MAGNETIC RESONANCE IMAGING OF CEREBRAL CORTICAL NECROSIS (POLIOENCEPHALOMALACIA) IN A DOG     

Christopher L.  Mariani  DVM  Simon R.  Platt  BVMS  MRCVS  Susan M.  Newell  DVM  MS  Scott P.  Terrell  DVM  Cheryl L.  Chrisman  DVM  MS  EDS  Roger M.  Clemmons  DVM  PhD 《Veterinary radiology & ultrasound》2001,42(6):524-531

A 3-year-old neutered female mixed breed dog was examined because of severe, generalized seizure activity, tetraparesis, and encephalopathic signs. Cerebrospinal fluid (CSF) evaluation was unremarkable except for a mild increase in protein. Serum and CSF titers for infectious diseases were negative. Magnetic resonance (MR) imaging examination of the brain was performed and lesions were found within the cerebral gray matter of the temporal and parietal lobes. The lesions had increased signal intensity on T1, T2, and proton density-weighted images. There was mild inhomogeneous enhancement following intravenous contrast medium administration. Neurologic status improved and the seizures were well controlled, but the dog never regained normal mentation and euthanasia was performed 10 weeks after initial evaluation. At necropsy, severe cerebral cortical necrosis was found in the regions corresponding to the lesions seen on MR imaging examination. Large numbers of fat-containing macrophages (gitter cells) were found within these areas, and are thought to be responsible for the characteristic hyperintensity seen on the MR images.  相似文献   

Enzyme-linked immunosorbent assay for screening the plasma residues of tetracycline antibiotics in pigs.   总被引：6，自引：0，他引：6  

H J Lee  M H Lee  P D Ryu  H Lee  M H Cho 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2001,63(5):553-556

The recommended therapeutic doses of three kinds of tetracyclines, oxytetracycline (OTC, withdrawal period, 10 days), chlortetracycline (CTC, withdrawal period, 5 days) and tetracycline (TC, withdrawal period, 5 days), were each administered to a group of 15 pigs. Blood was sampled before drug administration and during the withdrawal period. The concentration of tetracyclines in plasma, determined by semi-quantitative ELISA, was compared with that of internal standard (10 ppb as oxytetracycline). The absorbance ratio of internal standard to sample (B/Bs) was employed as an index to determine the tissue residues in pigs. All 45 plasma samples from nontreated pigs showed negative in the residue of any of three tetracycline antibiotics. OTC was detected in plasma of pigs treated until the 8th day, CTC until the 4th day, and TC was detected until the 3rd day of its withdrawal period. The present study showed that the semi-quantitative ELISA easily be adopted in predicting tissue residues for tetracycline antibiotics in live pigs.  相似文献   

Tolerance of halofuginone (Stenorol) by geese (Anser anser f. dom.), flight ducks (Cairina moschata f. dom.) and Peking ducks (Anas platyrhynchos f. dom.)     

K P Behr  H Lüders  C Plate 《DTW. Deutsche tier?rztliche Wochenschrift》1986,93(1):4-8

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Localization of extracellular matrix receptors in ICGN mice, a strain of mice with hereditary nephrotic syndrome.     

K Uchio-Yamada  N Manabe  M Yamaguchi  N Akashi  Y Goto  Y Yamamoto  A Ogura  H Miyamoto 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2001,63(11):1171-1178

Fibrotic degeneration was examined in the kidneys of ICR-derived glomerulonephritis (ICGN) mice, a novel inbred mouse line with a hereditary nephrotic syndrome of unknown etiology considered to be a good model of human idiopathic nephrotic syndrome. In the present study, we histochemically revealed changes in accumulation of extracellular matrix (ECM) components and in localization of integrins, cellular receptors for ECM, in the kidneys of ICGN mice with the progression of renal failure. Excessive accumulation of basement membrane (laminin and collagen IV) and interstitial (type III collagen) ECM components were demonstrated in the glomeruli and tubulointerstitum of ICGN mice. Marked deposition of type I collagen and tenascin was seen only in the glomeruli of ICGN mice but not in those of ICR mice as normal controls. Increased expression of integrin alpha1-, alpha2-, alpha5- and beta1-subunits in glomeruli with fibrotic degeneration and abnormal distribution of alpha6-subunit were noted in the kidneys of ICGN mice. Excessive laminin, a ligand of alpha6beta1-integrin, was demonstrated on the tubular basement membrane, but alpha6-subunit diffusely disappeared on the basal side of the tubular epithelial cells. We presumed that abnormal integrin expression in renal tubules causes epithelial cell detachment, and consequently tubular nephropathy, and results in disorder of ECM metabolism causing excessive accumulation of ECM components in the kidneys of ICGN mice.  相似文献   

Computed tomography of the tarsal joint in clinically normal dogs.     

