts  JP Brakenhoff  R Vogels  OT Li  LL Poon  M Peiris  W Koudstaal  AB Ward  IA Wilson  J Goudsmit  RH Friesen 《Science (New York, N.Y.)》2012,337(6100):1343-1348

Identification of broadly neutralizing antibodies against influenza A viruses has raised hopes for the development of monoclonal antibody-based immunotherapy and "universal" vaccines for influenza. However, a substantial part of the annual flu burden is caused by two cocirculating, antigenically distinct lineages of influenza B viruses. Here, we report human monoclonal antibodies, CR8033, CR8071, and CR9114, that protect mice against lethal challenge from both lineages. Antibodies CR8033 and CR8071 recognize distinct conserved epitopes in the head region of the influenza B hemagglutinin (HA), whereas CR9114 binds a conserved epitope in the HA stem and protects against lethal challenge with influenza A and B viruses. These antibodies may inform on development of monoclonal antibody-based treatments and a universal flu vaccine for all influenza A and B viruses.  相似文献   

Reversible pulmonary hypertension associated with lungworm infection in a young cat     

Mark Dirven  Viktor Szatmári  Ted van den Ingh  Rolf Nijsse 《Journal of Veterinary Cardiology》2012,14(3):465-474

Two ten-week-old kittens presented with dyspnea. Two weeks later dyspnea had worsened and both kittens had developed a heart murmur. One kitten died and necropsy showed severe granulomatous pneumonia and moderate bronchi(oli)tis and peribronchi(oli)tis caused by Aelurostrongylus abstrusus. The results from echocardiography, thoracic radiography and the other kitten's fecal examination were interpreted as severe parasitic pneumonia caused by A. abstrusus infection with pulmonary hypertension. Repeated administration of milbemycine-oxime and praziquantel resulted in cessation of larvae shedding and resolution of clinical, radiographic and echocardiographic signs of bronchopneumonia and pulmonary hypertension.  相似文献   

Nutritive Value of Four Soybean Products in Diets for Atlantic Salmon (Salmo salar,L.)     

Jan J. Olli  Åshild Krogdahl  Ted S. G. A. M. van den Ingh  Lars E. Brattås 《Acta Agriculturae Scandinavica, Section A - Animal Sciences》2013,63(1):50-60

Abstract

Four processed soybean products were evaluated as protein sources for Atlantic salmon: solvent-extracted soybean meal (SBM44), dehulled and solvent-extracted soybean meal (SBM50), dehulled full-fat soybean meal (FFSBM) and soybean concentrate (SBC). The soybean products replaced high-quality fish meal at levels corresponding to 0, 14, 28, 42 and 56% soybean protein of total protein.

Dietary inclusion of SBC, at the expense of fish meal, did not affect weight gain, carcass lipids, fecal excretion of nutrients or fecal dry matter content significantly. The nutritive value of the SBC protein appeared comparable to that of the fish meal. The three other soybean products impaired performance increasingly with increasing levels of inclusion, indicating lower nutritive value than for the fish meal. The favourable results seen with SBC indicated a great potential of soybean to become an important protein source for Atlantic salmon through improved processing.  相似文献   

In vitro and in vivo bioactivity of recombinant canine hepatocyte growth factor   总被引：1，自引：0，他引：1  

Arends B  Spee B  Hoffmann G  Jansen GE  Slump E  Auriemma E  Ijzer J  Hemrika W  Romijn RA  van der Heijden-Liefkens KH  Sondermeijer PJ  van den Ingh TS  Penning LC  Rothuizen J 《Veterinary journal (London, England : 1997)》2008,178(1):70-77

Hepatocyte growth factor (HGF) is crucial for the development and regeneration of the liver and offers a possible new therapeutic strategy for the treatment of canine liver disease. In this study, the in vitro and in vivo bioactivity of recombinant canine HGF (rcHGF) produced with a baculoviral expression system in insect cells was measured. In vitro rcHGF induced mitogenesis, motogenesis, and phosphorylated the HGF receptor c-MET and its downstream mediators PKB and ERK1/2 in two canine epithelial cell lines. After a partial hepatectomy (phx) in dogs, rcHGF increased phosphorylation of c-MET, PKB and ERK1/2. A moderate increase was seen with the cell cycle protein PCNA in rcHGF treated livers, but no HGF-induced increase in liver weight was seen 7 days after phx. Furthermore, rcHGF treated livers showed lower levels of the key mediator of apoptosis, caspase-3, at 7days after phx. It is concluded that rcHGF is a biologically active protein in vitro and in vivo and the baculoviral expression system supplies sufficient amounts of rcHGF for future clinical studies in dogs.  相似文献   

Physiologically based modelling of the pharmacokinetics of three beta‐lactam antibiotics after intra‐mammary administration in dairy cows     

Andrew P. Woodward  Ted Whittem 《Journal of veterinary pharmacology and therapeutics》2019,42(6):693-706

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Hans Løkke and Cornelis A.M. van Gestel: Handbook of Soil Invertebrate Toxicity Tests     

Wu  Ted  Awate  Hiroshi 《Water, air, and soil pollution》1999,116(3-4):669-670

Water, Air, &; Soil Pollution -  相似文献   

Data envelopment analysis for production efficiency improvement: An empirical application on brine shrimp Artemia franciscana culture in the Mekong Delta,Vietnam     

Nguyen Phuoc Vinh  Cheng Ting Huang  Yao Jen Hsiao  Truong Khac Hieu  Li Hsueh Chen 《Aquaculture Research》2020,51(7):2985-2996

Artemia culture in the Mekong Delta, Vietnam, is becoming more and more important to satisfy the global demands of cyst production. Nevertheless, Artemia cyst productivity in the Mekong Delta has been fluctuating largely due to not only technical inefficiencies and external factors but also farms’ characteristics. This study employed a data envelopment analysis to evaluate the production efficiencies in correlation with biological and cost inputs of Artemia culture in Vinh Chau and Bac Lieu located in the Mekong Delta. The key factors affecting technical efficiency (TE) were determined using ordinary least squares regression model. The empirical results indicated that production efficiencies of farms in Vinh Chau and Bac Lieu were similar with metatechnology ratios of 0.97 and 0.96 respectively. About 62.8% of surveyed farms were operating in technically inefficient circumstances. Farmers’ experience, educational level and culture technique training participation had positive effects on TE, while climate effects and water problems have been proved to have negative effects on TE. To improve production efficiency, inefficient farms are suggested to have moderately increasing combinations of organic fertilizer, chemical and feed. The use of probiotics should be reduced as it increases production cost and affects TE. Notably, a collaboration of scientists and feed processing companies is recommended to produce a specific formulated feed for Artemia in commercial scales. This study also proposes adaptive policies for local governments and cooperatives to assist coastal famers in the Mekong Delta overcome technical inefficiencies, improve cyst productivity and obtain economic sustainability in Artemia culture.  相似文献   

Priming of cowpea volatile emissions with defense inducers enhances the plant's attractiveness to parasitoids when attacked by caterpillars          下载免费PDF全文

Toby JA Bruce  Ted CJ Turlings 《Pest management science》2018,74(4):966-977

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