Primary mesenteric root osteosarcoma in a dog     

Rebeccah Urbiztondo  Seth Chapman  Kevin Benjamino 《Veterinary clinical pathology / American Society for Veterinary Clinical Pathology》2010,39(3):377-380

Abstract: A 10‐year‐old spayed female Boxer‐mix was presented with a history of several weeks of soft stools, straining to defecate, inappetance, and lethargy and several days of hematochezia, melena, and dyschezia. Physical examination findings included mild tachycardia and tense cranial abdomen. CBC results indicated moderate mature neutrophilia. Ultrasonographic examination of the abdomen revealed a large mass with complex echogenicity in the cranial abdomen, likely associated with the intestines. Cytologic examination of a fine‐needle aspirate revealed a population of round, stellate, and spindle‐shaped cells arranged individually and in aggregates with occasional cells embedded in an eosinophilic extracellular matrix. The cytologic interpretation was malignant mesenchymal neoplasm with osteosarcoma being the primary differential. Surgical exploration of the abdomen revealed a 10‐cm‐diameter mass located at the intestinal mesenteric root. The mass occluded blood flow to portions of the gastrointestinal tract. The dog was euthanized due to the nonresectable nature of the tumor. Histopathologic examination revealed an expansile poorly demarcated mesenchymal neoplasm composed predominantly of spindloid and pyriform cells, occasionally embedded in a matrix compatible with osteoid. The diagnosis was extraskeletal osteosarcoma of the intestinal mesenteric root, only rarely reported in dogs.  相似文献   

MENSURATION OF THE PITUITARY GLAND FROM MAGNETIC RESONANCE IMAGES IN 17 CATS     

Seth T.  Wallack  DVM  Erik R.  Wisner  DVM  Edward C.  Feldman  DVM 《Veterinary radiology & ultrasound》2003,44(3):278-282

The objective of this retrospective study was to estimate using magnetic resonance imaging the size range of the pituitary gland in cats who had no evidence of pituitary disease. The pituitary gland was measured from transverse and sagittal magnetic resonance postgadolinium T1-weighted images in 17 cats. The cats were 0.83 to 15 years of age and weighed between 2.9 and 6.5 kg. Linear pituitary measurements were performed on a dedicated workstation using electronic calipers. Mean (+/- standard deviation) pituitary gland length was 0.54 cm (+/- 0.06 cm) and mean width was 0.50 cm (+/- 0.08 cm). Mean pituitary gland height measured on sagittal images was 0.34 cm (+/- 0.05) and measured on transverse images was 0.32 cm (+/- 0.04 cm). Mean pituitary volume was 0.05 cm3 (+/- 0.01 cm3). There was no significant correlation between cat weight (kg) and pituitary volume or age and pituitary volume. The pituitary gland appearance varied on pre- and postcontrast T1-weighted images. On the precontrast images, the majority of pituitary glands had a mixed signal intensity. On postcontrast images, uniform pituitary gland enhancement was seen commonly.  相似文献   

Thyroid follicular adenocarcinoma in a ferret     

Wills TB  Bohn AA  Finch NP  Harris SP  Caplazi P 《Veterinary clinical pathology / American Society for Veterinary Clinical Pathology》2005,34(4):405-408

A 5-year-old male castrated ferret was presented to the Washington State University College of Veterinary Medicine for evaluation of progressive hair loss and a large, rapidly growing ventral neck mass. The patient had been diagnosed previously with an insulinoma, which was managed medically. Fine-needle aspirates of the neck mass were performed. The cytologic results were most consistent with epithelial neoplasia, likely a carcinoma; thyroid origin was considered likely based on tumor location and cell morphology. The tumor grew rapidly, and the owners elected euthanasia 1 week after examination. At necropsy, a circumscribed, ovoid mass disrupted the right cervical musculature next to the right lobe of the thyroid gland. Histopathologic evaluation revealed an infiltrative mass consisting of cuboidal cells arranged in solid sheets and irregular follicles enclosing colloid. The cells were large, with prominent nucleoli, and had a high mitotic rate. The histopathologic diagnosis was consistent with thyroid follicular adenocarcinoma. Immunochemical findings confirmed thyroglobulin production by neoplastic cells, but to a lesser extent than in normal ferret thyroid tissue. To our knowledge, this is the first case of thyroid follicular adenocarcinoma to be reported in a ferret, with only 1 other case of thyroid carcinoma, a C-cell carcinoma, described previously.  相似文献   

US agriculture is vulnerable to bioterrorism     

Moon HW  Kirk-Baer C  Ascher M  Cook RJ  Franz DR  Hoy M  Husnik DF  Jensen HH  Keller KH  Lederberg J  Madden LV  Powers LS  Steinberg AD  Strating A  Smith RE  Kuzma J  Grossblatt N  Holliday L  Sweatt D  Strongin S 《Journal of veterinary medical education》2003,30(2):96-104

  相似文献   

RADIOLOGICAL ASSESSMENT OF THE RELATIONSHIP BETWEEN THORACIC CONFORMATION AND THE RISK OF GASTRIC DILATATION-VOLVULUS IN DOGS     

Larry  Glickman  VMD  DrPH  Tim  Emerick  BS  Nita  Glickman  MS  MPH  Seth  Glickman  Gary  Lantz  DVM  Cynthia  Pérez  PhD  Diana  Schellenberg  MS  William  Widmer  DVM  MS  Qi-long  Yi  PhD 《Veterinary radiology & ultrasound》1996,37(3):174-180

