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101.
102.
Mohamad Zamani-Ahmadmahmudi Maziar Jajarmi Saeedeh Talebipour 《Veterinary and comparative oncology》2023,21(1):73-81
Canine mammary gland tumours (CMTs) constitute the most common cancer in female dogs and comprise approximately 50% of all canine cancers. With the advent of high-throughput technologies such as microarray and next-generation sequencing, the molecular phenotyping (classification) of various cancers has been extensively developed. The present study used a canine RNA-sequencing dataset, namely GSE119810, to classify 113 malignant CMTs and 64 matched normal samples via an unsupervised hierarchical algorithm with a view to evaluating the association between the resulting subtypes (clusters) (n = 4) and clinical and molecular characteristics. Finally, a molecular classifier was developed, and it detected 1 high-risk molecular subtype in the training dataset (GSE119810) and 2 independent validation datasets (GSE20718 and GSE22516). Our results revealed four molecular subtypes (C2–C5) in malignant CMTs. Furthermore, the normal samples constituted a distinct group in the clustering analysis. Marked significant associations were observed between the molecular subtypes (especially C5) and clinical/molecular features, including positive lymphatic invasion, high tumour grades, histopathology diagnoses, short survival and high TP53 mutation rates (ps <.05). The high-risk subtype (C5) was further characterized through the development of a cell cycle-based gene signature, which comprised 37 proliferation-related genes according to the support vector machine algorithm. This signature identified the high-risk group in both training and validation datasets (ps <.001). In the validation analysis, our potential classifier robustly predicted patients with positive lymphatic invasion, metastases and short survival. 相似文献
103.
Tanaka Kenzo Reiji Yoneda Mohamad Alias Azani Nik Muhamad Majid 《Journal of Forest Research》2008,13(2):137-142
Leaf hairs may assist in maintaining high leaf water use efficiency in tropical secondary forest tree species. We compared
leaf temperature, transpiration, photosynthesis and water use efficiency between hairy and depilated leaves in Mallotus macrostachyus (Euphorbiaceae), to determine the role of leaf hair in leaf water use efficiency (WUE) in tropical degraded secondary forest
in Malaysia. Measurements were made on five mature individuals growing in sun-exposed conditions and five in shaded conditions.
The hair dry weight per unit leaf area was significantly greater in sun leaves than in shade leaves. The transpiration rate
(Trmax) of depilated leaves in sun-exposed conditions was slightly higher than in hairy leaves in both morning and afternoon measurements.
In contrast, Trmax in the shade leaves was almost identical in hairy and depilated leaves. Leaf stomatal conductance (g
s) in the morning showed almost the same value among leaf types and light conditions. In the afternoon, g
s slightly decreased from the morning values in both sun and shade conditions. In the morning, the leaf water use efficiency
(A
max/Trmax) in both conditions did not differ significantly between hairy and depilated leaves. However, in the afternoon, WUE in the
depilated leaves was significantly lower than in hairy leaves in sun-exposed conditions. These observations suggest that leaf
hairs in M. macrostachyus contribute to the high leaf water use efficiency in drought conditions, such as high vapor pressure deficit experienced at
midday in degraded tropical secondary forests. 相似文献
104.
Optimization of Enzymatic Protein Hydrolysis from Cobia (Rachycentron canadum) Frame Using Alcalase®
Mat Amin Amiza Jasmin Mohamad Rosly Hasan 《Journal Of Aquatic Food Product Technology》2013,22(3):303-312
The combined effects of hydrolysis time, temperature, pH, and ratio of enzyme to substrate on the degree of hydrolysis (DH) of cobia frame were determined using Response Surface Methodology. The effects of these factors were employed using a three-level factors face-centered central composite design. The proximate compositions of cobia frame and cobia hydrolysate powder were determined as well. The generated model equation gave a quadratic fit with experimental data. It is suggested that hydrolysis conditions for obtaining the optimum DH using Alcalase® were: temperature of 58°C, hydrolysis time of 134 min, pH of substrate at 9.4, and an enzyme concentration of 8.3%. Proximate analyses revealed that cobia frame contained 47.0% protein, 27.6% fat, and 24.8% ash; whereas cobia frame hydrolysate powder contained 88.8% protein, 0.58% fat, and 5.05% ash. The high protein content indicated that cobia frame hydrolysate is a potential ingredient for food and feed. 相似文献
105.
M. M. Marliana Azman Hassan M. Y. Nor Yuziah H. P. S. Abdul Khalil I. M. Inuwa M. I. Syakir M. K. Mohamad Haafiz 《Fibers and Polymers》2016,17(6):902-909
Unsaturated polyester (UP) resin has been blended with phenolic resin (PF) resole type at various ratios to obtain a homogeneous blend with improved flame resistance compared to its parent polymers. The polymer blend was reinforced with 20 wt% kenaf using hand lay out technique. Fourier transform infrared spectroscopy (FT-IR) was used to characterize changes in the chemical structure of the synthesized composites. The thermal properties of the composites were investigated using thermogravimetric analysis (TGA). The thermal stability of UP/PF kenaf composites co-varies with the PF content, as shown by the degradation temperature at 50 % weight loss. The char yield of the composites increases linearly with PF content as shown by the TGA results. The flammability properties of the composites were determined using the limiting oxygen index (LOI) and UL-94 fire tests. The LOI increased with the PF content while the composites exhibit improved flame retardancy as demonstrated by UL-94 test. The mechanical and morphological properties of the composites were determined by tensile test and scanning electron microscopy (SEM), respectively. The tensile strength and the Young’s modulus of the blend/composites slightly decreased with increasing PF content albeit higher than PF/kenaf fiber composites. 相似文献
106.
