Light and electron microscopic evaluation of canine corneal endothelium following CO₂ photokeratotomy     

Allison Hoffman  Charlotte Ownby†  Terry W. Lehenbauer†  Don Samuelson§  Margi Gilmour†  Kenneth Bartels† 《Veterinary ophthalmology》2009,12(S1):28-34

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Rights‐based fisheries governance: from fishing rights to human rights     

Edward H Allison  Blake D Ratner  Björn Åsgård  Rolf Willmann  Robert Pomeroy  John Kurien 《Fish and Fisheries》2012,13(1):14-29

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What is your diagnosis? Skin scraping from a hellbender          下载免费PDF全文

Allison Dusick  Bente Flatland  Linden Craig  Sylvia Ferguson 《Veterinary clinical pathology / American Society for Veterinary Clinical Pathology》2017,46(1):183-184

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Use of palatable medicines     

Gleadhill A 《The Veterinary record》2010,167(15):587; discussion 587-587; discussion 588

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Pathology in practice. Ranavirus infection     

Ruder MG  Allison AB  Miller DL  Keel MK 《Journal of the American Veterinary Medical Association》2010,237(7):783-785

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Improvement of Fertility in Artificially Inseminated Ewes Following Vaginal Treatment with Misoprostol Plus Terbutaline Sulphate     

AEM Horta  JP Barbas  CC Marques  MC Baptista  MI Vasques  RM Pereira  RD Mascarenhas  S Cavaco‐Gonçalves 《Reproduction in domestic animals》2010,45(6):e412-e416

The effect of vaginal administration of misoprostol plus terbutaline sulphate 6 h prior to artificial insemination (AI) upon the site of AI (vaginal or cervical) and fertility was studied using a total of 87 estrous synchronized Serra da Estrela ewes (control n = 42 and treated n = 45). Artificial insemination was performed using refrigerated semen at 54–55 h after sponge removal. Lambing rate (fertility) and prolificacy were compared between control and treated ewes. The effect of the site of semen deposition on fertility was also evaluated. Prolificacy rate was not different between control (1.5) and treated (1.59) ewes. The proportion of cervical AI achieved in control (45.2%) and treated (37.8%) ewes was not significantly different. Overall, fertility was significantly lower in control than in treated ewes (42.9% vs 64.4%; p < 0.04). Fertility following vaginal AI was significantly lower for control for than treated ewes (30.4% vs 60.7%; p < 0.03) but the difference was smaller and not significant for cervical AI (control 57.9% vs 70.6%). It was concluded that vaginal administration of misoprostol plus terbutaline sulphate 6 h prior to artificial insemination did not affect the proportion of cervical inseminations but significantly improved the fertility of treated ewes. Although needing confirmation, it was hypothesized that drugs might have induced local secretory modifications leading to an increase of cervical ability to retain more viable spermatozoa for fertilization.  相似文献   

Clinical presentation of 26 anaplasma phagocytophilum-seropositive dogs residing in an endemic area     

Mazepa AW  Kidd LB  Young KM  Trepanier LA 《Journal of the American Animal Hospital Association》2010,46(6):405-412

Anaplasma (A.) phagocytophilum, the etiological agent of canine granulocytic anaplasmosis, is capable of inciting moderate to severe clinical disease in a variety of mammals and is endemic in the upper midwest. The purpose of this study was fourfold: to describe the range of clinical signs in dogs seropositive to A. phagocytophilum; to examine the prevalence of immune-mediated hemolytic anemia (IMHA) in this population; to evaluate whether specific clinical signs were associated with coexposure to Borrelia (B.) burgdorferi in actively infected dogs; and to determine whether clinical response to doxycycline was complete in treated dogs. Medical records of dogs seropositive for A. phagocytophilum were reviewed retrospectively. Peripheral blood smears were also reviewed retrospectively for granulocytic Anaplasma morulae. Lethargy (81%), inappetence (58%), and lameness (50%) were the most common clinical signs, followed by fever (46%). Thrombocytopenia was the most common laboratory abnormality, and IMHA was diagnosed in three dogs. Dogs that were thrombocytopenic and had antibodies to both A. phagocytophilum and B. burgdorferi had a median platelet count of 51,000/μL (range 20,000 to 171,000/μL), which was significantly lower than the count in dogs with antibodies only to A. phagocytophilum (P=0.04). Some dogs had an apparent relapse of clinical signs after an appropriate course of doxycycline. Testing for A. phagocytophilum by polymerase chain reaction, serum antibody assays, and/or blood smear evaluation should be considered in dogs with IMHA, cough, or epistaxis and that reside in A. phagocytophilum-endemic areas. If moderate to severe thrombocytopenia is present, testing for concurrent B. burgdorferi infection may be warranted.  相似文献   

