A myopathy of sheep associated with sarcocystis infection and monensin administration     

M Jeffrey  J C Low  A Uggla 《The Veterinary record》1989,124(16):422-426

An outbreak of muscle disease affected approximately 20 of 600 ewes in spring 1987 in south-east Scotland. The clinical signs were a flaccid paralysis of the hind limbs and in severe cases collapse. Serum creatine kinase and aspartate aminotransferase activities were increased. Clinically affected sheep had a mean reciprocal serum antibody titre in a sarcocystis immunofluorescence antibody test of 557 whereas 22 sheep from the same flock, sampled one year earlier, showed a mean reciprocal titre of only 51. Histologically a heavy infestation of sarcocysts, myodegeneration and a non-suppurative myositis centred on degenerating sarcocysts were observed in a wide range of skeletal muscles and myocardium from four affected sheep. Monensin sodium had been inadvertently included in the protein pellet used in the feed for one week before the onset of the disease.  相似文献   

Successful management of severe generalized tetanus in two dogs     

Rochelle M. Low  DVM    Ruth J. Lambert  DVM    S. Anna Pesillo  VMD  DACVECC 《Journal of Veterinary Emergency and Critical Care》2006,16(2):120-127

Objective: To describe the clinical course and successful outcome of severe generalized tetanus in 2 dogs. Case series summary: Two dogs presenting with severe muscle rigidity, opisthotonus, and trismus were diagnosed with tetanus. In both cases, generalized convulsions, respiratory compromise, and autonomic dysfunction necessitated emergent interventions followed by intensive treatment and monitoring. In the second case, transient mechanical ventilation was required. Both dogs survived and were discharged after 19 days (first case) and 18 days (second case) of hospitalization. Although costly and time‐consuming, treatment for severe generalized tetanus was successful in these 2 dogs. New information provided: Severe generalized tetanus with convulsions, respiratory compromise, and autonomic dysfunction can have a successful outcome with intensive care and appropriate treatment.  相似文献   

Reversible versus irreversible renal disease in the dog     

C A Osborne  D G Low  D R Finco 《Journal of the American Veterinary Medical Association》1969,155(12):2062-2078

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Studying the defeated     

Low MF 《Science (New York, N.Y.)》1995,268(5214):1201-1202

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Contact-dependent inhibition of growth in Escherichia coli     

Aoki SK  Pamma R  Hernday AD  Bickham JE  Braaten BA  Low DA 《Science (New York, N.Y.)》2005,309(5738):1245-1248

Bacteria have developed mechanisms to communicate and compete with each other for limited environmental resources. We found that certain Escherichia coli, including uropathogenic strains, contained a bacterial growth-inhibition system that uses direct cell-to-cell contact. Inhibition was conditional, dependent upon the growth state of the inhibitory cell and the pili expression state of the target cell. Both a large cell-surface protein designated Contact-dependent inhibitor A (CdiA) and two-partner secretion family member CdiB were required for growth inhibition. The CdiAB system may function to regulate the growth of specific cells within a differentiated bacterial population.  相似文献   

Emissions of methyl halides and methane from rice paddies     

Redeker KR  Wang N  Low JC  McMillan A  Tyler SC  Cicerone RJ 《Science (New York, N.Y.)》2000,290(5493):966-969

Methyl halide gases are important sources of atmospheric inorganic halogen compounds, which in turn are central reactants in many stratospheric and tropospheric chemical processes. By observing emissions of methyl chloride, methyl bromide, and methyl iodide from flooded California rice fields, we estimate the impact of rice agriculture on the atmospheric budgets of these gases. Factors influencing methyl halide emissions are stage of rice growth, soil organic content, halide concentrations, and field-water management. Extrapolating our data implies that about 1 percent of atmospheric methyl bromide and 5 percent of methyl iodide arise from rice fields worldwide. Unplanted flooded fields emit as much methyl chloride as planted, flooded rice fields.  相似文献   

