Feed Containing Novacq Improves Resilience of Black Tiger Shrimp,Penaeus Monodon,to Gill‐associated Virus‐induced Mortality          下载免费PDF全文

Melony J. Sellars  Min Rao  Nick Polymeris  Simon J. Irvin  Jeff A. Cowley  Nigel P. Preston  Brett D. Glencross 《Journal of the World Aquaculture Society》2015,46(3):328-336

The ability of Novacq to improve resilience of black tiger shrimp, Penaeus monodon, to infection and mortality induced by gill‐associated virus (GAV) was investigated. Over a 26‐d period, shrimp were fed pellets with or without 10% Novacq. Following this, four replicate tanks, each containing 10 shrimp that had been fed either diet, were maintained as‐is, injected with saline or injected with GAV inoculum (i.e., 40 shrimp for each of the six groups). For shrimp (n = 20) in two of each group of four tanks, survival was monitored daily over 14 d and a pleopod was sampled from each shrimp on Days 0 and 14. For the other two tanks, a pleopod was sampled from each shrimp on Days 0, 3, 7, 10, and 14 to track changes in GAV loads over time. Survival was significantly higher (P < 0.05) from Day 7 onward among the group fed Novacq. GAV infection loads appeared to vary more between individuals in the Novacq diet cohort, but overall were not reduced significantly at any time points post‐challenge compared to shrimp tested from the Control diet cohort.  相似文献   

Use of viscoelastic coagulation testing to monitor low molecular weight heparin administration to healthy horses     

Brett S. Tennent‐Brown BVSc  MS  DACVIM  DACVECC  Kira L. Epstein DVM  DACVS  DACVECC  Dorothy D. Whelchel DVM  MS  Steeve Giguère DVM  PhD  DAVCIM 《Journal of Veterinary Emergency and Critical Care》2013,23(3):291-299

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A multicenter retrospective case–cohort study on the prevalence of incisional morbidities in late pregnant mares following exploratory celiotomy (2014–2019): 579 cases     

Chelsea E. Klein DVM  Darko Stefanovski PhD  MS  Alison K. Gardner DVM  MS  DACVS  DACVECC  J. Brett Woodie DVM  MS  DACVS  Rolf M. Embertson DVM  DACVS  Margaret C. Mudge VMD  DACVS  DACVECC  Samuel D. Hurcombe BSc  BVMS  MS  DACVIM  DACVECC 《Journal of Veterinary Emergency and Critical Care》2023,33(1):59-69

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Protein changes in the albedo of citrus fruits on postharvesting storage   总被引：1，自引：0，他引：1  

Lliso I  Tadeo FR  Phinney BS  Wilkerson CG  Talón M 《Journal of agricultural and food chemistry》2007,55(22):9047-9053

In this work, major protein changes in the albedo of the fruit peel of Murcott tangor (tangerine x sweet orange) during postharvest ageing were studied through 2D PAGE. Protein content in matured on-tree fruits and in fruits stored in nonstressing [99% relative humidity (RH) and 25 degrees C], cold (99% RH and 4 degrees C), and drought (60% RH and 25 degrees C) conditions was initially determined. Protein identification through MS/MS determinations revealed in all samples analyzed the occurrence of manganese superoxide dismutase (Mn SOD), actin, ATP synthase beta subunit (ATPase), citrus salt-stress associated protein (CitSap), ascorbate peroxidase (APX), translationally controlled tumor protein (TCTP), and a cysteine proteinase (CP) of the papain family. The latter protein was identified in two different gel spots, with different molecular mass, suggesting the simultaneous presence of the proteinase precursor and its active form. While Mn SOD, actin, ATPase, and CitSap were unchanged in the assayed conditions, TCTP and APX were downregulated during the postharvest ageing process. Ageing-induced APX repression was also reversed by drought. CP contents in albedo, which were similar in on- and off-tree fruits, were strongly dependent upon cold storage. The active/total CP protein ratio significantly increased after cold exposure. This proteomic survey indicates that major changes in protein content in the albedo of the peel of postharvest stored citrus fruits are apparently related to the activation of programmed cell death (PCD).  相似文献   

