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61.
A haematological disorder in a dog characterised by a massive leucocytosis, mainly composed of eosinophils and their precursors is reported here. The normal composition of cells in the bone marrow was displaced in favour of the eosinophils and their precursors. No apparent cause for the pronounced eosinophilia could be determined by clinical, haematological, clinical-chemical, radiological or pathological examinations. A diagnosis of eosinophilic leukaemoid reaction was suggested as the criteria for the diagnosis of eosinophilic leukaemia in the dog but this was not firmly established. 相似文献
62.
Heat production, which accounts for 0.6 of gross energy intake, is insufficiently represented in predictions of food intake. Especially when heat production is elevated (for example by lower temperature or poor feathering) the classical predictions based on body weight, body-weight change and egg mass are inadequate. Heat production was reliably estimated as [35.5-environmental temperature (degree C)] x [Defeathering (=%IBPW) + 21]. Including this term (PHP: predicted heat production) in equations predicting food intake significantly increased accuracy of prediction, especially under suboptimal conditions. Within the range of body weights tested (from 1.6 kg in brown layers to 2.8 kg in dwarf broiler breeders), body weight as an independent variable contributed little to the prediction of food intake; especially within strains its effect was better included in the intercept. Significantly reduced absolute values of residual food consumption were obtained over a wide range of conditions by using predictions of food intake based on body-weight change, egg mass, predicted heat production (PHP) and an intercept, instead of body weight, body-weight change, egg mass and an intercept. 相似文献
63.
Pharmacokinetic and Phase I Evaluation of Carboplatin in Dogs 总被引:1,自引:1,他引:0
Rodney L. Page DVM MS Margaret C. McEntee DVM Steven L. George PhD Patrick L. Williams PhD Greta L. Heidner DVM Carol A. Novotney DVM Jim E. Riviere DVM PhD Mark W. Dewhirst DVM PhD Donald E. Thrall DVM PhD 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》1993,7(4):235-240
Thirty dogs with spontaneously occurring malignant neoplasms were treated monthly with carboplatin (CBDCA) given as a 30-minute intravenous infusion in a dose escalation study. Twenty-eight dogs were considered evaluable for toxicity. The maximally tolerated dose of CBDCA was conceptually defined as that dose, determined by logistic regression analyses of toxicity data, resulting in a 50% incidence of moderate toxicity (MOD50) or a 5% incidence of severe toxicity (SEV5). Each designated maximally tolerated dose was calculated for the first course of treatment only and for the first and second courses of treatment combined to estimate cumulative drug toxicity. The MOD50 and SEV5 for the first treatment course were 340 and 278 mg/M2, respectively. MOD50 and SEV5 values for the first plus second treatment courses were 327 and 231 mg/M2, respectively. The nadir of neutrophil and platelet counts occurred approximately 14 days after treatment. The mean neutrophil and platelet values for all dogs experiencing myelosuppression during the first two treatment courses were 1541/μL and 62,600/μL, respectively. Nonparametric pharmacokinetic analysis of plasma CBDCA values suggested that half-life (T1/2), area-under-the-curve and total body clearance (CLb) were not dose dependent. Volume of distribution (VDss) significantly increased with dose only between 100 and 150 mg/M2, not between 150 and 300 mg/M2. Dose-independent serum CBDCA pharmacokinetic disposition indicates that detailed investigation of tissue CBDCA distribution would be warranted and may identify novel dosing strategies that could improve the therapeutic index of CBDCA by minimizing toxicity. (Journal of Veterinary Internal Medicine 1993; 7:235–240. Copyright © 1993 by the American College of Veterinary Internal Medicine.) 相似文献
64.
Anatomy of the digestive tract and external body development during the embryonic stages of the caprine (Copra, bircus) The purpose of this work has been to establish the pattern of prenatal growth and normal development of the digestive tract and annex glands during goat embryonic stages. 21 embryos with ages ranging from 14 to 34 days (1.69 to 5.90 cm CR) as determined by registering the mating time, were obtained by cesarea. This material was histologically processed to obtain complete serial sections of the stomatodaeum, foregut, midgut, hindgut and cloaca. In this work, it is chronologically described the morphogenesis and histogenesis of the mouth, hypophysis, pharynx and its derivatives, stomach, intestine, liver, pancreas and cloaca. The results obtained establish chronological comparisons with the development of the lamb and gives information on the unitary origin of the gastric compartments in ruminants. 相似文献
65.