Collaborative non-self recognition system in S-RNase-based self-incompatibility   总被引：6，自引：0，他引：6  

Kubo K  Entani T  Takara A  Wang N  Fields AM  Hua Z  Toyoda M  Kawashima S  Ando T  Isogai A  Kao TH  Takayama S 《Science (New York, N.Y.)》2010,330(6005):796-799

Self-incompatibility in flowering plants prevents inbreeding and promotes outcrossing to generate genetic diversity. In Solanaceae, a multiallelic gene, S-locus F-box (SLF), was previously shown to encode the pollen determinant in self-incompatibility. It was postulated that an SLF allelic product specifically detoxifies its non-self S-ribonucleases (S-RNases), allelic products of the pistil determinant, inside pollen tubes via the ubiquitin-26S-proteasome system, thereby allowing compatible pollinations. However, it remained puzzling how SLF, with much lower allelic sequence diversity than S-RNase, might have the capacity to recognize a large repertoire of non-self S-RNases. We used in vivo functional assays and protein interaction assays to show that in Petunia, at least three types of divergent SLF proteins function as the pollen determinant, each recognizing a subset of non-self S-RNases. Our findings reveal a collaborative non-self recognition system in plants.  相似文献   

Long‐term outcome after implantation of a suprachoroidal cyclosporine drug delivery device in horses with recurrent uveitis     

Brian C. Gilger  David A. Wilkie  Allison B. Clode  Richard J. McMullen  Mary E. Utter  Andras M. Komaromy  Dennis E. Brooks  Jacklin H. Salmon 《Veterinary ophthalmology》2010,13(5):294-300

Objective To determine the long‐term efficacy, complications, and duration of effect of a cyclosporine (CsA) suprachoroidal implant (CSI) in horses with equine recurrent uveitis (ERU). Methods Horses with ERU were treated with a 6‐mm diameter, 25 mg, reservoir matrix CsA implant in the deep sclera adjacent to the suprachoroidal space. Horses with follow‐up >1 year were examined for frequency of uveitis episodes, complications, and vision at last recheck. Results Data from 151 eyes of 133 horses from the USA and Europe that had CsA devices implanted for ERU were reviewed. Follow‐up time ranged from 13 to 85 months after surgery, with a mean and median follow‐up time of 28.9 and 26.3 months, respectively. Overall, at last follow‐up 78.8% of eyes were considered visual and the overall mean frequency of uveitis episodes after CSI was 0.09 ± SD 0.08 episodes per month. The most common complications leading to vision loss at last follow‐up were persistent uveitis episodes (54%), glaucoma (22%), mature cataracts (16%), and retinal detachment (6%). Persistent uveitis episodes tended to be the highest cause of vision loss in horses with <24 months and >48 months of follow‐up. Conclusions This study demonstrated the long‐term maintenance of vision of horses with ERU implanted with a CSI. The increased vision loss related to uveitis episode of inflammation in eyes after the likely depletion of CsA from the CSI suggests that a repeat CSI may be required at or before 48 months after surgery.  相似文献   

A refresher in research publication ethics     

Hodge A  Haapala I  Yngve A  McNeill G  Tseng M 《Public health nutrition》2012,15(3):377-378

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