The lipid compositions of two isolates of Cladosporium cucumerinum do not explain their differences in sensitivity to fungicides which inhibit sterol biosynthesis     

Geoffrey A. Carter  Sheila J. Kendall  Raymond S. Burden  Carolyn S. James  Terence Clark 《Pest management science》1989,26(2):181-192

Isolate 840905 of Cladosporium cucumerinum, when grown on agar or in liqiud medium, was sensitive to triadimenol, HWG 1608 (tebuconazole), fenpropimorph and pimaricin but relatively resistant to terbinafine. Conversely, isolate 49628 was sensitive to terbinafine but relatively resistant to the other fungicides. Changes in sterol composition following treatment with the fungicides reflected the known modes of action of each fungicide. When individual enantiomers of triadimenol were tested against isolate 840905 the order of activity in reducing mycelial growth was 1 S, 2R > 1R, 2R > 1R, 2S ≈? 1S, 2S, and this was paralleled by the depletion of ergosterol and the appearance of 14α-methyl sterols. Isolate 49628 had a greater saturated:unsaturated fatty acid ratio than did isolate 840905 but no major changes in fatty acid composition of either isolate were induced by fungicide treatment. There appears to be no obvious explanation for the differences in fungicide sensitivity of the isolates in terms of their lipid compositions.  相似文献   

What is your diagnosis? Salter-Harris type I fracture of the distal humeral physis     

Clark B  Wilkens BE 《Journal of the American Veterinary Medical Association》2001,218(1):17-18

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Spongiotic vesicular dermatitis as a cutaneous reaction pattern in seven horses     

Hargis AM  Clark EG  Duclos DD  Leclerc S  West K 《Veterinary dermatology》2001,12(5):291-296

Over a 6-year period seven adult horses of different breeds and genders developed multifocal, exudative, oozing dermatitis characterized histologically by epidermal spongiotic vesicles and perivascular eosinophilic, neutrophilic and mixed mononuclear inflammation. Three horses were pruritic. Systemic disease was not noted. Two horses had a history of recurrent urticaria (hives) and one horse had nodules or welt-type lesions that progressed to exudative, oozing lesions. Interepithelial immunoglobulin (Ig)G was detected by avidin-biotin complex-peroxidase staining, but the pattern of staining was more consistent with epithelial oedema than specific IgG deposition associated with pemphigus. The exudative oozing lesions developed under circumstances suggesting that dermal oedema progressed to intracellular and intercellular epidermal oedema, which in turn progressed to the spongiotic vesicular epidermal lesions.  相似文献   

Metal chelate molluscicides: The redistribution of iron diazaalkanolates from the gut lumen of the slug,Deroceras reticulatum (Müller) (Pulmonata: Limacidae)     

Suzanne J. Clark  Nicola P. Coward  Glenn W. Dawson  Ian F. Henderson  Andrew P. Martin 《Pest management science》1995,44(4):381-388

Two related iron chelates, one toxic to slugs by ingestion, the other not, were introduced into the foregut of D. reticulatum. The subsequent movement and redistribution of the metal within the slug tissues was studied by labelling the chelates with the radioactive isotope ⁵⁵Fe. In slugs which survived treatment approximately half of the ⁵⁵Fe was voided in faeces. The iron retained became unevenly distributed, the highest concentration occurring in the digestive gland, irrespective of the chelate used. At high doses, slugs treated with tris(1-oxo-1,2-diazabutan-2-oxido)Fe(III) were fatally poisoned while those treated with the homologue, tris(1-oxo-1,2-diazaoctan-2-oxido)Fe(III) were not. Slugs killed by the toxic chelate consistently contained proportionally less iron in the digestive gland and proportionally more in the body wall and reproductive system. Dosing slugs already killed by carbon dioxide asphyxiation gave a similar pattern, suggesting that the greater mobility of the iron from the toxic chelate was not a function of the slugs' metabolism.  相似文献   

Highly visible, curiously intangible     

Clark GA 《Science (New York, N.Y.)》1999,283(5410):2029, 2031-2029, 2032

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Poloxalene as an Anti-Bloat Compound and Its Effect on Milk Yield and Composition   总被引：1，自引：0，他引：1       下载免费PDF全文

L. M. Bezeau  R. D. Clark    R. J. Gray 《Canadian journal of veterinary research》1967,31(12):352-353

Poloxalene, a nonionic surfactant, was fed to beef cattle on a legume ration or a high grain ration to observe its effect on bloat. It was also fed to lactating dairy cows to note any effect on yield or composition of milk.

Poloxalene was beneficial in the prevention of bloat with both legume and grain rations. It had no effect on per cent fat, protein, solids-not-fat, or yield of milk.

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Experimental ovine listeriosis. 3. Inoculation of rams     

R E Smith  I M Reynolds  G W Clark 《The Cornell veterinarian》1968,58(3):480-486

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Experimental acute toxicity of orally administered sodium selenite in lambs     

C Caravaggi  F L Clark  A R Jackson 《Research in veterinary science》1970,11(5):501-502

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Equine Protozoal Myeloencephalitis: A Report of Two Cases From Western Canada   总被引：1，自引：1，他引：0       下载免费PDF全文

E. G. Clark  H. G. G. Townsend    N. T. McKenzie 《The Canadian veterinary journal. La revue veterinaire canadienne》1981,22(5):140-144

Two cases of nonsuppurative myeloencephalitis are reported which clinically and pathologically resemble equine protozoal myeloencephalitis. Lesions in both horses were associated with Toxoplasma-like organisms visible in microscopic sections. Clinical signs and lesions in one case primarily involved the brain and in the other case principally involved the spinal cord and associated meninges. Positive identification of the organisms was not achieved; however, the etiological agent is unlikely to be a species of Toxoplasma. Recently published studies suggest a species of Sarcocystis is involved.  相似文献   

Serum protein electrophoresis and serum transaminase activity of dogs with canine distemper     

L M Snow  M J Burns  C H Clark 《American journal of veterinary research》1966,27(116):70-73

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