Late onset cerebellar cortical degeneration in a koala   总被引：1，自引：1，他引：0  

M Kuwamura  F Murai  S Nishioka  M Aoki  F Ohashi  J Yamate  T Kotani  BA Summers 《Australian veterinary journal》2009,87(8):342-344

A 10-year-old male koala started to fall from the tree while sleeping. Subsequently, the koala often fell down while walking and showed a gait abnormality, abnormal nystagmus and hypersalivation. At 12 years of age, the koala became ataxic and seemed blind. At 13 years of age, the koala exhibited signs of dysstasia and was euthanased. Necropsy revealed marked symmetrical atrophy of the cerebellum. Histopathologically, a severe loss of Purkinje and granule cells was evident in the cerebellum, while the molecular layer was more cellular than normal with cells resembling small neurons, which were positively stained with parvalbumin immunohistochemistry. Reactive Bergmann glial cells (astrocytes) were present adjacent to the depleted Purkinje cell zone. The very late onset and slow progression of the cerebellar cortical degeneration in this case is particularly interesting and appears to be the first report in the koala.  相似文献   

Clinical trial of efficacy of ivermectin pour‐on against gastrointestinal parasitic nematodes in silvopasturing horses     

I. FRANCISCO  J. A. SÁNCHEZ  F. J. CORTIÑAS  R. FRANCISCO  E. MOCHALES  M. ARIAS  P. MULA  J. L. SUÁREZ  P. MORRONDO  P. DÍEZ‐BAÑOS  R. SÁNCHEZ‐ANDRADE  A. PAZ‐SILVA 《Equine veterinary journal》2009,41(7):713-715

The aim of this study was to assess, by a clinical trial, the efficacy of an ivermectin‐based pour‐on treatment against gastrointestinal parasitic nematodes in naturally infected horses using 2 groups of mature indigenous Pura Raza Galega grazing mares. Faecal and blood samples were collected individually over a 21 week period. Faeces were analysed by the coprological flotation, sedimentation and migration techniques. Changes in circulating blood cells were monitored over the study period. The administration of the ivermectin suppressed the eggelimination of ascarids and pinworms throughout the study and no strongyle‐eggs were observed in the treatment group between the 3rd and 10th weeks. The numbers of red cells increased significantly after the anthelmintic therapy, and a statistical reduction in circulating leucocytes was recorded. No side effects were observed. The pour‐on ivermectin formulation was highly successful against gastrointestinal nematodes and appears to be a useful therapeutic routine for large groups of horses.  相似文献   

Interobserver Repeatability of Measurements on Computed Tomography Images of Lax Canine Hip Joints from Youth to Maturity     

MANDI J. LOPEZ DVM  MS  PhD  Diplomate ACVS  KECHIA M. DAVIS DVM  Diplomate ACVS  SUSAN L. JEFFREY‐BORGER BA  MS  DVM  MARK D. MARKEL DVM  PhD  Diplomate ACVS  CHRISTY RETTENMUND DVM 《Veterinary surgery : VS》2009,38(8):920-926

Objectives— To determine interobserver repeatability of measurements on computed tomography (CT) images of lax canine hip joints at different ages and in the presence of degenerative joint disease at maturity. Study Design— Longitudinal observational investigation. Animals— Sibling crossbreed hounds. Methods— Pelvic CT was performed at 20, 24, 32, 48, 68, and 104 weeks of age. Measures were performed on 3 contiguous two‐dimensional (2D) transverse CT images of both hips at each time point by 3 investigators. Center‐edge angle (CEA), horizontal toit externe angle (HTEA), ventral (VASA), dorsal (DASA), and horizontal (HASA) acetabular sector angles, acetabular index (AI), and percent femoral head coverage (CPC) were measured. Interobserver repeatability was quantified with the intraclass correlation coefficient (ICC). Satisfactory repeatability was considered when ICC≥0.75. Results— DASA, CEA, and CPC were repeatable in all age groups. HASA and HTEA were repeatable for all but 1 time point. At 20 weeks of age, all measures but AI were repeatable, and at 104 weeks of age, DASA, CEA, CPC, and HASA were repeatable. Measures were repeatable in hips with and without degenerative changes with the exceptions of AI and HASA in normal hips and VASA and HTEA in osteoarthritic hips. Conclusions— Most 2D CT measurements examined were repeatable regardless of age or joint disease. Clinical Relevance— Two‐dimensional CT measures may augment current techniques for assessing joint changes in lax canine hips.  相似文献   

