Review of human rabies cases in the UK and in Germany     

Johnson N  Brookes SM  Fooks AR  Ross RS 《The Veterinary record》2005,157(22):715

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Animal behavior case of the month. Two dogs were evaluated for episodic bouts of bizarre behavior     

Dodman NH  Cottam N 《Journal of the American Veterinary Medical Association》2004,225(9):1339-1341

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Isolation and identification of select oligosaccharides from commercially produced total invert sugar with a proposed mechanism for their formation     

Thavarajah P  Low NH 《Journal of agricultural and food chemistry》2006,54(7):2754-2760

Three disaccharides were isolated and purified from a commercial total invert sugar (TIS). The structures of these compounds were determined by a combination of acid and enzymatic hydrolysis studies, chromatographic comparison to standards, and nuclear magnetic resonance spectroscopy. These carbohydrates were identified as O-alpha-D-glucopyranosyl-(1-->3)-D-fructose (IS1), O-beta-D-fructofuranosyl-(2-->6)-D-glucose (IS2), and O-alpha-D-glucopyranosyl-beta-D-glucopyranoside (IS3). On the basis of these structures a mechanism for the hydrochloric acid catalyzed hydrolysis of sucrose is proposed: protonation of the glycosidic oxygen of sucrose leading to the formation of glucopyranosyl and fructofuranosyl oxonium ions of D-glucose or D-fructose, respectively, followed by nucleophilic attack of these ions by D-glucose or D-fructose at either the alpha- or beta-face.  相似文献   

Apes save tools for future use     

Mulcahy NJ  Call J 《Science (New York, N.Y.)》2006,312(5776):1038-1040

Planning for future needs, not just current ones, is one of the most formidable human cognitive achievements. Whether this skill is a uniquely human adaptation is a controversial issue. In a study we conducted, bonobos and orangutans selected, transported, and saved appropriate tools above baseline levels to use them 1 hour later (experiment 1). Experiment 2 extended these results to a 14-hour delay between collecting and using the tools. Experiment 3 showed that seeing the apparatus during tool selection was not necessary to succeed. These findings suggest that the precursor skills for planning for the future evolved in great apes before 14 million years ago, when all extant great ape species shared a common ancestor.  相似文献   

Drilling to gabbro in intact ocean crust     

Wilson DS  Teagle DA  Alt JC  Banerjee NR  Umino S  Miyashita S  Acton GD  Anma R  Barr SR  Belghoul A  Carlut J  Christie DM  Coggon RM  Cooper KM  Cordier C  Crispini L  Durand SR  Einaudi F  Galli L  Gao Y  Geldmacher J  Gilbert LA  Hayman NW  Herrero-Bervera E  Hirano N  Holter S  Ingle S  Jiang S  Kalberkamp U  Kerneklian M  Koepke J  Laverne C  Vasquez HL  Maclennan J  Morgan S  Neo N  Nichols HJ  Park SH  Reichow MK  Sakuyama T  Sano T  Sandwell R  Scheibner B  Smith-Duque CE  Swift SA  Tartarotti P  Tikku AA  Tominaga M  Veloso EA 《Science (New York, N.Y.)》2006,312(5776):1016-1020

Sampling an intact sequence of oceanic crust through lavas, dikes, and gabbros is necessary to advance the understanding of the formation and evolution of crust formed at mid-ocean ridges, but it has been an elusive goal of scientific ocean drilling for decades. Recent drilling in the eastern Pacific Ocean in Hole 1256D reached gabbro within seismic layer 2, 1157 meters into crust formed at a superfast spreading rate. The gabbros are the crystallized melt lenses that formed beneath a mid-ocean ridge. The depth at which gabbro was reached confirms predictions extrapolated from seismic experiments at modern mid-ocean ridges: Melt lenses occur at shallower depths at faster spreading rates. The gabbros intrude metamorphosed sheeted dikes and have compositions similar to the overlying lavas, precluding formation of the cumulate lower oceanic crust from melt lenses so far penetrated by Hole 1256D.  相似文献   

Fish population and behavior revealed by instantaneous continental shelf-scale imaging     

Makris NC  Ratilal P  Symonds DT  Jagannathan S  Lee S  Nero RW 《Science (New York, N.Y.)》2006,311(5761):660-663

