INDIRECT COMPUTED TOMOGRAPHIC LYMPHOGRAPHY FOR ILIOSACRAL LYMPHATIC MAPPING IN A COHORT OF DOGS WITH ANAL SAC GLAND ADENOCARCINOMA: TECHNIQUE DESCRIPTION          下载免费PDF全文

Stephanie A. Majeski  Michele A. Steffey  Mark Fuller  Geraldine B. Hunt  Philipp D. Mayhew  Rachel E. Pollard 《Veterinary radiology & ultrasound》2017,58(3):295-303

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Anterior-posterior polarity in C. elegans and Drosophila--PARallels and differences     

Pellettieri J  Seydoux G 《Science (New York, N.Y.)》2002,298(5600):1946-1950

The eggs of Caenorhabditis elegans and Drosophila bear little similarity to each other, yet both depend on the par genes for control of anterior-posterior polarity. Here we explore possible common roles for the par genes (pars) in converting transient asymmetries into stably polarized axes. Although clear mechanistic parallels remain to be established, par-dependent regulation of microtubule dynamics and protein stability emerge as common themes.  相似文献   

Amiodarone-induced keratopathy in healthy dogs   总被引：1，自引：0，他引：1  

Bicer S  Fuller GA  Wilkie DA  Yamaguchi M  Hamlin RL 《Veterinary ophthalmology》2002,5(1):35-38

Amiodarone has a broad spectrum as an antiarrhythmic agent and is indicated for patients with atrial and ventricular arrhythmias. Amiodarone-induced corneal deposits are the most common reversible side effect (70-100%) in humans. Additional ocular effects in humans include deposits in the lens, retina and optic nerve. This study was conducted to determine ocular effects of chronic oral amiodarone in healthy dogs. Six chronically amiodarone-treated dogs and four controls were used for this study. Ophthalmic examination was performed using biomicroscopy and indirect ophthalmoscopy at the end of 4th, 7th and 11th weeks when dogs received amiodarone. Corneal microdeposits were observed at the end of the 7th week in one eye and at end of the 11th week in the other eye of one dog. Immediately following euthanasia, corneas and optic nerves were harvested for light and electron microscopic analysis. Light microscopic analysis showed corneal deposits in the basal epithelial cells of the cornea of the clinically affected dog. In addition, a significant increase in basal cell turnover as indicated by mitotic index was observed in the affected dog compared to both nondeposit amiodarone and control groups. All remaining animals were normal. One out of six dogs treated with amiodarone demonstrated corneal deposits (16%). This prevalence is low compared to humans. Explanations for this may include species variations particularly in volume of lacrimal secretion, or the need for longer administration. In addition, sunlight is believed to exacerbate the corneal deposits in humans and all dogs in this study were housed indoors.  相似文献   

Views on euthanasia     

Hale G 《The Veterinary record》2007,160(25):884

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Expression of nonacclimated freezing tolerance and cold acclimation capacity in somatic hybrids between hardy wild Solanum species and cultivated potatoes     

Yu-Kuang H. Chen  Jiwan P. Palta  John B. Bamberg  Heiyoung Kim  Geraldine T. Haberlach  John P. Helgeson 《Euphytica》1999,107(1):1-8

The expression of freezing tolerance was characterized in interspecific somatic hybrids between S. tuberosum (tbr) and two cold-hardy wild species, S. brevidens (brd) and S. commersonii (cmm). The nonacclimated freezing tolerance (NA) and acclimation capacity (ACC, increase in freezing tolerance in response to low nonfreezing temperature), two main genetic components of freezing tolerance, were evaluated separately. In contrast to cmm, which exhibited excellent NA and ACC, the freezing tolerance of brd was mainly due to ACC. However, the ACC of brd was only moderately expressed in the somatic hybrids. The NA of cmm was also suppressed in combination with tbr genomes. However, with acclimation, some of the tbr (+) cmm somatic hybrids achieved freezing tolerance comparable to pure hardy species such as brd used in this study. Analysis of chloroplast DNA type by RFLP markers revealed no significant difference in ACC between somatic hybrids carrying chloroplasts from either tbr or cmm. The reasons for the reduced expression of freezing tolerance from either the brd or cmm parent and the utilization of these somatic hybrids in breeding programs are discussed. This revised version was published online in July 2006 with corrections to the Cover Date.  相似文献   

Where does your food come from?     

