An assessment of the status of the common seal Phoca vitulina vitulina in Ireland     

C.F. Summers  P.J. Warner  R.G.W. Nairn  M.G. Curry  J. Flynn 《Biological conservation》1980,17(2):115-123

Common seals Phoca vitulina vitulina Linnaeus 1758 were surveyed throughout Ireland during the 1978 breeding season. Compared with the abundance of the species in Great Britain, the Irish stock is small. The results are discussed in relation to the activities of man, particularly bounty hunting to protect fisheries, and the availability of suitable breeding localities. Problems relating to stock management, not least of which is that the species is subject to legislation in the south but not in the north, are discussed.  相似文献   

Parasites of sheep dogs in the Charleville district, Queensland     

KM CORNACK  PK O'ROURKE 《Australian veterinary journal》1991,68(4):149-149

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Exencephalia: its occurrence in untreated mice     

R J Flynn 《Science (New York, N.Y.)》1968,160(830):898-899

Exencephalia has been reported in irradiated CFI mice but there are no reports of its occurrence in untreated mice of this strain. In the course of establishing disease-free breeding colonies from CFI female mice delivered of their offspring by cesarean section, exencephalia was seen frequently. During a 2-week period, 90 litters were delivered; 11 contained exencephalic fetuses, at the rate of one per litter (11 of 90 litters, 12.2 percent; 11 of 1056 fetuses, 1.04 percent). The prevalence of this anomaly in untreated mice of this strain could contribute to overestimates of the effectiveness of low doses of radiation.  相似文献   

Sequential hair shaft as an indicator of prior mineralization in the Alaskan moose.     

A Flynn  A W Franzmann  P D Arneson 《Journal of animal science》1975,41(3):906-910

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Measurement of creatine kinase MB in canine cardiac patients     

KM WYATT  R. LABUC  GL WYATT 《Australian veterinary journal》1998,76(12):826-826

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Self Assessment     

Lamb CR  Flynn T  Allen C 《The Journal of small animal practice》2005,46(7):357-358

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Evaluation of ameroid ring constrictors for treatment for single extrahepatic portosystemic shunts in dogs: 168 cases (1995-2001)     

Mehl ML  Kyles AE  Hardie EM  Kass PH  Adin CA  Flynn AK  De Cock HE  Gregory CR 《Journal of the American Veterinary Medical Association》2005,226(12):2020-2030

OBJECTIVES: To evaluate use of an ameroid ring constrictor (ARC) for treatment for single extrahepatic portosystemic shunts (PSSs) and identify factors associated with postoperative death, continued portosystemic shunting, and long-term outcome in dogs. DESIGN: Retrospective study. ANIMALS: 168 dogs with a single extrahepatic PSS. PROCEDURE: Medical records of dogs that had a single extrahepatic PSS and were treated with an ARC were reviewed. Signalment, history, clinical signs, results of preoperative blood analyses and portal pressure measurements, PSS location, ARC size, postoperative complications, and postoperative scintigraphy results were recorded. Owners were interviewed 6 months to 6 years after surgery. Results-Postoperative complications developed in 10% of dogs. Postoperative mortality rate was 7.1%. Predictive factors for postoperative death included high preoperative WBC count and postoperative complications. Twenty-one percent of dogs in which portal scintigraphy was performed 6 to 10 weeks after surgery had continued shunting. Predictive factors for persistent shunting included low preoperative plasma albumin concentration, high portal pressure after complete occlusion, and high portal pressure difference (postocclusion minus baseline). Clinical outcome in 108 dogs was classified as excellent (80%), good (14%), or poor (6%). Predictive factors for excellent long-term clinical outcome included high preoperative plasma albumin concentration, low preoperative leukocytosis, low portal pressure after complete occlusion, absence of postoperative seizures, and absence of continued shunting. CONCLUSIONS AND CLINICAL RELEVANCE: Use of an ARC for treatment for a single extrahepatic PSS resulted in low morbidity and mortality rates. Certain preoperative factors were associated with increased risk of postoperative death, continued portosystemic shunting, and long-term outcome.  相似文献   

