Immunological and feeding studies on antigens derived from the biting fly, Stomoxys calcitrans.     

K A Webster  M Rankin  N Goddard  D W Tarry  G C Coles 《Veterinary parasitology》1992,44(1-2):143-150

Pairs of rabbits were immunised with three antigenic preparations derived from Stomoxys calcitrans gut, abdominal section and whole flies. Immunoblotting studies demonstrated that a humoral response was mounted against eight antigens from the gut preparation and 12 each from the abdominal and whole fly preparations. In vitro feeding experiments showed higher mortality between Days 4 and 7 in the group of flies which had fed upon blood from rabbits inoculated with the gut derived antigen. This group also produced the lowest percentage of viable eggs (15.5%).  相似文献   

A survey of Western Australian dogs for Sarcocystis spp and other intestinal parasites     

G SA VINI  JD DUNSMORE  ID ROBERTSON 《Australian veterinary journal》1993,70(7):275-276

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Comparison of the pharmacokinetics and thermal antinociceptive pharmacodynamics of 20 µg kg⁻¹ buprenorphine administered sublingually or intravenously in cats     

BDX  Lascelles †  SA Robertson ‡  PM Taylor§  J Hauptman¶ 《Veterinary anaesthesia and analgesia》2003,30(2):108-108

Little is known about the analgesic action of buprenorphine (BUP) in cats. Relative to man, the cat has a more alkaline oral pH, which may make this an effective route for administering BUP in this species. This study aimed to assess and compare the pharmacokinetics and pharmacodynamics of sublingual (S‐L) and IV administration of BUP. Thermal threshold (TT) was measured and blood samples were collected following IV or S‐L administration (20 µg kg^?1) of the injectable formulation. Six cats (five spayed females, one castrated male, 4.1–6.6 kg) were used. Each cat received both treatments in a randomized cross‐over study design with 1 month between experiments. Twenty‐four hours prior to each study, the lateral thorax of each of the cats was shaved, cephalic and jugular catheters placed, and oral pH measured. On the day of the study, TT was measured using a ‘thorax‐mounted’ thermal threshold‐testing device specifically developed for cats. The cats were free to move around. Skin temperature was recorded before each test, then the heater activated. When the cat responded by flinching, turning, or jumping, the stimulus was terminated and the threshold temperature was recorded. The thermal threshold cut‐off point was 55.5 °C. Three baseline thresholds were recorded before treatment with S‐L or IV (via cephalic catheter) BUP (20 µg kg^?1). Blood was withdrawn (jugular) at 1, 2, 4, 6, 10, 15, 30, 45, 60 minutes and at 2, 4, 6, 8, 12, and 24 hours post‐administration. TT was measured every 30 minutes?6 hours, 1–12 hours, and at 24 hours post‐administration. Plasma was immediately separated, stored at ?20.5 °C, and assayed within 4 months using a commercially available ¹²⁵I radioimmunoassay. Threshold data were analyzed using anova with a repeat factor of time. No adverse effects were noted. Pupils were dilated for up to 9 hours post‐BUP. Behavioral changes were calm euphoria. Measured oral pH was 9 in each cat. Pre‐treatment mean threshold (±SD) was 41.2 ± 0.9 °C in the S‐L group and 40.8 ± 0.85 °C in the IV group. There were no significant differences between the groups with respect to thresholds over time (p = 0.72). Thresholds were significantly increased from 30 to 360 minutes in both the groups (>44.615 °C). Peak plasma BUP (C_max) was lower (11 ± 6.7 ng mL^?1vs. 92.9 ± 107.9 ng mL^?1) and occurred later (T_max) (30 minutes vs. 1 minute) after S‐L compared to IV administration, respectively. BUP (20 µg kg^?1)‐administered S‐L or IV provided antinociception between 30 and 360 minutes after administration. Plasma levels did not correspond to TT.  相似文献   

Pilot study to quantify the time to clear dexamethasone from plasma and urine of adult horses following a single nebulisation     

NE Symonds  AJ Dart  J Keledjian  M Liu Lau  LC Ennis  VC McIver  AS Tsang  SA Biasutti  LB Jeffcott 《Australian veterinary journal》2019,97(5):144-148

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Severe soft tissue infections in dogs: 47 cases (1996–2006)     

Yekaterina Buriko  Thomas J. Van Winkle  Kenneth J. Drobatz  Shelley C. Rankin  Rebecca S. Syring 《Journal of Veterinary Emergency and Critical Care》2008,18(6):608-618

