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41.
The efficacy of treatment with single dose administration of 5 drugs at different dosages to layer hens naturally infected with Mycoplasma gallisepticum was studied. The drugs were tiamulin, which was administered orally, tylosin (parenterally and orally), spiramycin (orally), long-acting oxytetracycline (parenterally) and tylosindihydrostreptomycin (parenterally). Cure was assessed by the absence of nasal discharge. The cure rate was significantly higher (P less than 0.05) in treated hens than in untreated hens, as early as 1 day after treatment. Remission for 33 days was achieved in 60% of hens treated with 100 mg oxytetracycline, in 100% of hens treated with 100 mg or 200 mg spiramycin, in 92% and 85% of hens treated with 100 mg tylosin, parenterally and orally, and in 89% and 88% of birds given 100 mg tiamulin and tylosin-dihydrostreptomycin, respectively. 相似文献
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43.
G G Duthie J R Arthur S P Simpson F Nicol 《American journal of veterinary research》1988,49(4):508-510
Plasma pyruvate kinase (PK) and creatine kinase (CK) activities were increased significantly (P less than 0.001 and P less than 0.05, respectively) in homozygote halothane-reacting pigs (nn), compared with those activities in homozygote nonreacting pigs (NN). Pyruvate kinase activity was less variable within groups than was CK activity, allowing more effective discrimination between nn and NN geno-types. The PK and CK activities in plasma increase with age in halothane-reacting pigs and the nonreacting pigs. Enzyme activities in heterozygote (Nn) nonreacting pigs did not differ significantly (P greater than 0.05) from enzyme activities of homozygote (NN) nonreacting pigs. Although PK was better than CK in identifying stress-susceptible pigs, age-related effects and the failure to identify heterozygotes may restrict the use of plasma PK activity as a diagnostic test for the stress syndrome. 相似文献
44.
Blood antioxidant status and plasma pyruvate kinase activity of halothane-reacting pigs 总被引:2,自引:0,他引:2
Samples of blood were collected (by jugular venipuncture) from 10 homozygote halothane-reacting pigs and 7 homozygote nonreactors. Antioxidant status was assessed by measurement of blood glutathione peroxidase, glucose-6-phosphate dehydrogenase, and superoxide dismutase activities and plasma concentrations of vitamin E. Significant differences in these values were not apparent between halothane-reacting pigs and nonreactors. Halothane-reacting pigs had tissue damage as indicated by significantly increased plasma activities of the enzymes creatine kinase and pyruvate kinase. The latter showed better discrimination between the 2 populations than did creatine kinase and could prove to be a more effective marker for identification of stress-susceptible pigs. 相似文献
45.
46.
Debra M. Powell MS PhD Karen Bennett-Wimbush MS PhD Amy Peeples AAS BS Maria Duthie BS 《Journal of Equine Veterinary Science》2008,28(1):28-33
To answer the question of whether horse height, cannon bone circumference, and loin width can be used as indicators of weight-carrying ability in light horses, eight mature horses underwent a submaximal mounted standard exercise test under four conditions: carrying 15, 20, 25, or 30% of their body weight. Heart rate was monitored, plasma lactate concentration was determined in jugular blood samples pre-exercise, immediately post-exercise, and 10 minutes post-exercise, with serum creatine kinase activity determined at the same times as plasma lactate concentrations, with additional samples collected at 24 hours and 48 hours post-exercise. Muscle soreness and muscle tightness scores were determined using a subjective scoring system 24 hours before and 24 hours after exercise. Heart rates remained significantly higher when the horses carried 25 and 30% of their body weight. Plasma lactate concentrations immediately and 10 minutes after exercise differed when horses carried 30% of their body weight compared with 15, 20, and 25% weight carriage. Horses tended to have a greater change in muscle soreness and muscle tightness when carrying 25% of their body weight, and a significant change in soreness and tightness scores was found in horses carrying 30% of their body weight. Loin width and cannon bone circumference were found to be negatively correlated to the changes in muscle soreness and tightness scores. In conclusion, the data suggest that horses with wider loin and thicker cannon bone circumference became less sore when carrying heavier weight loads. 相似文献
47.
