The impact of federal drug regulations on food animal practice.     

A D Jernigan  G F Hoffsis 《Veterinary Clinics of North America: Food Animal Practice》1991,7(3):651-658

This article discusses some of the regulations governing the use of drugs in ruminants. Because drug disposition is so influenced by dose, duration, and disease status, it is difficult to publish specific withdrawal time information. A discussion of calculation of withdrawal times is included.  相似文献   

Jejunal mucosal lactase activity from birth to 3 weeks in conventionally raised calves     

G D St Jean  D M Rings  L M Schmall  G F Hoffsis  B L Hull 《American journal of veterinary research》1989,50(9):1496-1498

The descending portion of the duodenum of 6 Holstein calves less than 24 hours old was cannulated. Sequential biopsy specimens of the proximal jejunal mucosa were obtained every other day for 3 weeks. Lactase activity in the mucosal specimens was determined and was highest at day 1, but decreased with age. Mean lactase activity was significantly (P less than 0.05) higher for days 1, 3, 5, and 7, compared with days 19 and 21.  相似文献   

The carbohydrate digestion-absorption test in the horse. Technic and normal values     

W F Loeb  L D McKenzie  G F Hoffsis 《The Cornell veterinarian》1972,62(4):524-531

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Serological survey of pre-weaned New Zealand fur seals (Arctocephalus forsteri) for brucellosis and leptospirosis     

GF Mackereth  KM Webb  JS O'Keefe  PJ Duignan  R Kittelberger 《New Zealand veterinary journal》2013,61(6):428-432

AIM: To conduct a longitudinal serological survey for evidence of Brucella spp and Leptospira spp infection of pre-weaned New Zealand fur seals in a colony on the Otago Peninsula.

METHODS: Seal pups were repeatedly captured on a monthly basis from February through to July 2001. Pups were tagged at first capture and a blood sample was taken at each capture event. A total of 163 sera were collected from 118 seal pups. Where sufficient volume was collected, the sera were tested for leptospirosis using the microscopic agglutination test (MAT), and for brucellosis using the competitive enzyme-linked immunosorbent assay (ELISA) for Brucella abortus.

RESULTS: None of 128 sera from 101 seals tested positive to the ELISA for B. abortus. All tests for Leptospira interrogans serovars Grippotyphosa, Copenhageni, Bratislava and Leptospira borgpetersenii serovar Ballum were negative at a cut-off of <1/100 dilution. Positive or suspicious titres were found to L. interrogans serovars Canicola and Pomona and L. borgpetersenii serovar Hardjo. The highest titres (12,800) were found to serovar Pomona. The titre to serovar Pomona in one seal rose from <1/50 in March to 12,800 in April and was <1/50 when re-sampled in July. The titre to serovar Pomona in another seal dropped from 12,800 in May to <1/50 in June. These seals also had titres to serovar Hardjo, which rose or fell in the same manner. All suspicious or positive titres occurred in late April and early May, when the pups were approximately 4–5 months old. In June and July, all seals tested were negative.

CONCLUSIONS: There was no serological evidence of Brucella infection in the pre-weaned fur seals at the colony. Positive titres to serovars Pomona, Hardjo, or Canicola suggest that a Leptospira species was present at the colony, however isolation or visualisation of the organism is required to confirm this. Care should be exercised when handling New Zealand fur seals to prevent human infection or inadvertent transfer of leptospirosis to another marine mammal species.  相似文献   

Idiopathic immune-mediated hemolytic anemia in a calf.     

C K Fenger  G F Hoffsis  G J Kociba 《Journal of the American Veterinary Medical Association》1992,201(1):97-99

Severe anemia was found in a 4-month-old heifer, which was admitted with a 1-day history of anorexia, signs of depression, and recumbency. A diagnosis of immune-mediated hemolytic anemia (IHA) was made on the basis of a Coomb's titer of 1:128 and decreased resistance to osmotic stress, as determined by an RBC fragility test. Anaplasmosis and leptospirosis were ruled out as possible causes of the IHA. Other causes of hemolytic anemia, including intoxication by copper, water, Brassica spp, or drugs were ruled out. Therefore the IHA was considered idiopathic. Treatment consisted of supportive therapy, oxytetracycline, and dexamethasone. After 60 days of treatment, CBC, Coomb's test result, and RBC fragility were within normal limits.  相似文献   

Prognostic value of surgical and postoperative findings in cattle with abomasal volvulus.     