I M Gielen  L M De Rycke  H J van Bree  P J Simoens 《American journal of veterinary research》2001,62(12):1911-1915

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Risk factors for pet evacuation failure after a slow-onset disaster.   总被引：1，自引：0，他引：1  

S E Heath  A M Beck  P H Kass  L T Glickman 《Journal of the American Veterinary Medical Association》2001,218(12):1905-1910

OBJECTIVE: To determine risk factors for pet evacuation failure during a flood. DESIGN: Cross-sectional survey. SAMPLE POPULATION: 203 pet-owning households in a flooded region. PROCEDURES: Persons under evacuation notice because of a flood were interviewed by use of a random telephone survey. RESULTS: 102 households evacuated with their pets, whereas 101 households evacuated without their pets. Low pet attachment and commitment scores were significantly associated with a greater chance of pet evacuation failure. Risk of pet evacuation failure and lower attachment and commitment scores were also associated with pet management practices prior to the disaster, such as dogs being kept outdoors most of the time or owners not having carriers for their cats. More than 90% of owners made housing arrangements for their pets without assistance. CONCLUSIONS AND CLINICAL RELEVANCE: Predictors of pet evacuation failure are usually present before a disaster strikes and are potentially modifiable. Mitigation of pet evacuation failure should focus on activities that reinforce responsible pet ownership and strengthen the human-animal bond, including socializing dogs, attending dog behavior training classes, transporting cats in nondisaster times, and seeking regular preventive veterinary care. Most pet owners are self-reliant in disasters, and this behavior should be encouraged.  相似文献   

Hepatic Lobe Torsion as a Cause of Colic in a Horse   总被引：2，自引：0，他引：2  

TRACY A. TURNER DVM  MS  Diplomate ACVS    CYNTHIA A. BROWN dvm    JULIA H. WILSON DVM  Diplomate ACVIM    LOIS ROTH DVM  Diplomate ACVP    DIANA S. ROSENSTEIN DVM    CHRISTINE M. SCHWEIZER dvm  KRISTINE A. WOODAMAN dvm 《Veterinary surgery : VS》1993,22(4):301-304

A 14-year-old Arabian gelding was examined for colic. An exploratory celiotomy was subsequently performed and the left lobe of the liver was found to be twisted. The lobe was resected using a TA-90 surgical stapling instrument. Histologic examination of the resected liver indicated portal vein and sinusoid dilation and congestion with blood. There were focal areas of necrosis and bacterial cocci and rods throughout the section. The histologic findings were consistent with hepatic lobe torsion. After surgery, the horse was treated with broad spectrum antibiotics, anti-inflammatory drugs, heparin, and intravenous fluids. The horse recovered without complications, although serum liver enzymes remained elevated for more than 1 week after surgery. Seven months after surgery the horse showed no adverse affects from the disease.  相似文献   

Polysaccharide-induced protection of carp, Cyprinus carpio L., against bacterial infection   总被引：5，自引：0，他引：5  

T. YANO  H. MATSUYAMA  R. E. P. MANGINDAAN 《Journal of fish diseases》1991,14(5):577-582

Abstract. The efficacy of 10 polysaccharides (curdlan, inulin, krestin, laminaran, lentinan, levan, schizophylian, selerogiucan, yeast glucan and zymosan) to enhance protection of carp, Cyprinus carpio L., against bacterial infection was investigated. Carp were intraperitoneally injected with the polysaceharides (2–l0 mgkg^-1) on days 1 and 4, and challenged with Edwardsiella tarda on day 7. Among the polysaccharides tested, lentinan, schizophyllan and scleroglucan, which are l,6-branchcd-β-l,3-glucans, significantly increased the survival rate. They also induced a protective effect against Aeromonas hydrophila at a dose of 5 mg kg^-1. The ability of the polysaccharides to activate the alternative complement pathway (ACP) was examined by incubating the polysaccharides with carp serum and measuring the residual ACP activity. At a final concentration of 0.l mgml^-1, l,6-branched-β-1,3-glucans greatly reduced (76–77%) the ACP activity. Therefore, it is suggested that the protective effect of the l,6-branched-β-1,3-glucans may be associated with the activation of ACP.  相似文献   

A rapid staining method to differentiate the cytostructure of spermatozoa of farm animals     

H. RAY  A. BHATTACHARYYA  A. PAKRASHI 《Australian veterinary journal》1993,70(2):72-73

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苜蓿施用污泥效果的研究Ⅰ对苜蓿生长及元素含量的影响   总被引：5，自引：2，他引：3  

付华  周志宇  张洪荣  李雪瑞  左秀娟 《草业学报》2001,10(4):67-71

将兰州市七里河污水处理厂生活污泥施用于人工种植的新疆大叶苜蓿草地，探讨了不同施用量对苜蓿生长及各元素含量的影响。研究结果表明，施用1.0-2.0kg/m^2污泥，苜蓿地上生物量显著增加，第一年增产23％－31％，第二年增产15％－31％。施用污泥苜蓿地上和地下部组织中N，P，Ca,Mg和Mn的含量总体呈增加趋势，Fe含量显著增加，而K和重金属元素Ni、Pb、As和Hg的含量与对照无显著差异，Zn和Cu的积累增多，但地上部组织中重金属元素均未超过植物中的平均含量，施用污泥未对新疆大叶苜蓿造成重金属污染。  相似文献