Extramedullary laryngeal plasmacytoma in a dog     

AI Witham  KE Hill 《New Zealand veterinary journal》2013,61(1):61-64

Abstract

CASE HISTORY:?An 8-year-old, female, spayed Border Collie presented with a 3-week history of coughing, choking and haemoptysis.

CLINICAL FINDINGS:?Inspiratory stridor was evident on clinical examination. Cervical radiographs revealed a round soft-tissue mass on the dorsal aspect of the epiglottis. A laryngeal mass was evident on examination under anaesthesia, and an incisional biopsy was obtained. Histopathology revealed a dense proliferation of neoplastic round cells morphologically consistent with plasma cell origin. Immunohistochemisty results were negative for CD3 (T cell marker) and positive for CD79a (B cell marker), resulting in a diagnosis of extramedullary plasmacytoma. The patient was treated with melphalan and prednisolone; clinical signs resolved within 1 week and the mass was no longer evident on laryngoscopy after 1 month of treatment. After 6 months of chemotherapy, the laryngeal mass recurred and euthanasia was requested. There was no evidence of systemic spread on post-mortem examination.

DIAGNOSIS:?Solitary extramedullary plasmacytoma of the canine larynx.

CLINICAL RELEVANCE:?Respiratory extramedullary plasmacytomas are extremely rare with only one laryngeal and two tracheal cases previously reported. This is the first published report of a laryngeal plasmacytoma that recurred despite combination chemotherapy with melphalan and prednisolone.  相似文献   

‘Progressive ataxia’ in a Charolais steer in New Zealand     

FI Hill  AF Julian  J Roiri 《New Zealand veterinary journal》2013,61(4)

Extract

Signs of progressive central nervous system disease in cattle aged 2 years and older should alert farmers and veterinarians to consider the possibility of bovine spongiform encephalopathy (BSE). Government veterinarians routinely assess all livestock slaughtered in meat plants in New Zealand for signs of any nervous disorder, including abnormalities of behaviour and mental state and abnormalities of posture and gait.  相似文献   

In Vitro Development of Marmoset Monkey Oocytes by Pre-antral Follicle Culture     

PL Nayudu  J Wu  HW Michelmann 《Reproduction in domestic animals》2003,38(2):90-96

A technique for in vitro maturation of oocytes from small ovarian follicles of marmoset monkeys (Callithrix jacchus) has been developed. We employed a two‐step culture system for primary follicles (45–85 μm) and a one‐step culture technique for secondary follicles (>85 μm). The two‐step technique started with the culture of stromal tissue fragments for 2 days. Thereafter, mechanically isolated follicles were transferred to a culture system where they attached to the culture surface and grew for up to a further 12 days. Significant growth of the small follicles and their oocytes was only achieved with gonadotrophins in the medium. Oocytes with a mean diameter of 39 μm from follicles <85 μm reached a mean diameter of 90 μm by the end of the two‐step culture. After in vitro maturation, 19% of oocytes from these follicles had progressed to the germinal vesicle breakdown (GVBD). Follicles between 85 and 170 μm in diameter were isolated from the stroma and placed directly in the culture. Oocytes from these follicles had a mean diameter of 64 μm. The maximum size the oocytes reached in culture was related to the age of the females (pre‐pubertal females: 102 ± 1.3 μm; adults: 96 ± 1.4 μm). Twenty‐seven per cent of oocytes from pre‐pubertal ovaries achieved GVBD and nearly two‐thirds of these progressed to polar body stage. From adult ovaries, only 12% progressed to GVBD and one‐third of these to polar body stage. It is possible to develop mature oocytes in vitro from marmoset secondary pre‐antral follicles (>85 μm). From primary follicles, although near full size oocytes were developed, maturation capacity was incomplete.  相似文献   

ASTRONOMICAL NOTES     

Hill GA 《Science (New York, N.Y.)》1892,19(484):275-276

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The variance of the variance - genetic analysis of environmental variability     

William G. Hill 《Zeitschrift für Tierzüchtung und Züchtungsbiologie》2007,124(2):49-49

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THE SACRAMENTO FOREST     

Hill RT 《Science (New York, N.Y.)》1901,14(358):739-740

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The role of catastrophic injury or sudden death of the horse in race‐day jockey falls and injuries in California, 2007–2012          下载免费PDF全文

P. L. Hitchens  A. E. Hill  S. M. Stover 《Equine veterinary journal》2016,48(1):50-56

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Prevalence,location and symmetry of noncatastrophic ligamentous suspensory apparatus lesions in California Thoroughbred racehorses,and association of these lesions with catastrophic injuries          下载免费PDF全文

A. E. Hill  I. A. Gardner  T. E. Carpenter  C. M. Lee  P. L. Hitchens  S. M. Stover 《Equine veterinary journal》2016,48(1):27-32

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Evaluating Quality and Adequacy of Gastrointestinal Samples Collected using Reusable or Disposable Forceps          下载免费PDF全文

J.A. Cartwright  T.L. Hill  S. Smith  D. Shaw 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2016,30(4):1002-1007

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Effectiveness of combined acupuncture and manual therapy relative to no treatment for canine musculoskeletal pain     

David M. Lane  Sarah A. Hill 《The Canadian veterinary journal. La revue veterinaire canadienne》2016,57(4):407-414

Despite the rise in popularity of both acupuncture and manual therapy in veterinary medicine, and the increasing number of Canadian veterinarians practising these techniques, there is little research demonstrating their effectiveness. In this repeated measures, therapeutic trial, 47 client-owned dogs with naturally occurring lameness were assessed for clinical response to treatment. Owners were blinded to the treatment schedule and completed questionnaires to assess their dogs’ comfort and mobility. Comparison between pre- and post-treatment results demonstrated that combined acupuncture and manual therapy provides immediate short-term improvement in comfort and mobility, as demonstrated by owner observed changes in play behavior (P = 0.015), walking (P < 0.001), trotting (P = 0.002), jumping (P < 0.001), descending stairs (P = 0.003), rising from a lying position (P < 0.001), and reduced stiffness after rest (P < 0.001) or following exercise (P < 0.001). Mood and attitude also improved, but did not attain statistical significance.  相似文献