Antinociceptive, cardiopulmonary, and sedative effects of five intravenous infusion rates of lidocaine in conscious dogs     

Lori M MacDougall DVM    James A Hethey BSc    Alex Livingston† BSc  BVetMed  PhD  Diplomate ECVPT  FRCVS    Christopher Clark‡ BA  VetMB  MVetSc  Diplomate ACVIM    Cindy L Shmon DVM  MVSc  Diplomate ACVS  & Tanya Duke-Novakovski BVetMed  DVA  Diplomate ACVA  Diplomate ECVAA 《Veterinary anaesthesia and analgesia》2009,36(5):512-522

  相似文献   

玉米浸泡和粉碎对绵羊日粮消化的影响     

巴  布日格旦  雒秋江  谢文龙  潘榕 《新疆农业科学》2021,58(11):2133-2138

【目的】比较浸泡和粉碎2种不同加工方式的玉米粒对绵羊的自由采食和消化的影响。为提高绵羊对玉米颗粒的消化和饲养提供参考依据。【方法】选取6只3岁、体重为(55.0±3.8)kg的健康小尾寒羊公羊,随机分为3组,每组2只。按照3×3拉丁方设计,在3个试验期给各组绵羊分别饲喂组成相同(70%混合精料+30%粉碎玉米秸秆,其中玉米含量55%)、但玉米处理不同的日粮(1、2和3),即整粒玉米为对照组(日粮1)、粉碎玉米(日粮2)、浸泡60~72 h的整粒玉米(日粮3)。【结果】3种日粮的干物质自由采食量分别为(1 566.9±121.6)、(1 579.6±98.5)和(1 466.1±101.2)g/羊/d,日粮3比日粮1和2分别显著降低6.4%(P<0.05)和7.2%(P<0.05)。干物质表观消化率分别为(57.92±0.63)、(62.63±0.53)和(66.39±0.75)%,日粮3比日粮1和2分别显著增加14.6%(P<0.05)和6.0%(P<0.05)。干物质消化量分别为(907.5±59.4)、(989.3±92.5)和(953.4±78.5)g/羊/d,日粮3比日粮1和2分别显著增加5.0%(P<0.05)和减少3.6%(P<0.05)。但日粮3和日粮2比日粮1粗纤维消化率和消化量均无显著差异(P > 0.05)。【结论】日粮中使用浸泡玉米饲喂绵羊会降低绵羊的自由采食量,但同时会提高绵羊的表观消化率,表明浸泡玉米饲喂更有利于促进绵羊的消化。  相似文献   

小麦生理型雄性不育系中反式烯脂酰-CoA还原酶基因(TaECR)的克隆及表达分析     

巴青松  张改生  车会学  刘红占  张龙雨  王书平 《农业生物技术学报》2013,21(7)

超长链脂肪酸(VLCFAs)代谢在花药发育中发挥着重要的作用,而反式烯脂酰-CoA还原酶(trans-2,3-enoyl-CoA reductase,ECR)是催化超长链脂肪酸合成的脂肪酰-CoA延长酶之一.为进一步研究杀雄剂SQ-1诱导小麦雄性不育的机理,根据己报道二穗短柄草(Brachypodium distachyon)ECR基因,采用电子克隆获得序列并设计引物,从小麦(Triticum aestivum)中克隆ECR的开放阅读框cDNA序列,命名为TaECR,将该序列提交至GenBank,登录号为KC222053.序列分析表明,TaECR基因编码310个氨基酸,具有反式烯脂酰-CoA还原酶的经典结构域.表达分析表明,TaECR基因在小麦花药、颖片、叶和根中均有表达,其中在根中的表达量最底;与可育系相比,TaECR基因在生理型不育系三核期中表达急剧下调,在单核期和二核期表达趋势无显著变化,并与其蜡质积累量变化趋势基本一致,这表明TaECR基因调节的超长链脂肪合成途径可能参与了SQ-1诱导的败育过程.  相似文献   

