Undernutrition in the parental and first generation provokes an organ‐specific response to oxidative stress on neonates of second filial generation of Wistar rats          下载免费PDF全文

R. Baños‐Gómez  N. S. Cruz‐Cansino  T. Suarez‐Diéguez  C. Valadez‐Vega  E. Ramírez‐Moreno  E. Alanís‐García  J. A. Ariza‐Ortega  J. J. Manríquez‐Torres  E. Zamora‐Romo  L. Delgado‐Olivares 《Journal of animal physiology and animal nutrition》2017,101(2):267-274

Undernutrition induces an increase of the oxidative stress that can predispose offspring to various diseases in adulthood through epigenetic reprogramming. The aim of this study was to evaluate the effects of intergenerational undernutrition on protein oxidation and antioxidant defence response on liver, heart and brain of the second‐generation neonates (F₂) of undernourished rats. For this purpose, both parents in parental (F₀) and first generation (F₁) were fed with a low‐nutrient diet. Body mass and length decreased (p < 0.05) in F₀, F₁ and F₂ being the F₁ males who exhibited a greater mass loss. A decrease in plasma albumin concentration was observed in F₂ neonates (p < 0.05) and also a mass loss of liver, heart and brain (p < 0.05), although proportionally to body length reduction. Undernutrition increased levels of protein oxidation in liver and heart (p < 0.05) but not in brain (p > 0.05) while catalase activity increased only in brain (p < 0.05). In summary, intergenerational undernutrition modifies the antioxidant status through an organ‐specific response, on F₂ neonate rats, where the brain increased catalase activity to prevent a severe oxidative damage and support the vital functions of this key organ to maintain vital functions.  相似文献   

Melanin granules melanophages and a fully‐melanized epidermis are common traits of odontocete and mysticete cetaceans          下载免费PDF全文

Blanca Morales‐Guerrero  Cecilia Barragán‐Vargas  German R. Silva‐Rosales  Christian D. Ortega‐Ortiz  Diane Gendron  Laura M. Martinez‐Levasseur  Karina Acevedo‐Whitehouse 《Veterinary dermatology》2017,28(2):213-e50

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The Odd Log-Logistic Student <Emphasis Type="Italic">t</Emphasis> Distribution: Theory and Applications     

Altemir da Silva Braga  Gauss M. Cordeiro  Edwin M. M. Ortega  Giovana O. Silva 《Journal of Agricultural, Biological & Environmental Statistics》2017,22(4):615-639

The normal distribution is most used in analysis of experiments. However, it is not suitable to apply in situations where the data have evidence of bimodality or heavier tails than the normal distribution. So, we propose a new four-parameter model called the odd log-logistic Student t distribution as an alternative to the normal and Student t distributions. The new distribution can be symmetric, platykurtic, mesokurtic or leptokurtic and may be unimodal or bimodal. Its various structural properties can be determined from the linear representation of its density function. The estimation of the model parameters is performed by maximum likelihood. The proposed distribution can be used as an alternative for randomized complete block design, thus providing analysis of real data more realistic than other special regression models. We perform a sensitivity analysis to detect influential or outlying observations, and construct generated envelopes from the residuals to select appropriate models. We illustrate the importance of the proposed model by means of three real data sets in analysis of experiments carried out in different regions of Brazil.  相似文献   

Humic acid adsorption and its role in colloidal‐scale aggregation determined with the zeta potential,surface free energy and the extended‐DLVO theory          下载免费PDF全文

J. Calero  A. Ontiveros‐Ortega  V. Aranda  I. Plaza 《European Journal of Soil Science》2017,68(4):491-503

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Effects of Chloroformic Extracts from Washed and Unwashed Papaya Seeds (Carica papaya) on the Sperm Concentration of Dogs     

A Ortega‐Pacheco  M Jiménez‐Coello  E Gutiérrez‐Blanco  KY Acosta‐Viana  E Guzmán‐Marín  MA Zavala‐Sánchez  NE Montalvo‐Beltrán  MS Pérez‐Gutiérrez 《Reproduction in domestic animals》2010,45(6):1126-1129

Papaya seeds (Carica papaya Linn) have been found to have a significant effect on sperm characteristics in some mammals, including humans, but no studies have investigated the effects on dogs. In the present study, a significant decrease in sperm concentration was observed in a group of dogs treated with extracts from washed papaya seeds, but no decrease was observed in the group of dogs treated with non‐washed seeds. An important effect of extract components from washed seeds such as fatty acids is probably involved in the reduction of sperm production because of Sertoli cell damage, as has been suggested for langur monkeys. Dilution of the active components in the non‐washed papaya seeds or interference with some of the components may reduce the expected effect on spermatogenesis. This first report on the effects of a chloroformic extract of papaya seeds in dogs suggests that an increased dose is necessary to achieve azoospermia.  相似文献   

The effect of a single intramammary infusion of a biological response modifier in cows at drying off     

Bibiana Elisabet Dallard  H. H. Ortega  I. A. Iguzquiza  N. R. Salvetti  O. A. Quaino  L. F. Calvinho 《Veterinary research communications》2010,34(6):519-532

Biological response modifiers (BRM) are compounds that interact with the immune system to regulate specific aspects of host response. The objective of this study was to describe clinical and morphological changes during involution of bovine mammary gland following a single-dose infusion of a BRM containing lipopolysaccharide and cellular fractions of Escherichia coli incorporated into liposomes. A massive leukocyte response and increased subepithelial stroma infiltration of mononuclear cells, eosinophils and mast cells was observed in BRM-treated quarters compared with untreated controls; however, morphologic parameters assessed at 11 days post infusion were indicative of only slightly accelerated involution compared with untreated controls. In addition, BRM infusion at the end of lactation did not interfere with mammary epithelial cell proliferation and caused only mild systemic effects.  相似文献   

