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21.
Pintar T Pleskovic A Alessiani M Abbiati F Milutinović A Petrovic D Pogacnik M Zorc-Pleskovic R 《Acta veterinaria Hungarica》2007,55(4):533-541
Intestinal transplantation is being increasingly performed to treat patients with irreversible intestinal failure. The major cause of intestinal graft failure is graft-versus-host disease (GVHD) that represents a life-threatening complication after small bowel transplantation (Itx). The purpose of this study was to assess the diagnostic and prognostic value of skin biopsy histological changes for acute GVHD after Itx in pigs. Thirty-four Large White pigs were divided into three groups: Group 1 with Itx only, Group 2 with Itx and donor bone marrow infusion (Itx BM) and Group 3 (control group - before the operation). Animals received tacrolimus-based immunosuppression from day 0 to day 30 postoperatively. Skin and small bowel biopsies were histologically assessed, analysed and classified from grade 1 to 4 on postoperative days 15, 30, 45 and 60. There was a strong correlation between the histological grading values of skin biopsy changes and the histological grading values of small bowel biopsy changes (Kendall's tau_b is 0.855 for the Itx group and 0.730 for the Itx BM group). The significant correlation found between skin and small bowel histological changes suggests the prognostic value of skin biopsies after Itx. In conclusion, our findings emphasise the diagnostic and prognostic value of skin biopsy analysis for acute GVHD after Itx. 相似文献
22.
Antibacterial activity of Cichorium intybus 总被引：1，自引：0，他引：1
Antibacterial activity of the water, ethanol and ethyl acetate extracts of Cichorium intybus was investigated. All the tested extracts showed antibacterial activity, the ethyl acetate extract being the most active. Water extract inhibits Agrobacterium radiobacter sp. tumefaciens, Erwinia carotovora, Pseudomonas fluorescens and P. aeruginosa. 相似文献
23.
D. Lupulovic J. Maksimovic Zoric N. Vaskovic D. Bugarski B. Plavsic N. Ivanovic T. Petrovic I. Pusic D. Marcic Z. Grgic S. Lazic 《Zoonoses and public health》2015,62(8):625-636
Rabies is one of the oldest known zoonotic diseases that has significant impact on public health, but still remains neglected in Serbia. Rabies virus can infect humans and other mammals and causes inflammation of the brain associated with encephalomyelitis and neurological symptoms. In 2010, Veterinary Directorate (national Competent Authority for animal health in Serbia) has started multi‐annual project of oral rabies vaccination of foxes and other wild carnivores (e.g. jackals), as support of long‐term programme of eradication of rabies in Serbia, co‐funded by EU (financed by Instrument for Pre‐Accession Assistance). Monitoring of the effectiveness of oral vaccination campaigns has been carried out in continuation from 2011 and was based on: (i) post‐mortem laboratory examination of brain tissue of target animals (foxes, jackals and other carnivores) by fluorescent antibody test (FAT), (ii) detection of antibodies against rabies virus in serum samples by ELISA and (iii) detection of tetracycline biomarker in the mandibles for the evaluation of vaccine bait uptake. From September 2011 to May 2014, the total number of 4943 brain tissue samples, 4241 sera and 4971 mandibles were analysed. Confirmed rabies‐positive brains decreased from 10 in 2011/2012 to 6 in 2012/2013 and eventually to 1 positive case in 2013/2014. The seroconversion rate increased from 10.48% (133/1269) in 2011/2012 to 20.11% (362/1800) in 2012/2013 and 42.23% (495/1172) in 2013/2014. Along with the seroconversion, the number of detected tetracycline‐positive mandibles demonstrated an increasing tendency in the same period, being 49.67% (682/1373) in 2011/2012, 62.60% (1294/2067) in 2012/2013 and 90.33% (1383/1531) in the monitoring programme carried out in 2013/2014. Presented results confirmed that ORV of foxes and other wildlife in Serbia against rabies was successful and characterized by steady increase of vaccine baits uptake and immunization of animals. 相似文献
24.
C-banding, which stains the heterochromatic regions of chromosomes, was utilized in order to ascertain whether or not several varieties from a Yugoslavian wheat-breeding program contained a 1RS/1BL substitution or a 1RS/1BL translocation. Only one variety contained the 1R (1B) substitution, while in the remaining sixteen varieties, the 1RS/1BL translocation was present. The C-banding results were confirmed utilizing an SDS-PAGE analysis, and the results indicated that both techniques should be used together. In all of the Yugoslavian wheats containing observable rye chromatin, the C-band corresponding to the nucleolus organizing region (NOR) was clearly reduced over that found in the wheat parents used in Yugoslavia or the other wheats from around the world containing either the substitution or the trans location. Some unknown selection pressure applied in the Yugoslavian wheat program in Novi Sad over the years has evidently caused a deletion of most of the rye NOR region. 相似文献
25.
It has been suggested that placebo analgesia involves both higher order cognitive networks and endogenous opioid systems. The rostral anterior cingulate cortex (rACC) and the brainstem are implicated in opioid analgesia, suggesting a similar role for these structures in placebo analgesia. Using positron emission tomography, we confirmed that both opioid and placebo analgesia are associated with increased activity in the rACC. We also observed a covariation between the activity in the rACC and the brainstem during both opioid and placebo analgesia, but not during the pain-only condition. These findings indicate a related neural mechanism in placebo and opioid analgesia. 相似文献
26.
M. Zivojinovic G. Dimitrijevic M. Lazic M. Petrovic Lj. Sofronic-Milosavljevic 《Veterinary parasitology》2009,159(3-4):358-360
Endemic trichinellosis is re-emerging in Serbia and it is a serious problem both from the perspective of human health and animal husbandry. The widespread appearance of human trichinellosis is attributed to a high prevalence of Trichinella infection in domestic animals, especially swine. Epidemiological data presented in this paper were collected during a 12-year period (1995–2006) at small private swine farms in the region of Branicevo, Serbia where a high Trichinella prevalence in slaughter pigs (0.57%) has been detected. To further monitor Trichinella prevalence in swine, a serological survey, using ELISA, was performed in 2006. Of 916 swine tested by ELISA, Trichinella specific antibodies were detected in 15 (1.64%), while suspect results were obtained in 10 (1.09%). Positive or suspect animals originated from all parishes except one (Pozarevac). Our results point to the need for systematic monitoring in pigs to achieve a better control of trichinellosis in Serbia. 相似文献