Oncology Virtual Issue Articles     

B. A. Valentine  R. J. Bildfell  A. J. Dunn 《Equine Veterinary Education》2014,26(6):328-328

The following two articles have been published online as part of the EVE Oncology Virtual Issue which is available online at wileyonlinelibrary.com/journal/eve  相似文献   

A Large‐scale,Rapid Public Health Response to Rabies in an Organ Recipient and the Previously Undiagnosed Organ Donor     

R. M. Wallace  D. Stanek  S. Griese  D. Krulak  N. M. Vora  L. Pacha  V. Kan  M. Said  C. Williams  T. H. Burgess  S. S. Clausen  C. Austin  J. Gabel  M. Lehman  L. N. Finelli  G. Selvaggi  P. Joyce  F. Gordin  D. Benator  A. Bettano  S. Cersovsky  C. Blackmore  S. V. Jones  B. D. Buchanan  A. I. Fernandez  D. Dinelli  K. Agnes  A. Clark  J. Gill  M. Irmler  D. Blythe  K. Mitchell  T. J. Whitman  M. J. Zapor  S. Zorich  C. Witkop  P. Jenkins  P. Mora  D. Droller  S. Turner  L. Dunn  P. Williams  C. Richards  G. Ewing  K. Chapman  C. Corbitt  T. Girimont  R. Franka  S. Recuenco  J. D. Blanton  K. A. Feldman 《Zoonoses and public health》2014,61(8):560-570

This article describes and contrasts the public health response to two human rabies cases: one organ recipient diagnosed within days of symptom onset and the transplant donor who was diagnosed 18 months post‐symptom onset. In response to an organ‐transplant‐related rabies case diagnosed in 2013, organ donor and recipient investigations were conducted by multiple public health agencies. Persons with potential exposure to infectious patient materials were assessed for rabies virus exposure. An exposure investigation was conducted to determine the source of the organ donor's infection. Over 100 persons from more than 20 agencies spent over 2700 h conducting contact investigations in healthcare, military and community settings. The 564 persons assessed include 417 healthcare workers [5.8% recommended for post‐exposure prophylaxis (PEP)], 96 community contacts (15.6% recommended for PEP), 30 autopsy personnel (50% recommended for PEP), and 21 other persons (4.8% recommended for PEP). Donor contacts represented 188 assessed with 20.2% recommended for PEP, compared with 5.6% of 306 recipient contacts recommended for PEP. Human rabies cases result in substantial use of public health and medical resources, especially when diagnosis is delayed. Although rare, clinicians should consider rabies in cases of encephalitis of unexplained aetiology, particularly for cases that may result in organ donation.  相似文献   

Nitrogen requirement of pregnant gilts     

J M Dunn  V C Speer 《Journal of animal science》1991,69(5):2020-2025

Eleven Yorkshire x Landrace gravid gilts were used in two Latin square trials to determine the N requirement for pregnancy. Semipurified diets were formulated to be adequate in indispensable amino acids (IAA) and other nutrients. Diets were fed once daily (1.82 kg); L-glutamic acid, corn sugar, powdered cellulose, and soybean oil percentages differed to maintain isocaloric diets. In Trial 1, six gilts were fed diets containing 6.6 to 17.2% CP equivalent (19.2 to 50.1 g of N/d) during six 10-d periods beginning on d 40 postcoitum. In Trial 2, five gilts were fed diets containing 4.3 to 12.6% CP equivalent (12.5 to 36.8 g of N/d) during five 10-d periods beginning on d 50 postcoitum. Nitrogen balance trials were conducted during the last 5 d of each period. Blood samples were taken both before and 3 h after the last feeding of each period. Results from Trial 1 suggested that adequate N retention (10 g/d) could be attained by pregnant gilts fed less than 28 g of N/d intake when the diet contained indispensible amino acids at levels suggested by Nutrient Requirements of Swine (NRC, 1988). An intake of 20.6 g of N/d (7.1% CP equivalent) yielded near maximum N retention among pregnant gilts fed the semipurified diets in Trial 2. Other criteria measured (urine urea nitrogen and plasma urea nitrogen) had limited value in the evaluation of the N status of the pregnant gilts in these trials.  相似文献   

Induction of ovulation in proestrous ewes: Identification of the ovulatory follicle and functional status of the corpus luteum     

A.J. Roberts  T.G. Dunn  W.J. Murdoch 《Domestic animal endocrinology》1985,2(4):207-210

Ewes were treated with a luteolytic agent on Day 14 of the estrous cycle. Their largest follicle was identified 30 hr later. Thirty-six hr post-treatment, ewes received an injection of an analog of luteinizing hormone-releasing hormone (LHRHa). The peak in the induced surge of LH occurred 2 to 4 hr after injection of LHRHa. Ovulation occurred from the largest follicle approximately 24 hr following administration of LHRHa. During the subsequent luteal phase, serum concentrations of progesterone were normal. The treatment regimen described is well-suited for collection of follicles at precisely-timed periovulatory intervals. Perhaps information gained by using this model will be useful in ultimately understanding the follicular events associated with ovulation and function of the corpus luteum.  相似文献   

Metabolism of [14C]mibolerone in the chicken     

G H Dunn  L F Krzeminski  R E Gosline  C J Subacz 《Journal of agricultural and food chemistry》1979,27(5):1001-1006

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Radiation Hazards     

Dunn LC  Dobzhansky T 《Science (New York, N.Y.)》1958,128(3337):1534

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The effect of histone gene deletions on chromatin structure in Saccharomyces cerevisiae   总被引：12，自引：0，他引：12  

D Norris  B Dunn  M A Osley 《Science (New York, N.Y.)》1988,242(4879):759-761

As a way of studying nucleosome assembly and maintenance in Saccharomyces cerevisiae, mutants bearing deletions or duplications of the genes encoding histones H2A and H2B were analyzed. Previous genetic analysis had shown that only one of these mutants exhibited dramatic and pleiotropic phenotypes. This mutant was also the only one that contained disrupted chromatin, suggesting that the original phenotypes were attributable to alterations in chromosome structure. The chromatin disruption in the mutant, however, did not extend over the entire genome, but rather was localized to specific regions. Thus, while the arrangement of nucleosomes over the HIS4 and GAL1 genes, the telomeres, and the long terminal repeats (delta sequences) of Ty retrotransposons appeared essentially normal, nucleosomes over the CYH2 and UBI4 genes and the centromere of chromosome III were dramatically disrupted. The observation that the mutant exhibited localized chromatin disruptions implies that the assembly or maintenance of nucleosomes differs over different parts of the yeast genome.  相似文献   

Polar motion from laser tracking of artificial satellites     

Smith DE  Kolenkiewicz R  Dunn PJ  Plotkin HH  Johnson TS 《Science (New York, N.Y.)》1972,178(4059):405-406

Measurements of the range to the Beacon Explorer C spacecraft from a single laser tracking system at Goddard Space Flight Center have been used to determine the change in latitude of the station arising from polar motion. A precision of 0.03 arc second was obtained for the latitude during a 5-month period in 1970.  相似文献   

EFFECT OF DRY STORAGE ON THE ANTIRACHITIC POTENCY OF COD LIVER OIL     

Dunn LC 《Science (New York, N.Y.)》1924,59(1535):485-486

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THE RELATION OF ELECTRICAL ENGINEERING TO OTHER PROFESSIONS     

Dunn G 《Science (New York, N.Y.)》1912,36(919):161-166

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