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Muhammad Naveed Yousaf Erling Olaf Koppang Karsten Skjødt Ivar Hordvik Jun Zou Chris Secombes Mark D. Powell 《Veterinary immunology and immunopathology》2013,151(1-2):49-62
The heart is considered the powerhouse of the cardiovascular system. Heart and skeletal muscle inflammation (HSMI), cardiomyopathy syndrome (CMS) and pancreas disease (PD) are cardiac diseases of marine farmed Atlantic salmon (Salmo salar) which commonly affect the heart in addition to the skeletal muscle, liver and pancreas. The main findings of these diseases are necrosis and inflammatory cells infiltrates affecting different regions of the heart. In order to better characterize the cardiac pathology, study of the inflammatory cell characteristics and cell cycle protein expression was undertaken by immunohistochemistry. Immunohistochemistry was performed on paraffin embedded hearts from confirmed diseased cases applying specific antibodies. The inflammatory cells were predominantly CD3+ T lymphocytes. The PD diseased hearts exhibited moderate hypoxia inducible factor-1α (HIF1α) immuno-reaction that suggested tissue hypoxia while recombinant tumor necrosis factor-α (rTNFα) antibody identified putative macrophages and eosinophilic granulocytes (EGCs) in addition to endocardial cells around lesions. There were strong to low levels of major histocompatibility complex (MHC) class II immunostaining in the diseased hearts associated with macrophage-like and lymphocyte-like cells. The diseased hearts expressed strong to low levels of apoptotic cells identified by caspase 3 and terminal deoxynucleotidyl transferase nick-end labeling (TUNEL) staining. The strong signals for proliferative cell nuclear antigen (PCNA) and TUNEL, and moderate levels of caspase 3 immuno-reactivity suggested a high cell turnover where DNA damage/repair might be occurring in the diseased hearts. Interestingly, the apparently similar cardiac diseases exhibited differences in the immunopathological responses in Atlantic salmon. 相似文献
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Jon Olaf Olaussen Yajie Liu 《Aquaculture Economics & Management (Blackwell Science)》2013,17(4):245-261
This article explores to what extent escaped farmed salmon from fish farms affect the willingness-to-pay for recreational fishing of Atlantic salmon in Norwegian rivers. This is a first attempt to explore the economic consequences of escaped farmed species in terms of the anglers’ willingness-to-pay for fishing permits working through the relationship between the price of fishing permits and the share of escaped farmed salmon. The empirical analysis is based on the results from a contingent valuation survey conducted in Norway. It is found that the presence of escaped farmed salmon in Norwegian rivers may have severe economic consequences on the willingness-to-pay for recreational fishing with a reduction of up to 85% compared to a situation with a ‘pure’ wild salmon stock. 相似文献
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Lisa Scott Paula Menzies Richard J. Reid-Smith Brent P. Avery Scott A. McEwen Catherine S. Moon Olaf Berke 《Canadian journal of veterinary research》2012,76(2):109-119
The purpose of this study was to examine the prevalence and patterns of antimicrobial resistance (AMR) in enteric bacteria obtained from Ontario sheep flocks, and associations between antimicrobial use (AMU) and AMR. Forty-nine sheep producers participated for a 1-year interval between 2006 and 2008. Two-hundred and eighty-three pooled fecal samples were collected from the flocks during initial and final visits. Up to 3 isolates of Salmonella spp. and generic E. coli per pooled fecal sample were tested for susceptibility to 15 antimicrobials. Resistance was infrequent among Salmonella (0%, n = 7 isolates) and low among E. coli (13.1%; n = 849) isolates. A small number of isolates were resistant to antimicrobials classified as being of very high importance to human health. Tetracycline resistance was most frequently observed (12.0%). Logistic regression was used to model potential AMU (qualitative and quantitative) risk factors for tetracycline resistance in generic E. coli from final visits. Qualitative analysis indicated that the use of injectable sulfonamides [including trimethoprim-sulfonamide combinations (TMS)] and tetracycline in the feed and water were significantly associated with tetracycline resistance (OR = 2.6, P = 0.01; and OR = 4.8, P ≤ 0.01, respectively). Quantitative analysis also indicated that TMS exposure rate was significantly associated with tetracycline resistance, which varied depending on the exposure rate. The exposure rate of tetracycline in the feed and water was only significant after the removal of one influential flock, warranting further research examining flocks with higher tetracycline exposure rates. Although the prevalence of AMR in participating flocks was relatively low, risk factors for resistance were identified. 相似文献
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Journal of Soils and Sediments - This study assessed the efficacy of selected silicon-rich soil amendments in terms of their ability to provide dissolved silicon (Si) to soil solutions during a... 相似文献