Osmoregulation in the mudskipper,Boleophthalmus boddaerti II. transepithelial potential and hormonal control     

C.G.L. Lee  W.P. Low  T.J. Lam  A.D. Munro  Y.K. Ip 《Fish physiology and biochemistry》1991,9(1):69-75

Boleophthalmus boddaerti submerged in 10%, 50% and 80% seawater (sw) for 7 days, had whole body transepithelial potentials (TEP) of 3.3, 18.3 and 22.9 mV, respectively. Hypophysectomy significantly decreased the TEP ofB. boddaerti and reversed the polarity of the TEP of the fish exposed to 10% sw.Hypophysectomy also significantly decreased the branchial Na⁺-K⁺ activated adenosine triphosphatase (Na⁺,K⁺-ATPase) activity but increased the activity of branchial HCO₃ ^–-Cl^– stimulated adenosine triphosphatase (HCO₃ ^–,Cl^–-ATPase) inB. boddaerti exposed to 10% sw. However, survival in 10% sw was not significantly impaired by hypophysectomy and no significant change in plasma osmolality and plasma Na⁺ and Cl^– concentrations was observed.Various doses of ovine-prolactin or salmon-prolactin were unable to restore the TEP of hypophysectomizedB. boddaerti in 10% sw to that of the sham-operated fish. However, cortisol increased TEP to a positive value in hypophysectomizedB. boddaerti, though it was still lower than the sham-operated control. Cortisol treatment also affected the plasma osmolality, plasma Na⁺ and Cl^– contents and branchial Na⁺,K⁺-ATPase and HCO₃ ^–,Cl^–-ATPase activities. Overall, the hormonal control of osmoregulation inB. boddaerti appeared to differ from that of other teleosts.  相似文献   

A field trial of ovine enzootic abortion vaccine     

K A Linklater  J C Low  B D Hosie 《The Veterinary record》1987,121(13):303-304

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Characterization of three infectious bronchitis virus isolates from China associated with proventriculus in vaccinated chickens.   总被引：1，自引：0，他引：1  

L Yu  Y Jiang  S Low  Z Wang  S J Nam  W Liu  J Kwangac 《Avian diseases》2001,45(2):416-424

Outbreaks of an avian disease in infectious bronchitis-vaccinated chickens in China have led to the characterization of coronaviral isolates Q1, J2, and T3, which were isolated from proventricular tissues of the affected young layer flocks. Serologic analysis revealed that they could induce high titers of infectious bronchitis virus (IBV) antibodies in inoculated specific-pathogen-free (SPF) chickens in indirect enzyme-linked immunosorbent assay but were not neutralized by antisera specific to the IBV serotype M41 and the Australian T strain. In a pathogenicity experiment, the clinical signs and related gross lesions resembling those of field outbreaks were reproduced in SPF chickens, and viruses were reisolated from the damaged tissues, including trachea, proventriculus, duodenum, and cecal tonsil. Sequence data demonstrated the complete S1 amino acid sequences of these isolates were almost identical despite recovery from geographically different areas in China and had 47.3%-82.3% similarity in comparison with the 47 published S1 sequences. On the basis of genotyping and limited serology, the three isolates, which were responsible for field outbreaks of the disease, might be a new IBV variant.  相似文献   

Reactions of gaseous pollutants with solids     

M. J. D. Low  P. L. Lee 《Water, air, and soil pollution》1973,2(1):61-73

Infrared spectra were recorded of CH₃OH, C₂H,₅OH, HCOOH, CH₃COOH, CH₃COOC₂H₅, (C₂H₅)₂O, CH₃CHO, CH₃CHCHCHO, and CH₃CHCHCOOH sorbed on MgO powder at 25°. In addition to being physically adsorbed, all adsorbates reacted extensively with the surfaces. There was a general trend for the chemisorbed species to form surface carboxylates.  相似文献