Malignant Sertoli Cell Tumour in a Young Simmenthal Bull – Clinical and Pathological Observations     

KL Jensen  L Krag  GB Boe‐Hansen  HE Jensen  H Lehn‐Jensen 《Reproduction in domestic animals》2008,43(6):760-763

Tumours are rare in the bovine testicle. A case of malignant Sertoli cell tumour in a 29‐month‐old Simmenthal bull that was hospitalized with a history of severe unilateral scrotal swelling is reported. On inspection and palpation, the scrotal sac was found enlarged with fluctuant content in the right side. The right testicle was enlarged, hard and indolent. Also the right plexus pampiniformis and funiculus spermaticus were enlarged. Sonograms revealed severe changes in the right testicle with a loss of homogeneity and multiple hyperechogenic areas. After slaughter, the scrotum with testicles were removed and evaluated pathologically. On section, the right testicle contained areas of necrosis, haemorrhage, and mineralization. Histology showed Sertoli cells in tubular structures surrounded by dense fibrous stroma replacing normal testicular tissue. Both lymphatic and blood vessels were infiltrated by neoplastic cells. Immunohistochemically, the neoplastic cells stained positive for vimentin and negative for cytokeratin and S‐100. Based on the pathological observations a diagnosis of right‐sided malignant Sertoli cell tumour with vascular invasion and hydrocele was established.  相似文献   

Neuropharmacological effects of deltamethrin in rats     

S. Manna  D. Bhattacharyya  T. K. Mandal  S. Dey 《Journal of veterinary science (Suw?n-si, Korea)》2006,7(2):133-136

This study examined the effect of deltamethrin on some of the neuropharmacological paradigms in a rat brain such as the motor co-ordination test using a rotarod, the pentobarbitone-induced sleeping time and pentylenetetrazole (PTZ)-induced convulsion as well as the gamma aminobutyric acid (GABA) level. Albino Wistar rats were used as the experimental animals. Different neuropharmacological paradigms such as the motor co-ordination by the rotarod, pentobarbitone-induced sleeping time and the PTZ-induced convulsion were examined after administering deltamethrin orally at two doses, 150 mg/kg (LD₅₀) and 15 mg/kg (1/10 LD₅₀). The GABA level in the rat brain was estimated by HPLC after a single oral dose of 150mg/kg deltamethrin. Deltamethrin significantly reduced the motor coordination, decreased the onset time and increased the sleeping time duration induced by pentobarbitone. In addition, it also decreased the onset time and increased the duration of convulsions induced by PTZ at 150 mg/kg (LD₅₀) and 15 mg/kg (1/10 LD₅₀), respectively. Further deltamethrin administration decreased the GABA levels in the cerebellum as well as in the whole brain (except the cerebellum) significantly at the LD₅₀ dose level. There was some correlation between the effect of deltamethrin on the central GABA levels and its neuropharmacological effects.  相似文献   

Poisoning of feedlot cattle by seeds of Heliotropium europaeum     

BD HILL  KL GAUL  JW NOBLE 《Australian veterinary journal》1997,75(5):360-361

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A clinical trial of a topical preparation of miconazole, polymyxin and prednisolone in the treatment of otitis externa in dogs   总被引：3，自引：0，他引：3  

VP STUDDERT  KL HUGHES 《Australian veterinary journal》1991,68(6):193-195

A topical preparation containing miconazole, polymyxin and prednisolone was shown to be more effective in the treatment of otitis externa in 167 dogs than 2 other ear preparations containing antibiotics, an antimycotic and a corticosteroid. With miconazole, polymyxin and prednisolone, the recurrence rate was 26.7% compared with 72.6% and 54.3% when the other products were used. The mean duration of treatment required to achieve resolution of clinical signs was 9.6 days, compared with 12.2 days and 13.0 days and no cases failed to respond to treatment, compared with 17.7% and 14.3%. Malassezia canis alone (71%) or in association with bacteria (18%) was recovered from 44 of 49 ears cultured.  相似文献   

Prüfung der coccidiostatischen Wirksamkeit von Coyden 25®1 auf Eimeria tenella durch quantitative Bestimmung der Blutmenge in den Blinddärmen mit Hilfe Fe59-markierter Erythrozyten     

K. Enigk  H. Schanzel  A. Dey Hazra 《Zoonoses and public health》1968,15(9):984-989

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Therapeutic responses of piglets to experimentally induced colibacillosis.     

B P Dey  D C Blenden  G C Burton  H E Mercer  R K Tsutakawa 《Research in veterinary science》1977,23(3):340-343

The purpose of these experiments was to determine the effects of prior exposure to antimicrobials on subsequent treatment of artificially induced colibacillosis in pigs. One- to two-week-old piglets were given 10(7) multiple antibiotic resistant Escherichia coli orally. Two groups of the piglets received priming doses at different levels of the antimicrobial preparation, ASP-250 before challenge. The remaining group received no antimicrobial. Piglets ill as a result of the challenge were treated with chloramphenicol of chlortetracycline, or received no treatment. Chloramphenicol was significantly more effective than chlortetracycline in terminating colibacillosis in the primed and unprimed groups. There were fewer deaths and relapse cases in those groups which received chloramphenicol treatment. Results in piglets treated with chlortetracycline were not significantly better than those which received no treatment.  相似文献   

Effect of initial seedling size,understory competition,and overstory density on the survival and growth of Pinus echinata seedlings underplanted in hardwood forests for restoration     

John M. Kabrick  Benjamin O. Knapp  Daniel C. Dey  David R. Larsen 《New Forests》2015,46(5-6):897-918

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Effect of Tree Diversity on Soil Organic Carbon Content in the Homegarden Agroforestry System of North-Eastern Bangladesh     

Islam  Mahmuda  Dey  Anna  Rahman  Mizanur 《Small-Scale Forestry》2015,14(1):91-101

Small-scale Forestry - Tropical agroforestry systems have immense potential to sequester carbon both in aboveground and belowground biomass and soil. Homegarden agroforestry is a popular land-use...  相似文献   

Canine superficial bacterial pyoderma: evaluation of skin surface sampling methods and antimicrobial susceptibility of causal Staphylococcus isolates     

PA Ravens  LJ Vogelnest  E Ewen  KL Bosward  JM Norris 《Australian veterinary journal》2014,92(5):149-155

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Solvent tuning of electrochemical potentials in the active sites of HiPIP versus ferredoxin     

Dey A  Jenney FE  Adams MW  Babini E  Takahashi Y  Fukuyama K  Hodgson KO  Hedman B  Solomon EI 《Science (New York, N.Y.)》2007,318(5855):1464-1468

A persistent puzzle in the field of biological electron transfer is the conserved iron-sulfur cluster motif in both high potential iron-sulfur protein (HiPIP) and ferredoxin (Fd) active sites. Despite this structural similarity, HiPIPs react oxidatively at physiological potentials, whereas Fds are reduced. Sulfur K-edge x-ray absorption spectroscopy uncovers the substantial influence of hydration on this variation in reactivity. Fe-S covalency is much lower in natively hydrated Fd active sites than in HiPIPs but increases upon water removal; similarly, HiPIP covalency decreases when unfolding exposes an otherwise hydrophobically shielded active site to water. Studies on model compounds and accompanying density functional theory calculations support a correlation of Fe-S covalency with ease of oxidation and therefore suggest that hydration accounts for most of the difference between Fd and HiPIP reduction potentials.  相似文献