EOS Batista GG Macedo RV Sala MDDV Ortolan MF Sá Filho TA Del Valle EF Jesus RNVR Lopes FP Rennó PS Baruselli 《Reproduction in domestic animals》2014,49(3):448-452
In Bos taurus cattle, antimullerian hormone (AMH) has been demonstrated to have a high degree of correlation with ovarian antral follicle count and the number of healthy follicles and oocytes. To document the correlation between the plasma concentration of AMH and follicular number in Bos indicus and Bos taurus heifers, Nelore (Bos indicus, n = 16) and Holstein heifers (Bos taurus, n = 16) had their ovarian follicular waves synchronized. After synchronization, ovarian antral follicular population (AFP) was evaluated three times at 60‐day (d) intervals (T‐120 d, 120 days before plasma AMH determination; T‐60 d, 60 days before; and T0, at the time of plasma AMH determination). The plasma AMH concentration was positively correlated with the number of ovarian follicles on the day of the follicular wave emergence in Bos indicus (Nelore) and Bos taurus (Holstein) heifers at each evaluation time (p < 0.05). The AFP was higher in Bos indicus (Nelore) than in Bos taurus (Holstein) heifers (p < 0.05). Similarly, the AMH concentration was higher in Bos indicus (Nelore) than in Bos taurus (Holstein) heifers (p < 0.0001). When heifers were classified as to present high or low AFP according to the mean of the AFP within each genetic group, high‐AFP heifers presented a greater (p < 0.0001) AMH concentration than low‐AFP heifers, regardless of the genetic group. In conclusion, the AFP is positively correlated with plasma AMH concentration in both Bos indicus (Nelore) and Bos taurus (Holstein) heifers. Furthermore, Bos indicus (Nelore) heifers presented both greater plasma AMH concentrations and AFP than Bos taurus (Holstein) heifers. 相似文献
48.
Extraction of phenolics and changes in antioxidant activity of red wines during vinification. 总被引:3,自引:0,他引:3
J Burns P T Gardner D Matthews G G Duthie M E Lean A Crozier 《Journal of agricultural and food chemistry》2001,49(12):5797-5808
The moderate consumption of alcoholic beverages has been associated with protection against the development of coronary heart disease. Although alcohol itself can help prevent coronary heart disease through a number of mechanisms, red wine appears to offer protection above and beyond that attributable to alcohol alone. Red wine is a complex fluid containing grape, yeast, and wood-derived phenolic compounds, the majority of which have been recognized as potent antioxidants. The aim of this study was to investigate the major phenolic contributors to the antioxidant activity of wine. To this end, four wines were followed during the first 7-9 days of vinification. Individual phenolic compounds were quantified by HPLC, and antioxidant activity was determined by electron spin resonance spectroscopy. The extraction of the phenolics was found to be influenced by vinification procedure, grape quality, and grape variety. Although fermenting wines reached a total phenolic content comparable to that of a bottled wine after 9 days of vinification, the antioxidant activity was significantly lower than that of a finished wine. This suggests that the larger polyphenolic complexes and condensation products that appear during aging make a sizable contribution to the overall antioxidant activity of red wines. 相似文献
49.
Mullen W Stewart AJ Lean ME Gardner P Duthie GG Crozier A 《Journal of agricultural and food chemistry》2002,50(18):5197-5201
Scottish-grown red raspberries are a rich source of vitamin C and phenolics, most notably, the anthocyanins cyanidin-3-sophoroside, cyanidin-3-(2(G)-glucosylrutinoside), and cyanidin-3-glucoside, and two ellagitannins, sanguiin H-6 and lambertianin C, which are present together with trace levels of flavonols, ellagic acid, and hydroxycinnamates. The antioxidant capacity of the fresh fruit and the levels of vitamin C and phenolics were not affected by freezing. When fruit were stored at 4 degrees C for 3 days and then at 18 degrees C for 24 h, mimicking the route fresh fruit takes after harvest to the supermarket and onto the consumer's table, anthocyanin levels were unaffected while vitamin C levels declined and those of elligitannins increased, and overall, there was no effect on the antioxidant capacity of the fruit. It is concluded, therefore, that freshly picked, fresh commercial, and frozen raspberries all contain similar levels of phytochemicals and antioxidants per serving. 相似文献
50.
Weta are giant, flightless grasshoppers that are endemic to New Zealand. In the absence of native mammals, weta are thought to perform similar ecological functions. As such, they might be expected to be important seeds dispersers. However, insects are not known to consume fleshy fruits and to disperse seeds after gut passage. We conducted a series of observations and experiments to test whether weta form mutualistic partnerships with fleshy-fruited plants as seed dispersers, similar to small mammals elsewhere in the world. Results showed that weta are indeed effective seeds dispersers, providing an example of ecological convergence between unrelated organisms. 相似文献