Barry O. Hughes 《British poultry science》1993,34(3):625-626
Poultry Health and Management: Chickens, Ducks, Turkeys, Geese, Quail, 3rd edn. By David Sainsbury, 1992. 214 pp., illustrated. Oxford, Blackwell Scientific Publications. £17.99. ISBN 0–632–03325–8. 相似文献
66.
Mitchell A. Crystal DVM Dominique G. Penninck DVM Michael E. Matz DVM Susan H. Pearson BA Greg O. Freden DVM Richard M. Jakowski DVM 《Veterinary radiology & ultrasound》1993,34(6):438-444
The purpose of this study was to evaluate the usefulness of ultrasound-guided fine-needle aspiration biopsy and core biopsy in the diagnosis of infiltrative gastrointestinal diseases. Six dogs and seven cats with clinical signs of gastrointestinal disease underwent ultrasonography and intestinal lesions were identified. One or more ultrasound-guided fine-needle aspiration biopsy and/or core biopsy procedures were performed in each patient. Each patient also underwent one of the following additional procedures for comparison of results: 1) surgery (n=4), 2) endoscopy (n=2), 3) post mortem exam (n=3), and, 4) for lymphoma diagnosed with ultrasound-guided procedures, response to chemotherapy (n=4). Correct diagnoses were obtained in nine of the 13 patients, incorrect diagnoses in two of the 13 patients, and inconclusive diagnoses in two of the thirteen patients. Of the 16 total ultrasound-guided procedures performed, ten were confirmed as correct, three as incorrect, and three were non-diagnostic. Intestinal lesions with bowel wall thickness greater than 2.0 cm had a higher percentage of correct diagnoses than lesions of lesser wall thickness. Gastric lesions had a higher percentage of correct diagnoses than small and large intestinal lesions. Malignant lesions had a higher percentage of correct diagnoses than benign lesions. There were no complications. Ultrasound-guided gastrointestinal fine-needle aspiration biopsy and core biopsy appears to be a safe, accurate, and rapid procedure for use in the diagnosis of infiltrative gastrointestinal disease. 相似文献
67.
Mark G Papich 《Veterinary Clinics of North America: Equine Practice》2003,19(3):645-63, vi
Antibiotics will always be needed in horses for many types of infections, but the adverse consequences also must be considered. For the conditions described in this article, there is justification for antibiotic therapy. The intestinal problems that antibiotics can induce are among the risks from their administration to horses. Disruption of the endogenous bacterial population, colitis, and diarrhea are the most common complications from antibiotic therapy. 相似文献
68.
69.
猪、禽日粮的传统赖氨酸添加源是盐酸L 赖氨酸。但是 ,如今有了另一种赖氨酸源 ,这种新赖氨酸源在经济上可比传统的盐酸L 赖氨酸更为合算。这种新赖氨酸源是一种干燥的颗粒状产品 ,其中含硫酸L 赖氨酸和发酵副产品 ,由谷氨酸棒状杆菌(Corynebacteriumglutamicum)发酵产生 ,产地为美国内布拉斯加州。其商品成品提供 60 %盐酸L 赖氨酸的赖氨酸替代值。此外 ,其发酵副产品还含有盐酸L 赖氨酸中不含的其它氨基酸、磷和能量 (表 1 )。美国已用猪和肉鸡对其进行了硫酸L 赖氨酸和盐酸L 赖氨酸的比较试验。最近在美… 相似文献
70.
The influence of an eradication programme for lice on the prevalence of light flecks and spots on cattle hides was studied in 33 dairy cattle herds during a period of two and a half years. Lice were eradicated from the main group of herds after 9 to 12 months and the quality of the hides before and after treatment was compared. Hides from slaughtered animals were collected during the study period, tanned and examined with special emphasis on the occurrence of the grain damage light flecks and spots. The prevalence of hides without light flecks and spots increased from 24.2% before treatment to 61.6% after treatment. The prevalence of hides free from the damage increased significantly in all examined anatomical regions. The improvement in hide quality was most marked in the shoulders and neck region which corresponded to the major predilection site of cattle lice. The prevalence of hides with light flecks and spots started to decrease in the first period (2-40 days) after eradication. The changes after treatment suggested that most healing process took place over a period of about 4 months. The eradication programme eliminated the seasonal variation in the prevalence of light flecks and spots which was present before treatment. 相似文献