Objective– To describe the patient population, microbiological findings, treatment and outcome in dogs with severe soft tissue infections (SSTIs) and to compare survivors to nonsurvivors. Design– Retrospective study. Animals– Forty‐seven dogs with confirmed soft tissue infections originating from the SC tissues, muscle or fascia. Interventions– None. Measurements and Main Results– Physical and clinicopathologic data on presentation, microbiological and histopathological findings, antimicrobial treatment and outcome. Dogs with SSTIs were predominantly large breed dogs with a median body weight of 35.6 kg. Incidence of pre‐existing conditions (immunomodulating diseases, blunt trauma, injections, clean surgical procedures) that could have contributed to development of SSTIs was 34%. Abnormal physical examination and diagnostic parameters on presentation included increased body temperature (median temperature 39.5 °C [103.1 °F]) and low arterial blood pressure (median systolic blood pressure 103.5 mm Hg). While Streptococcus species were the most commonly isolated bacteria, the incidence of polymicrobial infections differed between antemortem (38.7%) and postmortem (57.1%) cultures. The overall survival rate was 46.8%. Survivors had a higher body weight and higher respiratory rate on presentation than nonsurvivors. Nonsurvivors had a significantly lower WBC count and higher lactate, BUN, aspartate aminotransferase, and bilirubin concentrations. Histopathologic examination of tissue specimens showed that the degree of necrosis was higher in survivors compared with nonsurvivors. Conclusions– SSTIs in dogs are serious conditions associated with high mortality, significant inflammatory changes, and cardiovascular compromise. A number of conditions, including those that compromise skin integrity and immunomodulating diseases have been identified in our patient population and could have contributed to development of SSTIs. Polymicrobial infections occurred in many cases, necessitating broad‐spectrum antimicrobial coverage.  相似文献   

Measurement of plasma gentamicin concentrations postchemical ciliary body ablation in dogs with chronic glaucoma          下载免费PDF全文

Amy J. Rankin  Rick Lanuza  Butch KuKanich  William C. Crumley  Jonathan D. Pucket  Rachel A. Allbaugh  Jessica M. Meekins 《Veterinary ophthalmology》2016,19(1):57-62

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Comparative efficacy of BioRelease Deslorelin® injection for induction of ovulation in oestrus mares: a field study          下载免费PDF全文

SA Finan  EL Lamkin  AO McKinnon 《Australian veterinary journal》2016,94(9):338-340

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Dachshund bitch with severe uterine adhesions and intramural uterine foreign material as an incidental ovariohysterectomy finding          下载免费PDF全文

KM Watson  NU Horadagoda  SA Piripi 《Australian veterinary journal》2016,94(1-2):24-26

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Seroprevalence of Toxoplasma gondii in mainland and sub-Antarctic New Zealand sea lion (Phocarctos hookeri) populations     

SA Michael  L Howe  BL Chilvers  PCH Morel  WD Roe 《New Zealand veterinary journal》2016,64(5):293-297

AIMS: To investigate the seroprevalence of antibodies to Toxoplasma gondii in New Zealand sea lions (Phocarctos hookeri), as a potential contributor to reproductive failure.

METHODS: Archived sera were sourced from New Zealand sea lions from two recolonising mainland populations in the Otago Peninsula (n=15) and Stewart Island (n=12), as well as a declining population at Enderby Island (n=28) in the New Zealand sub-Antarctic. Sera were tested for antibodies to T. gondii using a commercially available ELISA (with samples considered positive if the sample to positive ratio was?>30%), and latex agglutination test (LAT; with titres ≥1:32 considered positive). Western blot analysis was used to validate the results of a subset of 14 samples.

RESULTS: Five samples from sea lions in mainland locations were confirmed positive for antibodies to T. gondii. Two adult females exhibited high LAT antibody titres (min 1:2048, max 1:4096) on both occasions when sampled 1 and 2 years apart, respectively. No animals from Enderby Island were seropositive.

CONCLUSIONS: Toxoplasma gondii infection is unlikely to be a major contributor to poor reproductive success in New Zealand sea lions. However, continued surveillance is pertinent to assess subclinical and clinical impacts of the parasite on these threatened populations. The commercial tests evaluated here, with further species-specific threshold refinement could provide a fast, inexpensive and reliable indicator of T. gondii exposure in New Zealand sea lions.  相似文献   

Laparoscopic ovariectomy in eastern grey kangaroos (Macropus giganteus) and red kangaroos (Macropus rufus)          下载免费PDF全文

SA Colgan  LA Green 《Australian veterinary journal》2018,96(3):86-92

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