Color and albedo heterogeneity of Vesta from Dawn     

Reddy V  Nathues A  Le Corre L  Sierks H  Li JY  Gaskell R  McCoy T  Beck AW  Schröder SE  Pieters CM  Becker KJ  Buratti BJ  Denevi B  Blewett DT  Christensen U  Gaffey MJ  Gutierrez-Marques P  Hicks M  Keller HU  Maue T  Mottola S  McFadden LA  McSween HY  Mittlefehldt D  O'Brien DP  Raymond C  Russell C 《Science (New York, N.Y.)》2012,336(6082):700-704

Multispectral images (0.44 to 0.98 μm) of asteroid (4) Vesta obtained by the Dawn Framing Cameras reveal global color variations that uncover and help understand the north-south hemispherical dichotomy. The signature of deep lithologies excavated during the formation of the Rheasilvia basin on the south pole has been preserved on the surface. Color variations (band depth, spectral slope, and eucrite-diogenite abundance) clearly correlate with distinct compositional units. Vesta displays the greatest variation of geometric albedo (0.10 to 0.67) of any asteroid yet observed. Four distinct color units are recognized that chronicle processes--including impact excavation, mass wasting, and space weathering--that shaped the asteroid's surface. Vesta's color and photometric diversity are indicative of its status as a preserved, differentiated protoplanet.  相似文献   

Catalysis and sulfa drug resistance in dihydropteroate synthase     

Yun MK  Wu Y  Li Z  Zhao Y  Waddell MB  Ferreira AM  Lee RE  Bashford D  White SW 《Science (New York, N.Y.)》2012,335(6072):1110-1114

The sulfonamide antibiotics inhibit dihydropteroate synthase (DHPS), a key enzyme in the folate pathway of bacteria and primitive eukaryotes. However, resistance mutations have severely compromised the usefulness of these drugs. We report structural, computational, and mutagenesis studies on the catalytic and resistance mechanisms of DHPS. By performing the enzyme-catalyzed reaction in crystalline DHPS, we have structurally characterized key intermediates along the reaction pathway. Results support an S(N)1 reaction mechanism via formation of a novel cationic pterin intermediate. We also show that two conserved loops generate a substructure during catalysis that creates a specific binding pocket for p-aminobenzoic acid, one of the two DHPS substrates. This substructure, together with the pterin-binding pocket, explains the roles of the conserved active-site residues and reveals how sulfonamide resistance arises.  相似文献   

Taking the "waste" out of "wastewater" for human water security and ecosystem sustainability     

SB Grant  JD Saphores  DL Feldman  AJ Hamilton  TD Fletcher  PL Cook  M Stewardson  BF Sanders  LA Levin  RF Ambrose  A Deletic  R Brown  SC Jiang  D Rosso  WJ Cooper  I Marusic 《Science (New York, N.Y.)》2012,337(6095):681-686

Humans create vast quantities of wastewater through inefficiencies and poor management of water systems. The wasting of water poses sustainability challenges, depletes energy reserves, and undermines human water security and ecosystem health. Here we review emerging approaches for reusing wastewater and minimizing its generation. These complementary options make the most of scarce freshwater resources, serve the varying water needs of both developed and developing countries, and confer a variety of environmental benefits. Their widespread adoption will require changing how freshwater is sourced, used, managed, and priced.  相似文献   

The use of IV lipid emulsion for lipophilic drug toxicities     

Kaplan A  Whelan M 《Journal of the American Animal Hospital Association》2012,48(4):221-227

IV lipid emulsion (ILE) therapy is emerging as a potential antidote for lipophilic drug toxicities in both human and veterinary medicine. ILE has already gained acceptance in human medicine as a treatment of local anesthetic systemic toxicity, but its mechanism of action, safety margins, and standardized dosing information remains undetermined at this time. Experimental and anecdotal use of ILE in the human and veterinary literature, theorized mechanisms of action, current dosing recommendations, potential adverse effects, and indications for use in human and veterinary emergency medicine are reviewed herein.  相似文献   

Compartment syndrome: pathophysiology,clinical presentations,treatment, and prevention in human and veterinary medicine     

Lindsey K. Nielsen DVM  Megan Whelan DVM  DACVECC 《Journal of Veterinary Emergency and Critical Care》2012,22(3):291-302

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Liver lobe torsion in six horses     

BS Tennent-Brown  MC Mudge  J Hardy  DD Whelchel  DE Freeman  AT Fischer 《Journal of the American Veterinary Medical Association》2012,241(5):615-620

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