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51.
52.
A C Hammond G B Huntington R G Breeze 《American journal of veterinary research》1983,44(11):2195-2199
The time course and quantity of 3-methylindole (3MI) and indole absorbed after oral administration of L-tryptophan (TRP) was determined in 2 steers. The relationship between the appearance of 3MI and indole in the rumen and blood plasma to absorption of 3MI and indole was also studied. Two Hereford X Angus steers with portal vein, mesenteric vein, and femoral (steer 1) or iliac (steer 2) artery catheters were used. Absorption rates from the portal drained viscera (net absorption) of 3MI and indole were determined by the product of portal and arterial concentration difference and blood flow. Blood flow was determined by primed continuous infusion of p-aminohippuric acid into a mesenteric vein. Three absorption measurements 30 minutes apart were taken at midpoint times of 0, 12, 24, 36, and 48 hours after oral administration of 0.4 g of TRP/kg of body weight. Steer 1 was dosed twice resulting in a total of 45 absorption measurements. Net absorption of 3MI and indole peaked at an average of 1.05 and 0.81 g/hr, respectively. By 48 hours, 29.2% and 15.3% of the TRP dose were accounted for by 3MI and indole absorption, respectively. Closed system in vitro incubations of TRP with ruminal fluid from the same 2 steers resulted in a TRP to 3MI conversion of 23.2% and a TRP to indole conversion of 10.7%. Net absorption of 3MI and indole closely followed and was correlated with concentration of 3MI and indole in ruminal fluid and blood plasma.(ABSTRACT TRUNCATED AT 250 WORDS) 相似文献
53.
L Maggio-Price C L Emerson T R Hinds F F Vincenzi W R Hammond 《American journal of veterinary research》1988,49(7):1020-1025
Three Beagles with chronic anemia and reticulocytosis were studied. The dogs originated from a large breeding colony and appeared clinically normal with the exception of splenomegaly. The PCV ranged from 30 to 39% (normal, 46 to 56%), with reticulocyte indices of 2.3 to 9.9. Red blood cells were morphologically normal, and examination of marrow aspirates revealed erythroid hyperplasia. Shortened chromium-51 RBC life-spans (7.2 to 15.4 days in anemic dogs; 22.2 to 25.2 days in control dogs) documented a hemolytic anemia. Acquired causes of hemolytic anemia were ruled out. Red blood cells had normal glycolytic enzyme activities, no evidence of unstable or abnormal hemoglobin, and had altered osmotic fragility curves. The breeding of 2 anemic dogs resulted in offspring with anemia and reticulocytosis. Polyacrylamide gel electrophoresis revealed no abnormalities in RBC membrane cytoskeletal proteins in all anemic adult dogs and in 3 offspring. 相似文献
54.
Hammond AL 《Science (New York, N.Y.)》1972,176(4033):391-393
55.
Hammond AL 《Science (New York, N.Y.)》1973,181(4098):428-430
56.
Hammond AL 《Science (New York, N.Y.)》1975,187(4179):823-825
57.
Hammond AL 《Science (New York, N.Y.)》1972,176(4041):1315-1317
58.
59.
L. J. S. Harrison J. A. Hammond M. M. H. Sewell 《Tropical animal health and production》1996,28(1):23-39
Summary The research work relating to helminths, which has been conducted within the Helminthology Section of the CTVM, often in collaboration with colleagues from the tropics is reviewed and placed into a historical perspective. The research has, in the main, concentrated on the trematodesFasciola hepatica andFasciola gigantica and the cestodesTaenia saginata andTaenia solium, but work on other parasites including gastro-intestinal nematodes is also considered. All of these parasites are of obvious veterinary/economic importance particularly in the tropics and subtropics. While the zoonotic importance ofT. saginata andT. solium has been recognised for many years, it is only more recently that the zoonotic impact ofFasciola spp. has been generally acknowledged.
Estudios Sobre Enfermedades Causadas Por Helmintos En El CTVM
Resumen El artículo revisa y sitúa en una perspectiva histórica la investigación sobre helmintos realizada en la sección de helmintología del CTVM, a menudo en colaboración con otros investigadores de países tropicales. La investigación se ha centrado principalmente en los trematodosFasciola hepatica y Fasciola gigantica y en los cestodosTaenia saginata y Taenia solium, aunque en el artículo se incluye también el trabajo realizado con nematodos gastrointestinales y otros parásitos. Todos los parásitos mencionados tienen una importancia obvia desde el punto de vista veterinario y económico, particularmente en los trópicos y subtrópicos. Mientras que la importancia deT. saginata yT. solium como zoonosis ha sido siempre reconocida, el posible carácter zoonótico deFasciola spp. ha sido descubierto muy recientemente.
Etudes Sur Les Helminthiases A CTVM
Résumé Le travail de recherche portant sur les helminthes, qui a été mené dans le groupe Helminthologie à CTVM, souvent en collaboration avec des collègues des pays tropicaux, est passé en revue et mis dans une perspective historique. La recherche a principalement porté sur les trematodesFasciola hepatica etFasciola gigantica et sur les cestodesTaenia saginata etTaenia solium, cependant d'autres travaux ont également porté sur d'autres parasites et sur des nématodes gastro-intestinaux.Tous ces parasites sont d'une importance économique/vétérinaire évidente et ceci particulièrement dans les pays tropicaux et sub-tropicaux. Tandis que l'importance deT. saginata etT. solium, sur la zoonose, a toujours été reconnue, ce n'est que récemment que l'impact deFasciola spp sur la zoonose a été repertorié.相似文献
60.
Hammond AL 《Science (New York, N.Y.)》1973,180(4089):940-941