Yngve A  Haapala I  Hodge A  McNeill G  Tseng M 《Public health nutrition》2010,13(11):1755-1756

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The fantastic year of 2010--and the really hot topic: breast-feeding     

Yngve A  Tseng M  Hodge A  McNeill G  Haapala I 《Public health nutrition》2010,13(12):1945

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An approach to extrapolate categorical agricultural soil data to nonmapped areas using majority vote     

Christian Böhm  Joachim Kiesel  Detlef Deumlich  Jürgen Thiere 《植物养料与土壤学杂志》2009,172(4):467-476

Soil maps are indispensable base material for planning processes and risk analyses. For many studies, however, area‐wide uniformly scaled soil maps are not available. Our objective was to develop a GIS‐based method for providing information for NoData areas of the Medium‐Scale Agricultural Site Mapping (MMK). NoData areas represent nonagricultural zones, in this case especially forests. A grid‐based methodology for extrapolating soil mapping units of agricultural areas to the entire landscape was developed and tested in Mecklenburg–Western Pomerania (total area 23,170 km²). The principle of the extrapolation method is based on a statistical neighborhood analysis implemented by the moving‐window technology considering selected site features as geology, altitude, and relief energy. Results were illustrated exemplarily for soil‐moisture conditions, which are expressed as “hydromorphy association types”. Four different indicators were derived to ensure a spatially differentiated evaluation of the extrapolation quality. The precision with which it is possible to extrapolate already mapped MMK units in terms of the hydromorphy association type was used to validate the extrapolation method. Evaluation of the results was based on the percentage of Correctly Extrapolated Pixels (CEP), which were derived from a confusion matrix. The percentage of CEP was 26% when the 15 single classes of the hydromorphy association type were considered separately. The percentage of CEP rose up to 65% after grouping the hydromorphy association types into three practically combined categories. It could be demonstrated that the extrapolation technique applied represented an objective and relatively fast and cost‐effective method to obtain an area‐wide MMK mapping.  相似文献   

Cefazolin Concentration in Surgically Created Wounds Treated With Negative Pressure Wound Therapy Compared to Surgically Created Wounds Treated With Nonadherent Wound Dressings          下载免费PDF全文

Julia V. Coutin DVM  Otto I. Lanz DVM  Diplomate ACVS  Geraldine C. Magnin‐Bissel MS  PhD  Diplomate ABT  Marion F. Ehrich MS  RPh  PhD  Diplomate ABT  Emily I. Miller DVM  Diplomate ACVS  Stephen R. Werre PhD  Thomas O. Riegel BA 《Veterinary surgery : VS》2015,44(1):9-16

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Sexual progeny of somatic hybrids between potato andSolanum brevidens: Potential for use in breeding programs     

John P. Helgeson  Geraldine T. Haberlach  Mark K. Ehlenfeldt  Greg Hunt  John D. Pohlman  Sandra Austin 《American Journal of Potato Research》1993,70(6):437-452

Hexaploid somatic hybrids have been obtained by fusion of protoplasts fromSolanum brevidens (PI 218228, 2x = 2n = 24) andS. tuberosum (PI 203900 or cv. Russet Burbank; 2x = 4n = 48). In the work reported here, pentaploid progeny derived from sexual crosses between the somatic hybrids and the potato cultivar, Katahdin were assessed for transfer of disease resistances and improvement of agronomic traits. Segregation was noted in disease resistances to race 0 ofPhytophthora infestans and to tuber soft rot caused byErwinia spp., indicating that sexual transfer of traits captured by protoplast fusion had occurred. The pentaploid progeny showed substantial variation in and often improvement of some agronomic traits as compared to the somatic hybrids. The results indicate that interspecific somatic hybridization can produce material with potential for use in a potato breeding program  相似文献