Effects of Exogenous Insulin on Luteolysis and Reproductive Cyclicity in the Mare     

BPB Rambags  AW van Rossem  EE Blok  E de Graaf-Roelfsema  H Kindahl  JH van der Kolk  TAE Stout 《Reproduction in domestic animals》2008,43(4):422-428

Insulin is a pancreatic hormone that classically regulates carbohydrate and fat metabolism, but also appears to play a role in various reproductive processes. A preliminary study suggested insulin production by day 10 to 18 equine conceptuses. The aim of the present study was to examine the hypothesis that insulin is the conceptus signal responsible for maternal recognition of pregnancy (MRP) in the mare, or otherwise influences reproductive cyclicity during the MRP period. Six Warmblood mares were treated daily during days 7 to 17 after ovulation of two successive oestrous cycles with either (short and intermediate acting) insulin or control saline. Mares were assigned randomly to treatment, and crossed over during the subsequent cycle. Time of ovulation and corpus luteum surface area were determined by serial transrectal ultrasonographic examination of the mares' ovaries, and daily jugular vein blood samples were analysed for progesterone and luteinizing hormone (LH) concentrations. On day 14 of dioestrus, the luteolytic drive was examined by measuring systemic 15-ketodihydroprostaglandin F_{2 α} (PG-metabolite) release in response to oxytocin challenge. In addition, yolk sac fluid recovered from 32 day 10 to 14 equine conceptuses was analysed for insulin concentrations. Insulin administration did not affect luteal size, dioestrus length, the interovulatory interval, or circulating LH concentrations. Insulin administration also failed to suppress oxytocin-induced PGF_{2 α} release, and tended to depress systemic progesterone concentrations. Finally, insulin could not be detected in the yolk sac fluid of day 10 to 14 equine conceptuses by radio-immunoassay. It is concluded that insulin administered daily during days 7 to 17 of dioestrus has little or no effect on reproductive cyclicity in the mare, and is unlikely to be the MRP signal.  相似文献   

An outbreak of mucormycosis in slender tree frogs (Litoria adelensis) and white-lipped tree frogs (Litoria infrafrenata)     

JH CREEPER  DC MAIN  L. BERGER  S. HUNTRESS  W. BOARDMAN 《Australian veterinary journal》1998,76(11):761-762

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CD4+ and CD8+ T- lymphocytopenia in a filly with Pneumocystis carinii pneumonia     

MJBF FLAMINIO  BR RUSH  JH COX  WE MOORE 《Australian veterinary journal》1998,76(6):399-402

Decreased proportion of CD4+ and CD8+ T lymphocytes in peripheral blood likely contributed to susceptibility to Pneumocystis carinii in a foal. Cytological evaluation of bronchoalveolar lavage was required for identification of the pathogen and serial flow-cytometric analysis of peripheral blood lymphocytes documented transient low expression of CD4+ and CD8+ T lymphocytes. Although immunodeficiency is uncommon, it must be included in the differential diagnosis for patients suffering from chronic or opportunistic infections and may provide an indication for immunostimulant therapy.  相似文献   

miRNA and piRNA expression profiles of breeder cock testes detected by next‐generation sequencing          下载免费PDF全文

SR Wu  W Guo  YL Li  XC Ren  XY Lei  XY Li  JH Yao  XJ Yang 《Reproduction in domestic animals》2017,52(2):203-213

miRNAs are small non‐coding regulatory RNAs that play key roles in diverse biological processes. In this study, we used the Solexa sequencing technique to profile miRNAs in breeder cock testes to illustrate their functions. A total of 663 co‐expressed miRNAs and 3,180 co‐expressed piRNAs were detected in three libraries. Based on Mir‐X^? miRNA qRT‐PCR, three miRNAs representing low, medium and high expression levels according to the sequencing results were selected randomly to validate the miRNAs' expression profiles. Results suggested that the miRNA expression profiles data could represent actual miRNA expression levels. Moreover, target genes prediction of the co‐expressed miRNAs and further Gene Ontology and Kyoto Encyclopedia of Genes and Genomes analyses were performed, which revealed that some candidate miRNAs were involved in the regulation of the spermatogenesis process, spermatozoa function and testicular metabolism. In conclusion, we provided a useful resource for further elucidation of the miRNAs' regulatory role in spermatogenesis, contributing to a preliminary database for functional and molecular mechanistic studies in testicular metabolism, spermatogenesis and other testes functions.  相似文献   

Demographic and preliminary employment data of the first two graduate cohorts from a rural veterinary school          下载免费PDF全文

JH Hyams  SL Raidal  LM Hayes  J Heller 《Australian veterinary journal》2017,95(4):91-100

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Interactions among forest composition,structure, fuel loadings and fire history: A case study of red pine-dominated forests of Seney National Wildlife Refuge,Upper Michigan     

Igor Drobyshev  P. Charles Goebel  David M. Hix  R. Gregory Corace III  Marie E. Semko-Duncan 《Forest Ecology and Management》2008

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Investigations of the potential risk factors associated with cases of bovine spongiform encephalopathy in Bavaria, Germany     

Clauss M  Sauter-Louis C  Chaher E  Pottgiesser C  Goebel S  Selhorst T  Wichmann HE  Klee W  Kienzle E 《The Veterinary record》2006,158(15):509-513

In order to identify the management and feeding practices that might have contributed to the occurrence of bovine spongiform encephalopathy (BSE) in Bavaria, Germany, information from 110 dairy farms on which a case of BSE had been reported was compared with information derived from a questionnaire sent to approximately 10,000 Bavarian farms on which no case of BSE had been reported up to February 2003. Representative information was obtained from 4006 dairy farms. The results indicated that in comparison with these control farms a higher proportion of the BSE farms had also kept pigs or poultry, although the difference was not significant, and that a significantly higher proportion of the BSE farms had fed proprietary concentrates and/or milk replacers to their calves.  相似文献   

Transcriptome analysis of the uniparous and multiparous goats ovaries          下载免费PDF全文

FY Guo  YJ Zhao  JH Zhang  ZQ Zhao 《Reproduction in domestic animals》2016,51(6):877-885

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Fullerene pipes   总被引：10，自引：0，他引：10  

J Liu  AG Rinzler  H Dai  JH Hafner  RK Bradley  PJ Boul  A Lu  T Iverson  K Shelimov  CB Huffman  F Rodriguez-Macias  YS Shon  TR Lee  DT Colbert  RE Smalley 《Science (New York, N.Y.)》1998,280(5367):1253-1256

Single-wall fullerene nanotubes were converted from nearly endless, highly tangled ropes into short, open-ended pipes that behave as individual macromolecules. Raw nanotube material was purified in large batches, and the ropes were cut into 100- to 300-nanometer lengths. The resulting pieces formed a stable colloidal suspension in water with the help of surfactants. These suspensions permit a variety of manipulations, such as sorting by length, derivatization, and tethering to gold surfaces.  相似文献   

Circular polarization in star- formation regions: implications for biomolecular homochirality     

J Bailey  A Chrysostomou  JH Hough  TM Gledhill  A McCall  S Clark  F Menard  M Tamura 《Science (New York, N.Y.)》1998,281(5377):672-674

Strong infrared circular polarization resulting from dust scattering in reflection nebulae in the Orion OMC-1 star-formation region has been observed. Circular polarization at shorter wavelengths might have been important in inducing chiral asymmetry in interstellar organic molecules that could be subsequently delivered to the early Earth by comets, interplanetary dust particles, or meteors. This could account for the excess of L-amino acids found in the Murchison meteorite and could explain the origin of the homochirality of biological molecules.  相似文献