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51.
van Breugel M Hirono M Andreeva A Yanagisawa HA Yamaguchi S Nakazawa Y Morgner N Petrovich M Ebong IO Robinson CV Johnson CM Veprintsev D Zuber B 《Science (New York, N.Y.)》2011,331(6021):1196-1199
Centrioles are cylindrical, ninefold symmetrical structures with peripheral triplet microtubules strictly required to template cilia and flagella. The highly conserved protein SAS-6 constitutes the center of the cartwheel assembly that scaffolds centrioles early in their biogenesis. We determined the x-ray structure of the amino-terminal domain of SAS-6 from zebrafish, and we show that recombinant SAS-6 self-associates in vitro into assemblies that resemble cartwheel centers. Point mutations are consistent with the notion that centriole formation in vivo depends on the interactions that define the self-assemblies observed here. Thus, these interactions are probably essential to the structural organization of cartwheel centers. 相似文献
52.
Maria G. Chernysheva Ivan Yu. Myasnikov Gennadii A. Badun Dmitry N. Matorin Dilara T. Gabbasova Andrey I. Konstantinov Viktor I. Korobkov Natalia A. Kulikova 《Journal of Soils and Sediments》2018,18(4):1335-1346