Paul e. Nelson, 1927 to 1996     

Tammen JF  Toussoun TA  Horst RK  Burgess LW  Marasas WF 《Phytopathology》1999,89(12):1126

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Spatial and stochastic simulation to evaluate the impact of events and control measures on the 1997-1998 classical swine fever epidemic in The Netherlands. II. Comparison of control strategies     

Nielen M  Jalvingh AW  Meuwissen MP  Horst SH  Dijkhuizen AA 《Preventive veterinary medicine》1999,42(3-4):297-317

Using the spatial, temporal and stochastic simulation model InterCSF, several alternative pre-emptive slaughter strategies that could have been applied in the Dutch Classical Swine Fever (CSF) epidemic of 1997–1998 were evaluated. Furthermore, effects of changes in some disease-spread and disease-control parameters were studied. InterCSF simulates the spread of CSF between farms through local spread and contacts (animals, transport and persons). Disease spread is affected by control measures implemented through different mechanisms (e.g. depopulation of infected farms, pre-emptive slaughter, movement control). The starting point for the evaluation of strategies was a simulated basic scenario, which mimicked the real epidemic. Strategies were compared using epidemiological as well as economic results. Economic results were generated by a separate model (EpiLoss) that calculated the direct losses and consequential losses for farmers and related industries. The comparison of the different alternatives to the basic scenario led to some general conclusions on the Dutch CSF-epidemic. Pre-emptive slaughter seemed to be an effective strategy to reduce the size of an epidemic, if started at an early stage. Economically, pre-emptive slaughter was not as expensive as expected; the resulting smaller size of the epidemic, combined with less welfare slaughter, led to much lower overall losses. Furthermore, although large movement control areas seemed effective in reducing the size of the epidemic, the total losses were relatively high because of subsequent welfare slaughter. If infection probabilities could be reduced, for example by improved biosecurity, the resulting epidemics would be much smaller.  相似文献   

Dr. James E. Kraus     

Walter Sparks 《American Journal of Potato Research》1972,49(9):352-353

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SURFACE-INDUCED DEEP HYPOTHERMIA – A PRACTICAL METHOD FOR CARDIAC ARREST SURGERY IN THE DOG     

Walter E. Weirich D.V.M.  M.S.  Ph.D. 《Veterinary surgery : VS》1974,3(2):82-87

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Effect of Variable Temperature on Infection Severity of Podosphaera macularis on Hops     

Mahaffee WF  Turechek WW  Ocamb CM 《Phytopathology》2003,93(12):1587-1592

ABSTRACT The effect of variable temperature on the infection severity of Podosphaera macularis was investigated. Potted 'Symphony' hop plants were inoculated and exposed to different temperature regimes that included supraconducive temperatures (30 to 42 degrees C) for varying periods of time (2 to 9 h). Infection severity (lesions per cm(2) of leaf area) was calculated 7 to 10 days after inoculation. Immediately exposing inoculated plants to 30 degrees C for as little as 2 h significantly (P 相似文献   

Replication of bluetongue virus and epizootic hemorrhagic disease virus in pulmonary artery endothelial cells obtained from cattle,sheep, and deer     

McLaughlin BE  DeMaula CD  Wilson WC  Boyce WM  MacLachlan NJ 《American journal of veterinary research》2003,64(7):860-865

OBJECTIVE: To compare replication of bluetongue virus (BTV) and epizootic hemorrhagic disease virus (EHDV) in pulmonary artery endothelial cells (ECs) obtained from juvenile cattle, sheep, white-tailed deer (WTD; Odocoileus virginianus), and black-tailed deer (BTD; O hemionus columbianus). SAMPLE POPULATION: Cultures of pulmonary artery ECs obtained from 3 cattle, 3 sheep, 3 WTD, and 1 BTD. PROCEDURE: Purified cultures of pulmonary artery ECs were established. Replication, incidence of infection, and cytopathic effects of prototype strains of BTV serotype 17 (BTV-17) and 2 serotypes of EHDV (EHDV-1), and (EHDV-2) were compared in replicate cultures of ECs from each of the 4 ruminant species by use of virus titration and flow cytometric analysis. RESULTS: All 3 viruses replicated in ECs from the 4 ruminant species; however, BTV-17 replicated more rapidly than did either serotype of EHDV. Each virus replicated to a high titer in all ECs, although titers of EHDV-1 were significantly lower in sheep ECs than in ECs of other species. Furthermore, all viruses caused extensive cytopathic effects and a high incidence of cellular infection; however, incidence of cellular infection and cytopathic effects were significantly lower in EHDV-1-infected sheep ECs and EHDV-2-infected BTD ECs. CONCLUSIONS AND CLINICAL RELEVANCE: There were only minor differences in replication, incidence of infection, and cytopathic effects for BTV-17, EHDV-1, or EHDV-2 in ECs of cattle, sheep, BTD, and WTD. It is not likely that differences in expression of disease in BTV- and EHDV-infected ruminants are attributable only to species-specific differences in the susceptibility of ECs to infection with the 2 orbiviruses.  相似文献   

