Hemodynamics in the guinea pig after anesthetization with ketamine/xylazine   总被引：2，自引：0，他引：2  

M V Hart  J R Rowles  A R Hohimer  M J Morton  J D Hosenpud 《American journal of veterinary research》1984,45(11):2328-2330

The resting hemodynamics were determined in 8 guinea pigs after they were anesthetized with ketamine/xylazine. Measurements were made of blood pressure, heart rate, cardiac output, arterial blood gases, and pH. These measurements were obtained initially at 4 to 5 hours after an injection (IM) of ketamine HCl (25 mg) and xylazine (0.15 mg) was given to anesthetize the animals for catheterization (period 1), again 5 days after the operation (period 2), and finally 4 to 5 hours after a 2nd injection of ketamine/xylazine (period 3). There were no differences in heart rates, respiratory rates, or cardiac outputs among the 3 study periods. However, arterial blood pressure was slightly, but significantly, lowered after, and presumably due to, instrumentation (62 +/- 4 mm of Hg, P less than 0.05) when compared with the 5-day postoperative period (67 +/- 7 mm of Hg) or after the readministration of anesthetics (66 +/- 7 mm of Hg). The partial pressure of carbon dioxide in the arterial blood was slightly lower (4 mm of Hg, P less than 0.05) in both acutely postanesthetic periods (period 1 and period 3) than in the same animals at postoperative day 5 (period 2). This study has demonstrated that resting hemodynamics measured shortly after this anesthesia with ketamine/xylazine are not largely different from those in chronically instrumented animals.  相似文献   

ENTEROTOXAMEMIA OF CALVES DUE TO CLOSTRIDIUM WELCHII TYPE E   总被引：1，自引：0，他引：1  

Barry  Hart B.V.Sc. P. T. Hooper  B.V.Sc. 《Australian veterinary journal》1967,43(9):360-363

  相似文献   

Factors governing the toxicity of putative synaptic transmitters and their analogues when injected into the haemocoel of adult male Lucilia sericata     

Richard J. Hart  Charles Potter  Roger G. Wilson 《Pest management science》1977,8(6):722-734

Acetylocholine, arecoline, 2-(dimethylamino)ethyl acetate, L-glutamic acid, L-4-methyl-eneglutamic acid, (±)-quisqualic acid, 4-aminobutyric acid, and dicrotophos were injected into the haemocoel of adult male Lucilia sericata. Large doses of the putative transmitters and their analogues were required for toxicity. The water soluble organo-phosphate dicrotophos was much more toxic than any of the other compounds. Electrophysiological experiments indicated that the putative transmitters were reaching their presumed site of action in the nervous system and that their toxicity could be correlated with the intensity and duration of their effect at this site. Biochemical measurements of the rate of loss of the putative transmitters from the haemolymph indicate that, in vivo, the test insect possesses efficient mechanisms for removing these compounds from the system being studied. It is concluded that the low toxicity of the putative transmitters, which are presumed to interact reversibly with post synaptic receptor sites, may be largely due to their rapid removal from the system, resulting in a rapid fall in concentration at the receptor site.  相似文献   

Behavior of sick animals     

B L Hart 《Veterinary Clinics of North America: Food Animal Practice》1987,3(2):383-391

The behavior of the sick animal is not necessarily a result of physical debilitation; it can be viewed as part of a highly organized adaptive strategy that is at times critical to survival if the animal were living in the wild state. Domestic ruminants appear to have retained this behavioral mode when they are sick. This article brings together several lines of current research about depression, appetite control, and the role of fever in facilitating an animal's ability to combat viral and bacterial infections.  相似文献   

TREATMENT OF DUCK CHOLERA WITH ERYTHROMYCIN     

L. Hart  B.V.Sc.  H.D.A. 《Australian veterinary journal》1963,39(3):92-93

  相似文献   

Aetiology and Endocrinology of Pseudopregnancy in the Goat     

MAM Taverne  JW Hesselink    MM Bevers  HA van  Oord JE Kornalijnslijper 《Reproduction in domestic animals》1995,30(4):228-230

