Localized parakeratotic hyperkeratosis in sixteen Boston terrier dogs          下载免费PDF全文

Fiona F. Lee  Charles W. Bradley II  Christine L. Cain  Stephen D. White  Catherine A. Outerbridge  Lisa A. Murphy  Elizabeth A. Mauldin 《Veterinary dermatology》2016,27(5):384-e96

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Viral testing of 18 consecutive cases of equine serum hepatitis: A prospective study (2014‐2018)     

Joy E. Tomlinson  Amit Kapoor  Arvind Kumar  Bud C. Tennant  Melissa A. Laverack  Laurie Beard  Katie Delph  Elizabeth Davis  Harold Schott II  Kara Lascola  Todd C. Holbrook  Philip Johnson  Sandra D. Taylor  Erica McKenzie  Jessica Carter‐Arnold  Emilie Setlakwe  Lisa Fultz  Jeff Brakenhoff  Rebecca Ruby  Sheetal Trivedi  Gerlinde R. Van de Walle  Randall W. Renshaw  Edward J. Dubovi  Thomas J. Divers 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2019,33(1):251-257

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Spasmolytic stilbenoids from Maxillaria densa     

Estrada S  López-Guerrero JJ  Villalobos-Molina R  Mata R 《Fitoterapia》2004,75(7-8):690-695

2,5-dihydroxy-3,4-dimethoxyphenanthrene (1), fimbriol-A (2), nudol (3), gymnopusin (4) and erianthridin (5) isolated from Maxillaria densa provoked a concentration-dependent inhibition of the spontaneous contractions of the rat ileum with potencies comparable to papaverine. In order to establish the mode of action of stilbenoids 1-5, their effect on the contractions induced by different spasmogens (histamine, barium chloride and L-NAME) was investigated. In general, the results suggested that the relaxant activity of the products does not involve a direct nitrergic or antihistaminergic mode of action or an interference with calcium influx into the smooth muscle cells.  相似文献   

Mitigation of effects of extreme drought during stage III of peach fruit development by summer pruning and fruit thinning     

Lopez G  Mata M  Arbones A  Solans JR  Girona J  Marsal J 《Tree physiology》2006,26(4):469-477

A water deficit during stage III of fruit growth was established with the aim of determining if it is possible to achieve an improvement in tree water status by summer pruning and fruit thinning. The experiment was set up as a randomized block split-plot design across trials (irrigation) where pruning was assigned to the main plot and fruit thinning to the sub-plots. The irrigation treatments were (1) standard full irrigation (FI), and (2) suppression of irrigation during stage III of fruit growth until leaves visibly withered (LWI); the pruning treatments were (1) experimental summer pruning (EP), and (2) standard summer pruning (CP); and three fruit thinning intensities were applied to facilitate analysis of the effects of the treatments in relation to fruit load. Changes in amount of light intercepted and in tree stem water potential (Psi stem) were evaluated. The EP treatment reduced the amount of light intercepted by the tree. In the FI treatment, there was a significant reduction in fruit growth measured as both water accumulation and dry mass accumulation. Under FI conditions, reductions in fruit load as a result of EP were not accompanied by a significant improvement in Psi stem. In the LWI treatment, EP produced a significant improvement of 0.17 MPa in Psi stem, but there was no improvement in fruit growth compared with CP trees. A reduction in fruit load from 350 (commercial load) to 150 per tree significantly improved Psi stem by 0.3 MPa at the end of stage III of fruit growth. These results indicate that improvements in water status in response to pruning may be insufficient to promote fruit growth if the pruned trees are unable to provide an adequate supply of assimilates to the developing fruits.  相似文献   

Effect of Several Antioxidants on Thawed Ram Spermatozoa Submitted to 37°C up to Four Hours     

M Mata‐Campuzano  M Álvarez‐Rodríguez  M Álvarez  L Anel  P de Paz  JJ Garde  F Martínez‐Pastor 《Reproduction in domestic animals》2012,47(6):907-914

Thawed ram spermatozoa were incubated at 37°C in the presence of dehydroascorbic acid (DHA), TEMPOL (TPL), N‐acetyl‐cysteine (NAC) and rutin (RUT), at 0.1 and 1 mm , in order to test their effects on sperm physiology. Cryopreserved spermatozoa from four rams were thawed, pooled, washed and incubated in TALP‐Hepes with 1 mm or 0.1 mm of each antioxidant, performing a replicate with induced oxidative stress (Fe²⁺/ascorbate). Motility (CASA), viability and mitochondrial membrane potential (flow cytometry) were analysed at 2 and 4 h. Lipoperoxidation (MDA production), intracellular reactive oxygen species (ROS) and DNA status (TUNEL) were analysed at 4 h. Antioxidants, except DHA 0.1 mm , decreased motility and kinematic parameters, but had little effect on viability or mitochondrial activity. Except 1 mm DHA, the antioxidants reduced ROS at 4 h. Moreover, NAC 1 mm , rutin and TEMPOL reduced ROS and DNA damage in the presence of oxidative stress. N‐acetyl‐cysteine, rutin 1 mm and TEMPOL reduced lipoperoxidation in the presence of oxidative stress. However, DHA did not affect lipoperoxidation. At 1 mm , DHA increased DNA damage in the absence of oxidative stress. Dehydroascorbic acid effects could arise from spermatozoa having a low capacity for reducing it to ascorbic acid, and it may be tested in the presence of other antioxidants or reducing power. Future research should focus in testing whether the inhibition of motility observed for NAC, rutin and TEMPOL is reversible. These antioxidants might be useful at lower temperatures (refrigerated storage or cryopreservation) when their protective effects could be advantageous.  相似文献   