Farah Najihah Razali Noraznawati Ismail Ahmad Fisal Tuan Chilek Tuan Zainazor Faridah Mohamad Ahmad Shamsuddin 《Aquaculture Research》2020,51(4):1523-1532
The aquafeed development has been initiated for horseshoe crabs in captivity. However, much of the attentions were to the juveniles for their widely used in research. Until recently, the research had incorporated the adult horseshoe crabs. This study aims to 1) determine the best alternative feeds for adult males of Carcinoscorpius rotundicauda, 2) measure the acceptance rate of feed, and 3) feeding utilization. Three semi‐moist pellets were either developed or purchased: fish (Decapterus russeli) and cockle (Anadara granosa) pellets (A), fish pellets (B) and keropok pellets (C). Natural feeds act as control: cockle, Anadara granosa (D) and fish, D. russeli (E). The horseshoe crabs were fed daily for 5 weeks and were analysed on their feed percentage consumption, body weight changes, feeding rate (FR), absorption efficiency (AE), feeding conversion ratio (FCR) and specific growth rate (SGR). Feed A was consumed the most (56.21%) with the highest FR (1.88%). It was influenced by the pellet's hardness, where horseshoe crabs favoured softer pellets. Body weight changes, FCR and SGR also showed a similar trend of favouring alternative feed over natural feed. Alternative feeds served a better feed than the natural feed and can be an option for future natural feed replacement for adult horseshoe crabs in captivity. Alternative feed served a better diet than the natural feed and Feed B served the best feed among the three alternative feeds with good C. rotundicauda growth performance and the feed itself is cost‐wise. 相似文献
107.
The growth and morphological development including fins, spine distribution and pigmentation of larval and juvenile of hatchery‐reared yellow puffer, Chonerhinos naritus were described to provide essential information on the early life history of this species. The total length (TL) of newly hatched larvae was 3.42 ± 0.23 (mean ± SD) mm, reaching 5.66 ± 0.38 mm on 5 days after hatched (DAH), 7.80 ± 0.28 mm on 11 DAH, 9.88 ± 0.40 mm on 27 DAH and 10.92 ± 0.58 mm on 30 DAH. The yolk was completely absorbed in preflexion larvae at 4 DAH. The mouth opening started at 3 DAH of yolk sac larvae, while the teeth appeared starting from preflexion larvae at 7 DAH. Overall aggregate fin ray numbers including caudal fin attained full complement in postflexion larvae at 27 DAH. Several melanophores with appearance of small stellate were first appeared dorsally on the head of flexion larvae at 13 DAH, expanded at the dorsal region of the head, above the eye in juveniles at 30 DAH. The spines first appeared in preflexion larvae of C. naritus at 7 DAH, covering the ventral skin region below pectoral fin base and expanded to the ventral part of the body and nearly covered the whole abdomen region before the anus and below the eyes in juveniles. C. naritus remain as larvae for approximately 29 days, during which they metamorphose to the juvenile stage prior to sexual maturation. Observations in larvae development of C. naritus revealed similar characteristics with other Tetraodontidae species. 相似文献
108.
A 60-day feeding experiment was carried out on juvenile Iranian sturgeon (Acipenser persicus) to evaluate the effects of different percentages of canola oil and fish oil containing n-3 highly unsaturated fatty acids
(n-3 HUFA) on fish growth and fatty acid composition. The requirement for n-3 HUFA of juvenile Iranian sturgeon (48.4 ± 1.98 g)
was studied by feeding the fish with various diets containing six different percentage of n-3 HUFA ranging from 1.56 to 17.25
(% of total fatty acids). Neither the weight gain, feed conversion ratio, condition factor, specific growth rate nor the protein
efficiency ratio showed any significant differences between the dietary treatments nor in the body composition of juvenile
Iranian sturgeon (P > 0.05); also there were no significant difference with respect to the effect of the dietary treatment (P > 0.05) on the blood parameters, for the content of plasma protein, glucose, cholesterol, and triglyceride. The fatty acid
composition of the carcass of the Iranian sturgeon fed with the diets containing various levels of n-3 HUFA was reflected
by the dietary fatty acid composition. The content of n-3 HUFA in the fish increased with an increase in dietary n-3 HUFA
levels. The results indicate that the dietary n-3 HUFA had no effect on the growth of juvenile Iranian sturgeon. 相似文献
109.
Ullah Sami Assiri Mohammed Ali Bustam Mohamad Azmi Al-Sehemi Abdullah G. Abdul Kareem Firas A. Irfan Ahmad 《Paddy and Water Environment》2020,18(2):455-468
Paddy and Water Environment - The use of low-cost adsorbents produced from rice husks that can selectively remove zinc (II) ion from wastewater effluent has been investigated. The disorder and... 相似文献
110.
Alkhadher Sadeq A. A. Kadir Aeslina Abdul Zakaria Mohamad Pauzi Adel Al-Gheethi Magam Sami M. S. Masood Najat 《Journal of Soils and Sediments》2020,20(8):3230-3242
Journal of Soils and Sediments - Molecular organic markers are an effective tool to detect the adverse effects of anthropogenic inputs in the aquatic environment. Linear alkylbenzenes (LABs) are... 相似文献