Effect of pharmacological concentrations of zinc oxide with or without the inclusion of an antibacterial agent on nursery pig performance   总被引：4，自引：0，他引：4  

Hill GM  Mahan DC  Carter SD  Cromwell GL  Ewan RC  Harrold RL  Lewis AJ  Miller PS  Shurson GC  Veum TL;NCR- Committee on Swine Nutrition 《Journal of animal science》2001,79(4):934-941

A study involving nine research stations from the NCR-42 Swine Nutrition Committee used a total of 1,978 crossbred pigs to evaluate the effects of dietary ZnO concentrations with or without an antibacterial agent on postweaning pig performance. In Exp. 1, seven stations (IA, MI, MN, MO, NE, ND, and OH) evaluated the efficacy of ZnO when fed to nursery pigs at 0, 500, 1,000, 2,000, or 3,000 mg Zn/kg for a 28-d postweaning period. A randomized complete block experiment was conducted in 24 replicates using a total of 1,060 pigs. Pigs were bled at the 28-d period and plasma was analyzed for Zn and Cu. Because two stations weaned pigs at < 15 d (six replicates) and five stations at > 20 d (18 replicates) of age, the two sets of data were analyzed separately. The early-weaned pig group had greater (P < 0.05) gains, feed intakes, and gain:feed ratios for the 28-d postweaning period as dietary ZnO concentration increased. Later-weaned pigs also had increased (P < 0.01) gains and feed intakes as the dietary ZnO concentration increased. Responses for both weanling pig groups seemed to reach a plateau at 2,000 mg Zn/kg. Plasma Zn concentrations quadratically increased (P < 0.01) and plasma Cu concentrations quadratically decreased (P < 0.01) when ZnO concentrations were > 1,000 mg Zn/kg. Experiment 2 was conducted at seven stations (KY, MI, MO, NE, ND, OH, and OK) and evaluated the efficacy of an antibacterial agent (carbadox) in combination with added ZnO. The experiment was a 2 x 3 factorial arrangement in a randomized complete block design conducted in a total of 20 replicates. Carbadox was added at 0 or 55 mg/kg diet, and ZnO was added at 0, 1,500, or 3,000 mg Zn/ kg. A total of 918 pigs were weaned at an average 19.7 d of age. For the 28-d postweaning period, gains (P < 0.01), feed intakes (P < 0.05), and gain:feed ratios (P < 0.05) increased when dietary ZnO concentrations increased and when carbadox was added. These responses occurred in an additive manner. The results of these studies suggest that supplemental ZnO at 1,500 to 2,000 mg Zn/kg Zn improved postweaning pig performance, and its combination with an antibacterial agent resulted in additional performance improvements.  相似文献   

Characterisation of major and minor Dermatophagoides allergens in canine atopic dermatitis   总被引：1，自引：0，他引：1  

Nuttall TJ  Lamb JR  Hill PB 《Research in veterinary science》2001,71(1):51-57

Atopic dermatitis is a well-recognised chronic inflammatory skin disease of humans and dogs. Most atopic dogs are sensitised to Dermatophagoides mites. The aim of this study was to characterise allergens in different Dermatophagoides species using polyclonal and monoclonal antibodies to canine IgE. Western blots were prepared from crude extracts of D farinae, D pteronyssinus and D microceras, and purified group 1 and 2 allergens under reducing and non-reducing conditions. They were probed with sera from atopic (n = 33) and healthy (n = 27) dogs. There was no significant difference in the sensitivity or specificity between the polyclonal and monoclonal sera in detecting Dermatophagoides -specific IgE. Major allergens common to both D farinae and D pteronyssinus were detected at 97-98 kDa, 103-104 kDa and 134-139 kDa on both reducing and non-reducing blots. Major allergens at 84-85 kDa, 65-69 kDa and 44-45 kDa were only recognised on reducing blots, suggesting that these are fragments of the larger allergens. Only a few sera recognised group 1 or 2 allergens on blots of crude extracts or purified allergens. These results confirm that, in atopic dogs, high molecular weight allergens are the most important Dermatophagoides allergens, rather than the low molecular weight group 1 and 2 proteins.  相似文献   

Postprandial venous ammonia concentrations in the diagnosis of hepatobiliary disease in dogs     

Walker MC  Hill RC  Guilford WG  Scott KC  Jones GL  Buergelt CD 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2001,15(5):463-466

A postprandial ammonia tolerance test (PPATT) was performed on normal dogs and dogs with signs that suggested they may have liver disease. All dogs underwent transcolonic scintigraphy, liver biopsy, or both and were assigned to extrahepatic disease, primary hepatocellular, and congenital portosystemic vascular anomalies (PSVA) groups. Each dog was fed a chicken and rice diet providing 25% of its estimated daily metabolizable energy requirement (MER) as an ammonia challenge. This is practical in patients with liver disease because ammonium chloride administration often causes vomiting or ammonia toxicity. Venous ammonia concentrations were measured before feeding and every 2 hours after feeding for 8 hours. No difference in mean ammonia concentrations between dogs with extrahepatic disease and control dogs was found. Therefore, the specificity of the PPATT was 100%. Dogs with hepatocellular disease showed no change in mean ammonia concentration at any time point, before or after feeding, but sensitivity was greatest when venous ammonia was measured 6 hours after feeding (sensitivity before feeding, 28%, and after feeding, 36%). Among dogs with congenital PSVA, mean ammonia concentrations were higher than the reference range at all time points before and after feeding, and peak mean ammonia concentration occurred 6 hours after feeding. In this group, the sensitivity of the PPATT was 81% before feeding and 91% 6 hours after feeding. This study demonstrates that the measurement of venous ammonia concentration is a useful test to detect congenital PSVA, and the sensitivity of the test may be improved by sampling 6 hours after feeding. The PPATT has poor sensitivity in detecting primary hepatocellular disease.  相似文献   