Until now, continental shelf environments have been monitored with highly localized line-transect methods from slow-moving research vessels. These methods significantly undersample fish populations in time and space, leaving an incomplete and ambiguous record of abundance and behavior. We show that fish populations in continental shelf environments can be instantaneously imaged over thousands of square kilometers and continuously monitored by a remote sensing technique in which the ocean acts as an acoustic waveguide. The technique has revealed the instantaneous horizontal structural characteristics and volatile short-term behavior of very large fish shoals, containing tens of millions of fish and stretching for many kilometers.  相似文献   

Identification of new morphological and life-cycle stages of Cochlosoma anatis and experimental transmission using pseudocyst     

Evans NP  Evans RD  Fitz-Coy S  Pierson FW  Robertson JL  Lindsay DS 《Avian diseases》2006,50(1):22-27

Cochlosoma anatis is a flagellated intestinal parasite that infects a variety of avian species. C. anatis infections have been associated with decreased weight gain and increased morbidity and mortality. Conditions favoring the growth of this organism in birds are current pathogenic intestinal infections and/or young age. There is little data describing the life cycle of this parasite. In this study, electron microscopy images are presented that document longitudinal binary fission of the trophozoite stage and outline the events of pseudocyst formation, which includes a rounding stage. Evidence provided here indicates that the pseudocyst stage may be a mechanism for transmission of this organism. The observations reported here provide additional evidence of homology between Cochlosoma and members of the trichomonad order.  相似文献   

Adulteration of apple with pear juice: emphasis on major carbohydrates, proline, and arbutin     

Thavarajah P  Low NH 《Journal of agricultural and food chemistry》2006,54(13):4861-4867

Detection of juice-to-juice adulteration based on chemical composition studies is a common method used by government regulatory agencies and food companies. This study investigated the use of major carbohydrate (fructose, glucose and sucrose), polyol (sorbitol), proline, and phenolic profiles as indicators of pear adulteration of apple juice (PAAJ). For this work, a total of 105 authentic apple juice samples from 13 countries and 27 authentic pear juice samples from 5 countries were analyzed. Because the major carbohydrate ranges for these juices showed significant overlap their use as markers for PAAJ detection would be very limited. It was found that sorbitol and proline means for apple and pear were significantly different; however, their broad natural ranges would afford PAAJ at levels up to 30% without detection. In addition, careful selection of the pear juice used as the adulterant would further limit the usefulness of these markers for PAAJ detection. Arbutin was conclusively identified as a marker for pear juice on the basis of its presence in all 27 authentic pear samples and its absence (<0.5 microg/mL) in all 105 apple juice samples analyzed in this study. The application of the developed HPLC-PDA method for arbutin analysis to detect PAAJ at levels as low as 2% (v/v) was demonstrated. A confirmation method for the presence of arbutin in pure pear juice and apple adulterated with pear juice was introduced on the basis of the hydrolysis of arbutin to hydroquinone employing beta-glucosidase, with reactant and product monitoring by HPLC-PDA.  相似文献   

New strategies for the elimination of polio from India     

Grassly NC  Fraser C  Wenger J  Deshpande JM  Sutter RW  Heymann DL  Aylward RB 《Science (New York, N.Y.)》2006,314(5802):1150-1153

The feasibility of global polio eradication is being questioned as a result of continued transmission in a few localities that act as sources for outbreaks elsewhere. Perhaps the greatest challenge is in India, where transmission has persisted in Uttar Pradesh and Bihar despite high coverage with multiple doses of vaccine. We estimate key parameters governing the seasonal epidemics in these areas and show that high population density and poor sanitation cause persistence by not only facilitating transmission of poliovirus but also severely compromising the efficacy of the trivalent vaccine. We analyze strategies to counteract this and show that switching to monovalent vaccine may finally interrupt virus transmission.  相似文献   

Triple-bond reactivity of diphosphorus molecules     

Piro NA  Figueroa JS  McKellar JT  Cummins CC 《Science (New York, N.Y.)》2006,313(5791):1276-1279

We report a mild method for generating the diphosphorus molecule or its synthetic equivalent in homogeneous solution; the P2 allotrope of the element phosphorus is normally obtained only under extreme conditions (for example, from P4 at 1100 kelvin). Diphosphorus is extruded from a niobium complex designed for this purpose and can be trapped efficiently by two equivalents of an organic diene to produce an organodiphosphorus compound. Diphosphorus stabilized by coordination to tungsten pentacarbonyl can be generated similarly at 25 degrees C, and in this stabilized form it still efficiently consumes two organic diene molecules for every diphosphorus unit.  相似文献