To test the hypothesis that breeds of dogs with a deeper and narrower thorax have an increased risk of gastric dilatation-volvulus (GDV), thoracie depth, width, and length were measured for 437 dogs of 17 different breeds using radiographs on file at the Veterinary Teaching Hospital of the Purdue University School of Veterinary Medicine for the period of 1977 to 1993. These data were applied to risk estimates of GDV that were generated from a separate case control study using the Veterinary Medical Data Base. Multiple linear regression analysis was used to relate the mean thoracie measurements and the ideal, adult body size of the breeds to the risk of each breed developing GDV. When the risk of GDV was evaluated as a function of the mean thoracie depth/width ratio alone, or as a function of the thoracie depth/width ratio plus ideal adult breed weight, 37% (p = 0.022), respectively, of the variability in GDV risk was explained. These findings support the hypothesis tested and suggest that selective breeding can be used to decrease a breed's risk of GDV over time.  相似文献   

Structural basis of transcription initiation: an RNA polymerase holoenzyme-DNA complex     

Murakami KS  Masuda S  Campbell EA  Muzzin O  Darst SA 《Science (New York, N.Y.)》2002,296(5571):1285-1290

  相似文献   

Phosphorus pools in soil after land conversion from silvopasture to arable and grassland use          下载免费PDF全文

Anna Slazak  Dirk Freese  Eduardo S. Matos  Seth Nii‐Annang  Reinhard F. Hüttl 《植物养料与土壤学杂志》2014,177(2):159-167

Differences in soil P among silvopasture, grassland, and arable lands have been well established. Nevertheless, most of the reports compare soil properties under long‐term sites. Thus, there exists little information on the effect of the conversion of silvopasture to arable or grassland use on soil P pools. The objective of the study was to determine the impact of converting silvopasture system (SP) into arable cropping and grassland system on the distribution of P pools and potential P bioavailability. We compared the following systems: SP system, SP converted to arable cropland (SP‐AL), SP converted to grassland (SP‐GL), and for comparative purposes, a long‐term arable cropland (AL). The P fractionation was performed by a sequential extraction scheme, using acid and alkaline extractants on samples collected from the 0–10 and 10–20 cm soil layers. It was assumed that the large variations in soil‐P fractionations are caused by the different management practices associated with land conversion. The results of P fractionation showed a dominance of calcium‐bound P, HCl‐extractable Pi constituted up to 36% of the soil total P (TP). However, the type of land use did not affect this P fraction. On the other hand, the reduction in labile‐P_i and NaOH‐P_i fractions observed at the SP‐AL site may have led to the decline in readily available P. The soil total organic P (TP_o) content was 8% and 17% lower at SP‐AL compared to SP and SP‐GL site, respectively. Labile organic‐P (labile‐P_o) content was markedly higher at SP site compared to arable soils, and was ≈ 10% of TP_o. The NaOH‐P_o constituted the highest fraction of the organic‐P pool (55%–79% of TP_o) across all the study systems, and was positively correlated with TP_o (p < 0.01). The study indicates that conversion of SP system in temperate regions to arable cropping with conventional tillage seems to result in the reduction of P availability compared to SP, indicating SP as an important land‐use practice.  相似文献   

Structural basis of transcription initiation: RNA polymerase holoenzyme at 4 A resolution     

Murakami KS  Masuda S  Darst SA 《Science (New York, N.Y.)》2002,296(5571):1280-1284

  相似文献   

美国西部重要害虫摩门螽斯病原真菌的研究     

唐诺德·罗伯茨 《安徽农业大学学报》2007,34(2):141-148

The Mormon cricket (MC),Anabrus simplex (Orthoptera:Tettigoniidae),has a long and negative history with agriculture in the western states of the USA where MC often migrates in large groups and causes significant damage to forage plants and cultivated crops.In this review, virulence to MC of isolates of the insect-pathogenic fungus Metarhizium anisopliae varieties acridum and anisopliae were compared in an effort to identify isolates with promise for use as MC biological control agents.All of the isolates tested induced 100% or nearly 100% mortality by six days post application of the fungal conidia.Searches for new Metarhizium isolates with high heat and UV-B tolerance included isolation fungi from field-caught MC and grasshopper after they died in the laboratory and culturing fungi from soil samples collected from numerous western USA sites.The survey was preceded by development of a dodine based selective medium that,at 0.002% active ingredient,permitted growth of M.anisopliae var.acridum,but inhibited most contaminating fungi.The M.anisopliae var.acridum isolates examined to date have much higher tolerance to heat and UV-B irradiation than M.anisopliae var.anisopliae isolates,and this may be critical to successful field applications.The variety acridum has not yet been found in the USA,so our search for such isolates continues.Several new M.anisopliae var.anisopliae and Beauveria spp.were found,and the Metarhizium isolates are being characterized as to stress tolerance and virulence to insects.Characterization includes comparisons of new and pre-existing Metarhizium isolates by amplified fragment-length polymorphism (AFLP) analysis.Finally, experiments on MC developmental biology were conducted to gather data needed to develop a degree day model and to establish laboratory colonies of MC.  相似文献   

Auxin and kinetin interaction in apical dominance     

Davies CR  Seth AK  Wareing PF 《Science (New York, N.Y.)》1966,151(3709):468-469

The effects of auxin on the inhibition of lateral buds in decapitated bean plants are enhanced if kinetin is applied together with auxin. The uptake of (14)C-indoleacetic acid by the stumps of decapitated plants is increased in the presence of kinetin and leads to extensive transport of (14)C-indoleacetic acid in the stems. The increased bud inhibition resulting when auxin and kinetin are applied together may be due to greater amounts of auxin reaching the buds, but an alternative explanation is that metabolites are directed from the buds to the point of hormone application.  相似文献