The effect of cyclopiazonic acid on the development of pale, soft, and exudative pork from pigs of defined malignant hyperthermia genotype     

Byrem TM  Booren AM  Hill GM  Chu FS  Strasburg GM 《Journal of animal science》1999,77(1):166-172

Malignant hyperthermia (MH) and the mycotoxin cyclopiazonic acid (CPA) are each associated with abnormal calcium homeostasis in skeletal muscle, a key underlying factor in the development of pale, soft, and exudative (PSE) pork. To determine whether the natural presence of CPA in livestock feed ingredients contributes to the varying incidence of PSE in the pork industry, various levels of CPA (.1 to 50 mg/kg of diet) were included in the diets of market weight hogs (n = 52) of defined malignant hyperthermia genotype (NN = normal, Nn = a MH carrier, and nn = MH-positive). Animals with two copies of the MH mutation (nn) displayed improved live animal performance compared with NN and Nn animals (increased feed intake, average daily gain, and feed efficiency) but yielded lower quality loin chops as indicated by lower 45-min pH (P<.01), higher Commission Internationale de l'Eclairage (CIE) L* color coordinate values (P<.05), and higher drip losses (P<.01). The effects of CPA varied. In the first feeding trial, conducted under normal outside temperatures (2 degrees C), CPA had no effect (P> .2) on either live animal performance or meat quality. During the second trial, conducted under extreme outside temperatures (-18 degrees C), CPA-dependent reductions (P<.05) in feed intake, average daily gain, and 45-min pH in nn hogs support the possibility of interactions between malignant hyperthermia and dietary CPA on skeletal muscle calcium homeostasis and the development of PSE pork. These results suggest that this interaction may require stressful environmental conditions or the ingestion of CPA doses much higher than occur under natural conditions.  相似文献   

Plasma progesterone concentrations before mating and in early pregnancy in the beef heifer     

D M Henricks  D R Lamond  J R Hill  J F Dickey 《Journal of animal science》1971,33(2):450-454

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CLINICAL EXTRACORPOREAL OXYGENATION FOR RESPIRATORY INSUFFICIENCY     

J. Donald Hill M.D. 《Veterinary surgery : VS》1973,2(2):27-28

There is today a large group of patients who die for the simple reason that their lungs can no longer transport sufficient oxygen to meet the demands of the body. The projected number of deaths resulting from acute respiratory insufficiency in 1977, in the United States is 86,000. The average age of these patients will be 46 years.¹ This establishes a rather high priority for developing newer methods of prevention and treatment of this syndrome. Prevention is the most important facet of this syndrome and many of its contributing etiological factors will be better clarified and, subsequently, better managed in the next decade.  相似文献   

A procedure for the examination of the liver and pancreas in dogs     

J. R. F. Dalton  F. W. G. Hill 《The Journal of small animal practice》1972,13(9):527-530

A technique is described for the visual examination and biopsy sampling of the affected organ in canine liver and pancreatic dysfunction.
Résumé . On a décrit une technique pour l'examen visuel et la biopsie d'essais de l'organe affecté dans le foie du chien et le mauvais fonctionnement du pancreas.
Zusammenfassung . Man hat eine Technik beschrieben, für die Sichtprobe und die Biopsie-Probenahme des angegriffenen Organs in der Hundeleber und in der Bauchspeichelschlechtfunktion.  相似文献   

The postnatal development of intestinal disaccharidases in the calf   总被引：2，自引：0，他引：2  

F Toofanian  D E Kidder  F W Hill 《Research in veterinary science》1974,16(3):382-392

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A Histological Study of the Effects of Enzootic Abortion of Ewes Virus in the Lactating Bovine Mammary Gland   总被引：1，自引：0，他引：1       下载免费PDF全文

A. H. Corner  G. L. Bannister    D. P. Hill 《Canadian journal of veterinary research》1968,32(1):372-381

Inoculation of the udders of cows with the virus of enzootic abortion of ewes resulted in a severe acute mastitis. The mastitis was characterized clinically by pyrexia, anorexia, decreased milk production, swelling and marked alteration in the physical quality of the milk. The basic lesion was necrosis of alveolar and duct epithelial cells. Virus particles were demonstrated in all levels of the mammary gland three days after inoculation illustrating the rapid spread of the agent. Cells resembling Reed-Sternberg cells and similar to those seen in experimental mastitis produced by the virus of infectious bovine rhinotracheitis were seen in tissues collected six and nine days after inoculation.  相似文献   

Theileria-type piroplasms of Rhodesian Artiodactyla     

R R Hill  J B Condy  B A Matson 《The Veterinary record》1969,84(11):287-288

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