Pathologic consequences of a severe influenza outbreak (swine virus A/H1N1) under natural conditions in the non-immune sow at the beginning of pregnancy     

F Madec  C Kaiser  J M Gourreau  F Martinat-Botte 《Comparative immunology, microbiology and infectious diseases》1989,12(1-2):17-27

Pathological consequences of a severe outbreak of swine influenza (H1N1 virus) in the non immune sow at the beginning of pregnancy, under natural conditions. A sudden acute outbreak of fever, depression, anorexia and coughing in a group of nulliparous sows from a herd that was currently under epidemiological investigation lead to build a particular disposal of observation. The clinical signs were daily recorded including rectal temperature. Blood was taken from the sows at the beginning of the troubles and 3 weeks later for the detection of Aujesky's disease, coronavirus TGE-like, Influenza viruses A/H1N1 and A/H3N2 and Mycoplasma hyopneumoniae. Viral detection was attempted from nasal swabs and aborted fetuses during the acute phase. The clinical study showed fever reaching near 41 degrees C on most of the pigs and lasting usually from 2 to 5 days. The diagnosis of Influenza (virus swine H1N1) was established both on serology (massive seroconversion) and on the detection of the virus from the nasal swabs and from an aborted fetus. The control of the lungs of sows "not in pig" and culled showed extended lesions of bronchopneumonia and Pasteurella multocida was found. The technical consequences of this severe outbreak of Influenza on reproduction were mainly important at the beginning of pregnancy. Over 13 sows inseminated less than 1 week before the outbreak, only 3 farrowed (respectively 5.5 and 12 piglets); 7 returned to oestrus and 3 "not a pig" at 21 days (echotomography) did not show signs of heat and were culled. Over 8 pregnant sows (1 month of pregnancy), 6 farrowed normal litters and total embryonic resorption occurred in 2 sows. Over 18 pregnant sows (more than 45 days gestation) one aborted.  相似文献   

The intravenous bile Acid loading test in the goat: determination of a procedural protocol and reference values     

Hagemoser WA 《Veterinary clinical pathology / American Society for Veterinary Clinical Pathology》1989,18(1):17-20

An intravenous bile acid loading test was performed on 16 goats using various dosages and sampling protocols. A recently developed enzymatic bile acid assay provided an economical and technologically simple method for bile acid analysis. Intravenous injection of bile salts into goats was well tolerated. Clearance times were rapid. A protocol for performance of the test was suggested and a practical reference range for T 1/2 clearance of 4+/-1 minute was determined. Further investigations of this test in the assessment of liver function in the ruminant appear warranted.  相似文献   

What Is Your Diagnosis?     

Lowseth LA  Herbert RA  Muggenburg BA  Gillett NA  Rebar AH 《Veterinary clinical pathology / American Society for Veterinary Clinical Pathology》1989,18(3):57-57

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Effects of phenylbutazone and indomethacin on the post-operative course following experimental orthopaedic surgery in dogs     

Susan W. Mbugua  Lasse A. Skoglund  Per Lkken 《Acta veterinaria Scandinavica》1989,30(1):27-35

Randomized placebo-controlled crossover studies were carried out in dogs to evaluate how two non-steroidal anti-inflammatory drugs (NSAID) might modulate an acute post-traumatic inflammatory reaction. Two "identical" surgical interventions were performed on the forelimbs of each animal with an interval of 28 days, to enable a paired comparison of the inflammatory signs and the wound/bone healing processes. At one operation 8 dogs received 300 mg phenylbutazone twice daily for 8 days starting on the day before surgery, and at the other operation matching placebo tablets were given. In a similar placebo-controlled trial another group of 8 dogs received 5 mg indomethacin twice daily. With phenylbutazone the post-operative swelling was not significantly reduced compared to placebo, but there was less pain and limping. With indomethacin the swelling was somewhat reduced, but there was no consistent difference to placebo in the pain and limping assessments. None of the drugs appeared to distinctly effect the wound or fracture healing, as evaluated by clinical inspection, comparison of radiographs and comparison of bone sections from the sites of surgery. It proved difficult to select an appropriate dosage of indomethacin due to its high potential to induce GI ulceration and bleeding in dogs. In this experimental surgical model with an acute inflammation, neither phenylbutazone nor indomethacin showed impressive anti-inflammatory or analgesic properties. In the same model paracetamol has proved to significantly and more efficiently, reduce both swelling and pain without any noticeable adverse effects, and appears to be a better alternative than the two presently tested NSAID.  相似文献   

Winter scours in sheep - an obsolete term     

Orr MB  Jopp A 《New Zealand veterinary journal》1989,37(1):38-39

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Neurotoxic syndrome of sheep due to the ingestion of plants of the Mediterranean scrub: clinical, histopathological, histochemical and ultrastructural observations     

A Leoni  A M Nieddu  F Guarda  M Castagnaro  A Firinu  P Cossu  V Mingioni 《Schweizer Archiv für Tierheilkunde》1989,131(6):361-368

A severe neurological disorder was observed during a very dry season, in sheep pasturing on land with mediterranean vegetation. During the crisis, lasting 5-20", ataxia and convulsions were the main clinical signs. Brain congestion, spongy appearance of the liver, interstitial nephritis and hyperpigmentation of visceral lymph nodes were the most important macroscopic lesions. Histopathological, histochemical and ultrastructural findings confirmed liver and kidney lesions and showed considerable neurovisceral storage of lipofuscin. Although further toxicological and experimental studies are needed to elucidate the origin of the disease, the Authors attribute the outbreak of the neurological syndrome to the ingestion of a neurotoxin containing plant.  相似文献   

A gastric motility disorder in a dog          下载免费PDF全文

Flock MA 《The Canadian veterinary journal. La revue veterinaire canadienne》1989,30(11):904

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The influence of a premating injection of gonadotrophin-releasing hormone on sow and gilt fertility          下载免费PDF全文

Kirkwood RN  Thacker PA 《The Canadian veterinary journal. La revue veterinaire canadienne》1989,30(12):959-960

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Association of weak estrual signs and irregular estrous cycles with hypothyroidism in a bitch          下载免费PDF全文

Peter AT  Gaines JD  Smith CL 《The Canadian veterinary journal. La revue veterinaire canadienne》1989,30(12):957-958

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Outbreaks of budgerigar fledgling disease in three aviaries in Ontario          下载免费PDF全文

Gough JF 《The Canadian veterinary journal. La revue veterinaire canadienne》1989,30(8):672-674

Outbreaks of budgerigar fledgling disease (BFD) occurred in three budgerigar aviaries in Ontario. Acute death in seven to ten-day-old nestlings and feather abnormalities in birds over three weeks of age were common findings. Ascites, hepatomegaly and hydropericardium were prominent gross lesions. Histologically, basophilic intranuclear inclusions were seen in many tissues. A severe drop in hatchability occurred in one aviary—a finding not previously reported with BFD. Interruption of breeding controlled the disease in aviary 1, but failed in two consecutive attempts in aviary 2. A third outbreak occurred in aviary 2 after depopulation and restocking. In aviary 3, the spread of disease was very rapid; 90% of the nestlings died within a few weeks. A papovavirus similar to a previously described isolate was recovered in this outbreak.  相似文献