Hypofractionated radiation therapy for the treatment of malignant melanoma and squamous cell carcinoma in dogs and cats     

Kinzel S  Hein S  Stopinski T  Koch J  Buecker A  Treusacher HP  Schmachtenberg A  Jansen T  Eble M  Küpper W 《Berliner und Münchener tier?rztliche Wochenschrift》2003,116(3-4):134-138

This study describes the experience with hypofractionated radiation therapy of squamous cell carcinoma and melanoma in dogs and cats. A total dose of 32-48 Gray (Gy) was delivered once a week in 8 Gy fractions. 34 animals in which a complete surgical excision was impossible were treated. There was no tumor detectable macroscopically in 14 patients at the beginning of radiation therapy. In 20 animals the median volume of the tumor was 9.9 cm3. The median survival times and the local tumor control of squamous cell carcinoma of the oral and nasal cavities and of the body are comparable to results which were reached with a Monday-Wednesday-Friday scheme. For the treatment of Melanoma the hypofractionated radiation therapy is first choice. There are no significant side effects. Late side effects did not occur. 88% of the owners are satisfied with this kind of treatment and would choose it again.  相似文献   

Usefulness of serological examinations in the analysis of Salmonella infections in pig herds     

Steinbach G  Kröll U  Meyer H  Methner U 《Berliner und Münchener tier?rztliche Wochenschrift》2003,116(7-8):281-287

The development of the antibody concentration against lipopolysaccharide (LPS) of S. Typhimurium und S. Choleraesuis in rearing pigs during the fattening period and in breeding sows of the corresponding age was recorded. The studies revealed the following results. Antibodies of isotypes IgG1 and IgG2 revealed a more pronounced specificity against the according Salmonella serovar than IgM antibodies. The calculated "antibody percent value" based on the total amount of Salmonella antibodies is mainly determined by the IgM antibodies in sera and meat juice, respectively. In fattening pigs a significant increase of antibodies against IgM and total Ig was observed between week 3 and 10 after beginning of the rearing period. In breeding pigs this increase was detectable already earlier. In only 3 out of 10 groups an increase of IgG1 and IgG2 was also seen. The detected significant increase of total Ig and IgM in the other groups might be the result of a less intensive exposure to salmonellas or it might be due to an increase of unspecific antibodies induced by other antigens. Serological investigations represent a valuable tool to record the intensity and development in time of the Salmonella exposure in pigs farms. Examination of total Ig is an appropriate method to detect pig herds with a high level of Salmonella exposure, for detailed epidemiological studies in pig farms the examination of antibody isotypes will give more comprehensive information.  相似文献   

Compendium of the history of veterinary anatomy of Rumania: for the 100th birthday of one of their most famous anatomists,Vasile Ghetie     

König HE 《Historia medicinae veterinariae》2003,28(2):54-63

The lessons of veterinary anatomy, firstly it was called "Zootomie", began in Rumania in 1853 and took place at educational establishments for ambulances and at schools for human medicine. The first veterinary school of the country was opened at the 16th of May 1861. The academically trained anatomy began with Prof. Constantin Gavrilescu. The most famous representative of anatomy was Prof. Vasile Ghetie (1903-1990). His act of life positions him beside the great anatomists of the gone century Schmaltz, Barone and Grau.  相似文献   

Spontaneous femoral capital physeal fractures in adult cats: 26 cases (1996-2001)     

McNicholas WT  Wilkens BE  Blevins WE  Snyder PW  McCabe GP  Applewhite AA  Laverty PH  Breur GJ 《Journal of the American Veterinary Medical Association》2002,221(12):1731-1736

OBJECTIVE: To determine clinical, radiographic, and histologic abnormalities in adult cats > 1 year old with spontaneous (ie, nontraumatic) femoral capital physeal fractures. DESIGN: Retrospective study. ANIMALS: 26 cats. PROCEDURE: Medical records of cats > 1 year old with femoral capital physeal fractures and no history of trauma were examined. RESULTS: Mean +/- SD age of the cats was 22.5 +/- 6.5 months. Twenty-five cats were neutered males. Mean weight of the cats was significantly greater than mean weight of a group of age- and sex-matched control cats. Of 16 cats for which age at the time of neutering was known, 14 had been neutered before 6 months of age. Nine cats had bilateral fractures. Severity of femoral neck osteolysis and sclerosis increased with increased duration of clinical signs. The contralateral femoral capital physis, distal femoral physes, and proximal tibial physes were radiographically open in 13 of 18,19 of 24, and 24 of 24 cats, respectively. Histologically, the epiphysis contained normal articular cartilage and bone, but attached growth plate cartilage lacked the normal columnar arrangement of chondrocytes. CONCLUSIONS AND CLINICAL RELEVANCE: Results suggested that adult cats with spontaneous femoral capital physeal fractures were most likely to be heavier, neutered males with delayed physeal closure.  相似文献