The Ethics and Role of AI with Fresh and Frozen Semen in Dogs     

GCW England  KM Millar 《Reproduction in domestic animals》2008,43(S2):165-171

The use of artificial insemination (AI) with fresh semen has resulted in many benefits for the management of dog breeding, but there are disadvantages that can sometimes be overlooked. Furthermore, poorer quality semen arising as a result of cryopreservation necessitates uterine insemination, which raises the potential for surgical insemination. A number of significant ethical concerns have been raised by key stakeholders (such as The Kennel Club and the Royal College of Veterinary Surgeons) about AI per se , but particularly about the use of surgical insemination. This paper discusses the technological development of AI and explores a number of the ethical issues raised by its application to dog breeding. An Ethical Matrix method is used to map the potential ethical issues for key interest groups, namely dogs, breeders, owners, veterinarians and wider society. There are national variations in the way in which institutions have evaluated potential ethical impacts, and this is reflected in the different regulatory frameworks governing the use of AI in dogs. In order to facilitate decision-making and reduce some of the ethical risks associated with this technology, the veterinary research community could take several proactive steps including: (i) clarifying clinical decision-making processes, (ii) enhancing informed choice among clients and (iii) increasing the knowledge-base of potential impacts of AI.  相似文献   

Quantification of the DNA Difference,and Separation of X‐ and Y‐Bearing Sperm in Alpacas (Vicugna pacos)     

KM Morton  M Rückholdt  G Evans  WMC Maxwell 《Reproduction in domestic animals》2008,43(5):638-642

Sperm sexing is an emerging reproductive technology which has been successfully used to produce offspring of a pre‐determined sex in domestic and wildlife species but has yet to be applied to New World camelids. The aims of the present study were to (i) optimize the Hoescht 33342 (H33342) staining concentration for the flow cytometric separation of X and Y chromosome‐bearing alpaca (Vicugna pacos) sperm nuclei, (ii) separate alpaca sperm nuclei into high purity (>90%) populations bearing the X‐ and Y‐chromosome and (iii) determine the DNA difference between X‐ and Y‐bearing sperm in alpacas. Semen was collected from alpacas and sperm nuclei stained with H33342, incubated and analysed using a high‐speed cell sorter (SX‐MoFlo^®). H33342 staining concentrations of 36, 54, 72 or 90 μm did not affect the proportion of correctly oriented sperm nuclei (43.3 ± 3.9, 46.4 ± 3.7, 44.5 ± 4.0 and 51.1 ± 2.5% respectively) nor the speed of sorting (1381 ± 160, 1386 ± 123, 1371 ± 133 and 1379 ± 127 sperm nuclei/s). Sort reanalysis determined high levels of purity for X‐ and Y‐enriched populations (96.6 ± 0.7% and 96.1 ± 1.1% respectively). The DNA difference, based on fluorescence intensity (determined by the SX‐MoFlo^®), was 3.8 ± 0.06%. These data demonstrate for the first time that alpaca sperm nuclei can be separated into high purity populations and the potential for applying sperm sexing technology to New World camelids.  相似文献   

Pharmacokinetics of hydroxyzine and cetirizine following oral administration of hydroxyzine to exercised Thoroughbred horses     

Heather K. Knych  Daniel Weiner  Stacy Steinmetz  Katherine Flynn  Daniel S. McKemie 《Journal of veterinary pharmacology and therapeutics》2019,42(6):617-623

Hydroxyzine is a first‐generation antihistamine and cetirizine, a second‐generation antihistamine and active metabolite of hydroxyzine. Hydroxyzine is commonly used in performance horses and as such its use in closely regulated; however, there are no published studies suitable for establishing appropriate regulatory recommendations. In the current study, 12 exercised Thoroughbred research horses received a single oral administration of 500 mg of hydroxyzine. Blood and urine samples were collected prior to and up to 96 hr postdrug administration and concentrations of hydroxyzine and cetirizine determined using liquid chromatography‐tandem mass spectrometry. A joint parent/metabolite population 2‐compartment pharmacokinetic model with first‐order absorption and elimination was utilized to describe the pharmacokinetics of both compounds. Serum hydroxyzine and cetirizine concentrations were above the limit of quantitation (0.1 ng/ml) of the assay at 96 hr (the last time point sampled). The terminal half‐life was 7.41 and 7.13 hr for hydroxyzine and cetirizine, respectively. Findings from this study suggest that a prolonged withdrawal time should be observed if this compound is used in performance administered to performance horses and is classified as prohibited substance by the applicable regulatory body.  相似文献