小灰水浸提液处理青稞秸秆后在瘤胃中消失率的变化特点     

田发益  袁雷  巴平  李晓忠  钟国辉 《畜牧与兽医》2012,44(7):32-36

西藏饲草资源有限,牛羊生产性能低,特别是冬春季节,牛羊多处于半饥饿状态。提高西藏牛羊对饲草的利用率,是西藏牛羊养殖业的重要目标之一。本试验选用西藏农牧民最常用的燃料-牛粪灰,按一定的比例水浸提牛粪灰中的碱性物质和矿物质,再按一定的比例浸泡装入青稞秸秆的无纺布滤袋内,置入羊瘤胃内测定对主要物质的消失率。结果表明:牛粪灰中K+含量较高,达到(28.4594±1.6483)mg/g,Cu2+含量为(0.5492±0.0025)mg/g,同时含有大量的其他微量元素及CO32-盐和PO43-盐。经试验,当灰水比为0.88∶10时,pH值最高,达到10.18。用这一比例灰水浸提液浸泡填入青稞秸秆的滤袋48 h后,消化后再测定总养分、纯纤维素、NDF、ADF在瘤胃中的消失率,分别显著提高了4.45%、4.89%、6.95%和5.80%。由此可见,利用廉价的牛粪灰水浸提液浸泡秸秆能显著地提高纤维素在牛羊瘤胃中的利用率。  相似文献   

两个奶牛场DHI测定效果分析     

蔡涛  白延琴  史天民  徐文华  刘超  辛亚平 《中国牛业科学》2012,38(5):33-36

[目的]DHI(Dairy Herd Improvement牛群改良)牛奶测定技术是奶牛饲养的核心技术,旨在加强牧场的管理基础和遗传基础,提高奶牛生产的产量、质量和效率。本文在西北农林科技大学教学实验奶牛场和西安草滩奶牛一场进行了DHI测定。[方法]对DHI报表中体细胞数、乳脂率、乳蛋白率、产奶量四项基本测定内容进行了分析。[结果]表明,西安草滩奶牛一场奶牛乳中体细胞数(35.0万个/mL42.0万个/mL)和产奶高峰日(89.30d66.20d)均大于校实验牛场。[结论]西安草滩奶牛一场脂蛋比低于正常水平(F/P1.12),校实验牛场脂蛋比高于正常水平(F/P1.12)。  相似文献   

荷斯坦牛生产体内性控胚胎的试验研究     

巴特尔  孙伟  苏和  郭继彤  李喜和 《中国奶牛》2012,(11):22-25

本研究采用荷斯坦牛X-性控冻精和超数排卵技术生产奶牛体内性控胚胎。结果显示,使用阴道栓(Cue-Mate)对31头供体奶牛进行同期发情处理,发情率为100%,且发情时间较集中。31头供体奶牛共回收胚胎321枚,头均回收胚胎10.35枚,其中可用胚胎225枚,头均可用胚胎7.26枚。选择36头黄牛受体进行单胚移植,其中21头移植鲜胚,妊娠10头,妊娠率47.62%;15头移植冻胚,妊娠6头,妊娠率40.00%。  相似文献   

中职与高职衔接：西藏高职教育可持续发展必由之路     

巴果  卢金金  相理锋 《中国农业教育》2012,(4):23-27

提高技能型人才培养的社会适应性是西藏中高职衔接的主要目标。基于对于高职衔接基本内涵的把握,结合中高职衔接的理论和现实依据,西藏可持续发展高职教育的重要途径,一是借鉴国内外成功经验,选择适合西藏高职发展的学制衔接模式;二是结合藏区职教发展现状,探索贯穿西藏职业教育的要素衔接途径。  相似文献