P D Constable  G St Jean  B L Hull  D M Rings  G F Hoffsis 《Journal of the American Veterinary Medical Association》1991,199(7):892-898

A prospective study evaluating the prognostic value of surgical and postoperative findings in 80 cattle with abomasal volvulus was performed. Surgical correction of abomasal volvulus was performed in all animals. After surgery, cattle were categorized into 3 groups: productive (acceptable milk production or appetite, n = 59), salvaged (poor milk production or appetite, n = 10), and nonsurvivors (n = 11). Cattle with omasal-abomasal volvulus had a significantly (P less than 0.005) worse prognosis than cattle without omasal involvement. Large abomasal fluid volume, venous thrombosis, and blue or black abomasal color before decompression were all indicative of a poor prognosis. Most cattle had poor or fair appetites the first day after surgery; productive animals had marked improvement in appetite over the next 3 days. All cattle observed to have a good appetite within 3 days after surgery were later determined to be productive animals. The heart rate decreased in all groups after surgery; however, tachycardia (heart rate greater than 80 beats/min) was sustained in cattle that were later salvaged for slaughter. Diarrhea was observed after surgery in 54% of cattle. The duration of diarrhea was significantly shorter (P = 0.009) in productive cattle than in salvaged and nonsurviving cattle. The presence or absence of diarrhea was only of predictive value when considered in conjunction with the estimated abomasal fluid volume.  相似文献   

Isolation of Mycobacterium paratuberculosis from washed bovine ova after in vitro exposure     

R F Rohde  W P Shulaw  W D Hueston  S Bech-Nielsen  G K Haibel  G F Hoffsis 《American journal of veterinary research》1990,51(5):708-710

To establish whether Mycobacterium paratuberculosis could be cultured from Dulbecco phosphate-buffered saline solution (DPBSS) and to test 3 sampling methods, DPBSS supplemented with 2% fetal bovine serum was inoculated with M paratuberculosis at concentrations of 10(4), 10(3), 10(2), 10(1), and 10(0) colony-forming units/ml. The inoculated media was sampled after mixing, after centrifugation, and after centrifugation and decontamination with 0.75% hexadecylpyridinium chloride. The samples were inoculated onto 3 slants of Herrolds egg yolk medium supplemented with sodium pyruvate and mycobactin J and 1 slant without mycobactin J. Mycobacterium paratuberculosis was isolated following all 3 sampling methods for all concentrations. Treatment with hexadecylpyridinium chloride decreased the number of colonies isolated. To test the efficacy of a 10-step wash procedure for removing M paratuberculosis from bovine ova, washed zona pellucida intact bovine ova were incubated in DPBSS supplemented with 2% fetal bovine serum containing concentrations of 10(4), 10(3), 10(2), 10(1), and 10(0) colony-forming units of M paratuberculosis/ml for 12 hours at 22 C. Ten zona pellucida intact ova were removed from each concentration and washed by passing through 10 changes of DPBSS supplemented with 15% fetal bovine serum. The media from each wash step was inoculated onto slants of Herrolds egg yolk medium. The ova were included with the tenth wash step. Mycobacterium paratuberculosis was isolated from 1 of 10 tenth-wash steps at the 10(4) concentration and 5 of 10 tenth-wash steps at 10(3).  相似文献   

Leiomyoma of the uterus of a mare          下载免费PDF全文

Hoffsis GF  Davis GW  Saint-Jean G 《The Canadian veterinary journal. La revue veterinaire canadienne》1986,27(9):319-320

A mare was presented for diagnosis and treatment of infertility of three seasons duration. Examination revealed a uterine tumor. The tumor was removed surgically and diagnosed histopathologically as a leiomyoma. The mare conceived and successfully foaled after the surgery.  相似文献   

First detection of bovine noroviruses and detection of bovine coronavirus in Australian dairy cattle          下载免费PDF全文

SJ Symes  JL Allen  PD Mansell  KL Woodward  KE Bailey  JR Gilkerson  GF Browning 《Australian veterinary journal》2018,96(6):203-208

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Survey of veterinary prescribing for poultry disease     

HK Crabb  LY Hardefeldt  KE Bailey  H Billman‐Jacobe  JR Gilkerson  GF Browning 《Australian veterinary journal》2019,97(8):288-288

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