  相似文献   

Probabilistic model for estimating field mortality of target and non-target bird populations when simultaneously exposed to avicide bait     

Johnston JJ  Holmes MJ  Hart A  Kohler DJ  Stahl RS 《Pest management science》2005,61(7):649-659

A probabilistic model was developed to estimate target and non-target avian mortality associated with the application of the avicide CPTH (3-chloro-p-toluidine hydrochloride) to minimize sprouting rice damage in the southern USA. CPTH exposures for individual birds were predicted by random sampling from species-specific non-parametric distributions of bait seed consumption and CPTH residues detected on individual bait seeds. Mortality was predicted from the species-specific exposure versus mortality relationship. Individual variations in this response were captured in the model by Monte Carlo sampling from species-specific distributions of slopes and median toxicity values (LD50) for each bird. The model was used to simultaneously predict mortality (percentage of exposed population and number of birds killed/weight of consumed bait) for a target (blackbird) and non-target (mourning dove) species feeding on bait sites for up to five consecutive days.  相似文献   

Castration of an Asian elephant, using etorphine anesthesia     

M E Fowler  R Hart 《Journal of the American Veterinary Medical Association》1973,163(6):539-543

  相似文献   

Efficacy and safety of a purified porcine insulin zinc suspension for managing diabetes mellitus in dogs     

Monroe WE  Laxton D  Fallin EA  Richter KP  Santen DR  Panciera DL  Towell TL  Williams KA  Hart JR  Hill S  Finkler MR  Shinn JS 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2005,19(5):675-682

The objective of this study was to evaluate the safety and efficacy of a purified porcine insulin zinc suspension for treating dogs with uncomplicated diabetes mellitus. Fifty-three dogs were treated for 60 days after an initial dose determination period. The means of the blood glucose concentrations during 12-hour glucose curves and the means of the blood glucose nadir concentrations during 12-hour glucose curves for all dogs were determined before beginning insulin therapy (time 0), at the end of the dose determination period (time 1), 30 days after time 1 (time 2), and 60 days after time 1 (time 3). Presence of polyuria, polydipsia, and ketonuria was determined at each time point. Adequacy of control of hyperglycemia was based on 12-hour blood glucose curves and improvement in clinical variables (results of physical examinations, historic information, polyuria, polydipsia, and ketonuria). Safety was evaluated by questionnaire, performance of physical examination, CBC, serum chemistry profile, and urinalysis. The means of the blood glucose concentrations during 12-hour glucose curves and the means of the blood glucose nadir concentrations during 12-hour glucose curves for all dogs at times 1, 2, and 3 were significantly lower compared with time 0 (P < .0001). There was a reduction in the proportion of dogs with polyuria, polydipsia, and ketonuria of 82, 86, and 80%, respectively. All of the dogs had adequate glycemic control at time 1, 66% at time 2, and 75% at time 3. At time 3, 66% of dogs required insulin injections q12h. Other than hypoglycemia, there were no important adverse effects of insulin administration. The insulin, was safe and efficacious for reducing blood glucose and clinical signs in dogs with diabetes mellitus.  相似文献   

Comparison of diazepam with progestin for effectiveness in suppression of urine spraying behavior in cats.     

L Cooper  B L Hart 《Journal of the American Veterinary Medical Association》1992,200(6):797-801

The most common treatment for urine spraying and marking in cats has been administration of long-acting progestins. Treatment with diazepam has recently been gaining favor, particularly because of reported adverse effects of progestins. Results of a clinical trial involving 20 cats indicated that diazepam was effective in eliminating or markedly reducing spraying in 11 (55%) of them. However, most cats required continuous treatment, or at least intermittent treatment, when spraying recurred. The physiologic and behavioral dependency of cats on diazepam, which presumably develops over the course of administration, may contribute to the tendency for spraying to recur once diazepam treatment is discontinued. Using data from previously published findings on progestin administration, plus additional cases, it was documented that a significantly (P less than 0.05) higher percentage of males than females responded favorably. Although the number of cases was not sufficient for a statistical comparison of diazepam vs progestin treatment with regard to male vs female, possible gender difference in the effectiveness of diazepam was not indicated.  相似文献