The use of the standard exercise test to establish the clinical significance of mild echocardiographic changes in a Thoroughbred poor performer     

Meyer C  Gerber R  Guthrie AJ 《Journal of the South African Veterinary Association》2004,75(2):100-102

A 4-year-old Thoroughbred gelding racehorse was referred to the Onderstepoort Veterinary Academic Hospital (OVAH) with a history of post-race distress and collapse. In the absence of any obvious abnormalities in the preceding diagnostic work-up, a standard exercise test was performed to determine an underlying cause for the post-race distress reported. In this particular case oxygen desaturation became evident at speeds as slow as 6 m/s, where PO2 was measured at 82.3 mm Hg. Similarly at a blood pH of 7.28, PCO2 had dropped to 30.0 mm Hg indicating a combined metabolic acidosis and respiratory alkalosis. The cause of the distress was attributed to a severe hypoxia, with an associated hypocapnoea, confirmed on blood gas analyses, where PO2 levels obtained were as low as 56.6 mm Hg with a mean PCO2 level of 25.4 mm Hg during strenuous exercise. Arterial oxygenation returned to normal immediately after cessation of exercise to 106.44 mm Hg, while the hypocapnoeic alkalosis, PCO2 25.67 mm Hg, persisted until the animal's breathing normalized. The results obtained were indicative of a dynamic cardiac insufficiency present during exercise. The combination of an aortic stenosis and a mitral valve insufficiency may have resulted in a condition similar to that described as high-altitude pulmonary oedema, with respiratory changes and compensation as for acute altitude disease. The results obtained were indicative of a dynamic cardiac insufficiency present during exercise and substantiate the fact that an extensive diagnostic regime may be required to establish a cause for poor performance and that the standard exercise test remains an integral part of this work-up.  相似文献   

Verteilung und Aktivitäten oxydativer Enzyme in den apokrinen Hautdrüsen des Schweines*     

W. Meyer  K. Neurand 《Anatomia, histologia, embryologia》1976,5(2):189-192

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Poloxalene for treatment of cattle with alfalfa bloat     

E E Bartley  D A Stiles  R M Meyer  S F Scheidy  J G Clark  F W Boren 《Journal of the American Veterinary Medical Association》1967,151(3):339-343

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Effect of the magnesium concentration in blood on the phagocytic activity of blood phagocytes     

R Leirer  H Meyer  G Steinbach 《Archiv fuer experimentelle veterinaermedizin》1969,23(5):1021-1025

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Brucella organisms isolated from dogs: comparison of characteristics of members of the genus Brucella   总被引：3，自引：0，他引：3  

M E Meyer 《American journal of veterinary research》1969,30(10):1751-1756

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Effects of Storing Pig Ovaries at 4 or 20°C for Different Periods of Time on the Morphology and Viability of Pre-Antral Follicles     

CM Lucci  LL Schreier  GM Machado  CA Amorim  SN Báo  JR Dobrinsky 《Reproduction in domestic animals》2007,42(1):76-82

The purpose of this study was to evaluate the effect of cooling ovarian tissue on pig pre-antral follicles. Ovaries were maintained in saline solution (0.9%) at 4 or 20 degrees C for 6, 12 or 18 h. After storage, pre-antral follicles were morphologically evaluated. While primordial follicles were not affected by the storage, the percentage of morphologically normal growing follicles was significantly reduced in ovarian tissue stored at 20 degrees C for 12 or 18 h. To test the viability of stored follicles, growing follicles isolated from ovaries stored at 4 degrees C for 18 h and at 20 degrees C for 6 h were cultured for 3 days. Follicles stored in either condition presented the same growth pattern in vitro as fresh follicles. We conclude that storage of pig ovaries at 4 degrees C for up to 18 h or at 20 degrees C for up to 6 h does not affect the morphology of growing follicles or their ability to grow in vitro.  相似文献   

The effect of anesthesia and surgery on heart rate variability in dogs     

HL Shafford  JR Dodam  AW Spier 《Veterinary anaesthesia and analgesia》2005,32(4):7-7

Heart rate variability (HRV) may be useful for objective assessment of stress and pain in animals. The objective of this study was to describe the effect of anesthesia and surgery on HRV in dogs. We hypothesized that surgery would decrease HRV to a greater degree and for a longer duration than anesthesia alone. Four healthy male dogs (29 ± 2 kg) were instrumented for ambulatory ECG monitoring. Continuous ECG data was obtained for 1 day prior to, and 6 days following anesthesia alone (ANES) or anesthesia plus unilateral stifle arthrotomy (ANSX). The anesthetic protocol included xylazine (0.5 mg kg^–1 IM), morphine (0.5 mg kg^–1 IM), atropine (0.04 mg kg^–1 IM), thiopental (10 mg kg^–1 IV) and isoflurane in oxygen. A single dose of morphine (0.5 mg kg^–1 IM) was administered at extubation. Time domain analysis of HRV was performed on 5 minutes epochs of artefact‐ and arrhythmia‐free ECG data obtained at 12 noon and 12 midnight on each of the seven experimental days. Mean RR interval, standard deviation of normal R‐R intervals (SDNN), and the standard deviation of successive differences in RR intervals (SDSD) were compared to baseline for ANES and ANSX. Pain scores obtained during the day were also evaluated. Significance was set at p < 0.01. There were no differences between groups for any baseline data. Mean RR interval did not differ from baseline on days 1–6 in ANES or ANSX. SDNN and SDSD values at noon were not different from baseline on days 1–6 in ANES or ANSX. At midnight on days 1 and 2, SDNN was significantly decreased from baseline in ANSX, and on day 1 a significant difference between groups existed. ANSX values of SDSD at midnight were significantly decreased from baseline and ANES on day 1. Pain scores for ANSX were significantly greater than baseline on days 1–3, and different from ANES on days 1–5. These results suggest that HRV is decreased following anesthesia plus surgery, and that changes in HRV may be associated with pain.  相似文献   

Estimates of covariance functions for growth of Nelore cattle applying a parametric correlation structure to model within-animal correlations     

L.G. Albuquerque  K. Meyer 《Livestock Production Science》2005,93(3):213-222

A total of 20,065 weights recorded on 3016 Nelore animals were used to estimate covariance functions for growth from birth to 630 days of age, assuming a parametric correlation structure to model within-animal correlations. The model of analysis included fixed effects of contemporary groups and age of dam as quadratic covariable. Mean trends were taken into account by a cubic regression on orthogonal polynomials of animal age. Genetic effects of the animal and its dam and maternal permanent environmental effects were modelled by random regressions on Legendre polynomials of age at recording. Changes in direct permanent environmental effect variances were modelled by a polynomial variance function, together with a parametric correlation function to account for correlations between ages. Stationary and nonstationary models were used to model within-animal correlations between different ages. Residual variances were considered homogeneous or heterogeneous, with changes modelled by a step or polynomial function of age at recording. Based on Bayesian information criterion, a model with a cubic variance function combined with a nonstationary correlation function for permanent environmental effects, with 49 parameters to be estimated, fitted best. Modelling within-animal correlations through a parametric correlation structure can describe the variation pattern adequately. Moreover, the number of parameters to be estimated can be decreased substantially compared to a model fitting random regression on Legendre polynomial of age.  相似文献   

In vitro fertilization of porcine tubal ova     

J N Meyer  D Smidt 《Berliner und Münchener tier?rztliche Wochenschrift》1973,86(7):121-125

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Net energy requirements for growth of lambs age three to five months     

P V Rattray  W N Garrett  H H Meyer  G E Bradford  N Hinman  N E East 《Journal of animal science》1973,37(6):1386-1389

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