Germplasm enhancement with wild tuber-bearing species: introgression of PVY resistance and high dry matter content fromSolanum berthaultii, S. gourlayi, S. tarijense andS. vernei     

Felisa Ortega  Ana Carrasco 《Potato Research》2005,48(1-2):97-104

Summary The narrow genetic base of the cultivated potato is a severe constraint for potato breeding. Wild tuber-bearing species constitute an important source of genes for resistance to diseases and pests as well as abiotic factors. Seven interspecific hybrid populations were generated from crosses between diploidTuberosum clones and four wild species:Solanum berthaultii, S. gourlayi, S. tarijense andS. vernei, and evaluated in a field experiment in Burgos (Spain) as a way to broaden the genetic base of the cultivated potato. Good tuberization ability and great variability for yield within the different families were detected. Hybridization with the wild species resulted in high levels of PVY resistance inS. berthaultii andS. vernei hybrids and a large increase of dry matter content in all populations except theS. berthaultii hybrids.  相似文献   

Late Pleistocene ‐ Holocene palaeosols in the north of Sonora,Mexico: chronostratigraphy,pedogenesis and implications for environmental history     

T. Cruz‐y‐Cruz  S. Sedov  G. Sánchez  T. Pi‐Puig  K. Pustovoytov  H. Barceinas‐Cruz  B. Ortega‐Guerrero  E. Solleiro‐Rebolledo 《European Journal of Soil Science》2014,65(4):455-469

Red palaeosols of the late Pleistocene‐early Holocene, both buried and non‐buried, were studied recently in Sonora (NW Mexico) to reconstruct their pedogenesis as well as the palaeoenvironmental conditions. The alluvial palaeosol‐sedimentary sequence of the La Playa archaeological site is a key locality for the buried San Rafael palaeosol, which exhibits a 2Ah‐2Bw‐2BCk‐3Bgk profile and was defined as a Chromic Cambisol. Radiocarbon dates from pedogenic carbonates and charcoal set the soil formation interval between > 18 000 and 4300 calibrated years before present (cal. year BP). Micro‐morphological observations together with profile distribution of clay, carbonates, organic carbon, pedogenic iron oxides and rock magnetic properties indicated a strong eluvial‐illuvial redistribution of carbonates, moderate silicate weathering and gleying in the lower horizon. Although this soil was much more developed than the overlying syn‐sedimentary late Holocene Fluvisols, clay mineral composition and stable carbon isotope signatures of humus and carbonates were similar in both soils. We suggest that pedogenesis of the San Rafael palaeosol took place under a slightly more humid climate and relative geomorphic stability. This agrees with the regional palaeoclimate reconstruction, which indicates a moister climate during the Late Wisconsin glaciation (MIS 2). An abrupt termination of the San Rafael pedogenesis marked by disturbance and aridization features in the Ap horizon of the palaeosol could be linked to a global drought around 4200 years cal. year BP. Surface Chromic Cambisols in northern Sonora show similar pedogenetic characteristics to the buried red palaeosols of La Playa. They appear to be a relict component of the present day soil mantle.  相似文献   

Proinflammatory cytokines and CD14 expression in mammary tissue of cows following intramammary inoculation of Panax ginseng at drying off     

Baravalle C  Dallard BE  Cadoche MC  Pereyra EA  Neder VE  Ortega HH  Calvinho LF 《Veterinary immunology and immunopathology》2011,144(1-2):52-60

The lack of efficacy of conventional strategies for the maintenance of healthy udders in domestic cattle has prompted studies on the use of immunomodulators or biological response modifiers (BRM) for this purpose. These compounds are agents that modify the host's response to pathogens leading to beneficial effects on disease outcome. The objective of this study was to evaluate the effects of a single intramammary infusion of Panax ginseng (GS) extract on the amount of pro-inflammatory cytokines and the number of monocytes/macrophages present in bovine mammary tissues at drying off. Eight mammary quarters from six nonpregnant cows in late lactation were infused with 10 mL of GS (3mg/mL), six quarters were treated with 10 mL of placebo (vehicle alone) and six quarters were maintained as uninoculated controls. The analyses of tumor necrosis factor-alpha (TNF-α) by immunohistochemistry revealed that the production of this proinflammatory cytokine significantly increased (P<0.05) in the inoculated mammary glands of cows following BRM inoculation, whereas the interleukin-1 alpha (IL-1α) and IL-6 staining area was not affected by BRM treatment. The number of monocytes/macrophages detected with CD14 antibody was significantly higher (P<0.05) in BRM-treated quarters than in placebo and uninoculated control quarters. These results indicated an immunomodulator potential of the BRM used. The beneficial effect of the extract could be used as alternative therapy in the control of mastitis at drying off, either alone or in conjunction with dry cow antibiotic therapy.  相似文献   

Mycoparasitic Trichoderma isolates as a biocontrol agent against Valsa ceratosperma,the causal agent of apple valsa canker     

Valetti  Lucio  Lima  Nelson Bernardi  Cazón  Luis I.  Crociara  Clara  Ortega  Leandro  Pastor  Silvina 《European journal of plant pathology / European Foundation for Plant Pathology》2022,163(4):923-935

European Journal of Plant Pathology - Apple valsa canker, caused by the fungus Valsa ceratosperma, is one of the most destructive diseases of this crop. Conventional fungicide treatments are not...  相似文献