Nd:YAG Laser Treatment of a Vestibulovaginal Varicosity in a 15-Year-Old Pregnant Mare     

Catherine DeLuca  John J. Dascanio  Douglass B. Berry II 《Journal of Equine Veterinary Science》2007

A 15-year-old, pregnant Dutch Warmblood mare was exhibiting intermittent hemorrhage secondary to a large vestibulovaginal varicosity. The vessel was reduced with transendoscopic Nd:YAG laser photocoagulation. This technique is minimally invasive compared with traditional surgical ligation, and significantly decreases the risk of severe hemorrhage, especially with advancing pregnancy. One laser treatment resulted in complete reduction in vessel size and allowed the pregnancy to continue to term without incident or further vaginal hemorrhage.  相似文献   

NAB 365, a beta 2-receptor sympathomimetic agent: clinical experience in horses with lung disease   总被引：2，自引：0，他引：2  

II. L. SASSE  R. HAJER 《Journal of veterinary pharmacology and therapeutics》1978,1(3):241-244

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IMAGING DIAGNOSIS—OCCIPITOATLANTOAXIAL MALFORMATION IN A MINIATURE HORSE FOAL     

Diana S.  Rosenstein  DVM  MS  Harold C.  Schott II  DVMP hD  Russ L.  Stickle  DVM 《Veterinary radiology & ultrasound》2000,41(3):218-219

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A Genome-Wide Association Study for Morphometric Traits in Quarter Horse     

Camila Tangari Meira  Michel Marques Farah  Marina R.S. Fortes  Stephen S. Moore  Guilherme L. Pereira  Josineudson Augusto II V. Silva  Marcílio Dias S. da Mota  Rogério Abdallah Curi 《Journal of Equine Veterinary Science》2014

A genome-wide association study for morphometric traits was conducted in 184 Quarter Horses, 120 from a racing population, and 64 from a cutting population, which were genotyped using the Illumina EquineSNP50 chip. Association analysis was performed with 42,058 single-nucleotide polymorphisms (SNPs) (after quality control) using Qxpak5 software. The following traits were measured: weight (W), rump length (RL), and body length (BL). These morphometric traits are important for the best performance in race and cutting events. For weight, three SNPs associated (P < .0001) were found on chromosomes (Equus caballus autosomes [ECA]) 2 and 3. For rump length, eight SNPs associated (P < .0001) were found on ECA 2, 3, 6, 7, 9, 21, and 26. On ECA 3 and ECA 8, two SNPs were associated (P < .0001) with body length. So, a total of 13 important chromosomal regions were identified with Q values of 0.53 (SNPs for W), 0.40 (SNPs for RL), and 0.99 (SNPs for BL). Positional and functional candidate genes emerging from this study were WWOX and AAVPR1A. Further studies are required to confirm these associations in other populations.  相似文献   

Sustainability of regulated deficit irrigation in a mid-maturing peach cultivar     

Jordi Marsal  Jaume Casadesus  Gerardo Lopez  Merce Mata  Joaquim Bellvert  Joan Girona 《Irrigation Science》2016,34(3):201-208

The level of irrigation restriction to apply in a deficit irrigation (DI) programme for sustainable peach (‘Baby gold 6’) production was investigated. The experiment involved four irrigation treatments over five consecutive seasons (2007–2011). They were full irrigation (control), reducing irrigation by 20 % during the first half of stage III (DI-80 %), withholding irrigation until reaching a light stress level (DI-L) and withholding irrigation until reaching a moderate stress level (DI-M). The withholding of irrigation in both DI-L and DI-M was applied only during stage II and postharvest periods and was based on midday stem water potential thresholds (Ψ _stem). For the DI-L treatment ?1.5 MPa was used in both periods, and for DI-M ?1.8 and ?2.0 MPa were used during stage II and postharvest, respectively. Average Ψ _stem values during DI periods were approximately ?1.4 and ?1.2 MPa for DI-M and DI-L, respectively. The pre-defined thresholds required to trigger irrigation were rarely reached. No significant differences between treatments were found in terms of yield in any experimental year. However, DI-M and to a lesser extent DI-L had lower final fruit fresh mass at harvest related to lower Ψ _stem after three consecutive years of the experiment (during 2010 and 2011). Therefore, in terms of fruit size, DI was not sustainable. Rather than lowering Ψ _stem thresholds, we recommend discontinuing DI after 3-year application.  相似文献