Hemostatic and Fibrinolytic Indices in Neonatal Foals with Presumed Septicemia   总被引：4，自引：0，他引：4  

Michelle Henry Barton  Debra Deem Morris  Natalie Norton  Keith W. Prasse 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》1998,12(1):26-35

Thirteen coagulation tests evaluating hemostatic and fibrinolytic indices and serum cytokine and plasma endotoxin concentrations were obtained in 34 foals with a positive sepsis score (septic group) and 46 age-matched healthy foals. Compared to healthy foals, the prothrombin, activated partial thromboplastin, and whole blood recalcification times were significantly longer in septic foals. The fibrinogen and fibrin degradation products concentrations, percent plasminogen, alpha-2 antiplasmin, and plasminogen activator inhibitor activities, and tumor necrosis factor and interleukin-6 activities were greater in septic foals. Protein C antigen and antithrombin III activity were significantly lower in septic foals. Blood cultures were positive for growth and endotoxin was detected in 19 of 29 and 15 of 30 septic foals, respectively. In septicemic foals with detectable endotoxin in the plasma, the prothrombin and activated partial thromboplastin times were significantly longer and the plasminogen and antithrombin III activities were significantly less than in septic foals in which endotoxin was not detected. Twenty-three of the 34 septic foals did not survive. Septic foals that did not survive were most likely to have a positive blood culture in which a gram-negative organism was isolated. Histopathologic evidence of hemorrhage was evident in 11 foals at postmortem examination and thrombosis was identified in 2 foals. The prothrombin time was significantly longer in foals that had multisite hemorrhage at postmortem examination. The results of this study indicate that clinically relevant alternations in hemostatic and fibrinolytic indices occur in neonatal foals with septicemia and that derangements can be correlated with the presence of endotoxin in plasma. Derangements in hemostatic or fibrinolytic indices were helpful in identification of septic foals with increased risk of coagulopathy, but were not helpful in predicting hemorrhage as compared to thrombus formation. Survival of septicemic foals was correlated with gram-negative bacteremia, but not with the presence of endotoxin or coagulopathy.  相似文献   

Interaction ofpra tylenchus scribneri and helminthosporium pedicellatum in the etiology of corn root rot     

OLufunke A. Egunjobi  D. C. Norton  C. Martinson 《Phytoparasitica》1986,14(4):287-295

In experiments with both sterile and non-sterile natural soil,Pratylenchus scribneri interacted, perhaps synergistically, withHelminthosporium pedicellatum Henry (Trichometasphaeria pedicellatum Nelson) to enhance the fungus’ invasion of corn roots, with a subsequent increase in severity of root rot disease and a decline in productivity. Water stress appeared to influence the response of the corn plant to the root rot disease rather than the disease development.  相似文献   

The coccidial population in clinically normal sheep     

D D Pout  D C Ostler  L P Joyner  C C Norton 《The Veterinary record》1966,78(13):455-460

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The drug sensitivity of recently isolated strains of Eimeria meleagrimitis and a laboratory strain of Eimeria adenoeides in turkeys to robenidene     

L P Joyner  C C Norton 《Research in veterinary science》1972,13(3):279-281

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Neuronal soma and whole neuroglia of rat brain: a new isolation technique     

Norton WT  Poduslo SE 《Science (New York, N.Y.)》1971,174(4015):1221

In the report "Neuronal Soma and Whole Neuroglia of Rat Brain: A New Isolation Technique" by W. T. Norton and S. E. Podulso [167, 1144 (1970)], sentence 2, paragraph 3, column 1, p. 1144, should read: "The brains are trimmed of cerebellum and chopped fine (approximately 1 mm(3)) in an ice-cold medium consisting of 5 percent glucose, 5 percent fructose, and 1 percent bovine serum albumin (14) in 10 mM KH(2)PO(4)-NaOH buffer (pH 6.0)."  相似文献   

Monte Carlo studies of selection and inbreeding in swine. 3. Gene frequency     

B Bereskin  C E Shelby  L N Hazel  H W Norton 《Journal of animal science》1970,31(5):828-836

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Short-term ovarian responses to some pituitary hormones infused in vivo in pigs and sheep     

B Cook  C C Kaltenbach  G D Niswender  H W Norton  A V Nalbandov 《Journal of animal science》1969,29(5):711-718

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Milk production in lactating sows and time lengths used in evaluating milk production estimates     

D C Mahan  D E Becker  H W Norton  A H Jensen 《Journal of animal science》1971,33(1):35-37

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The freeze preservation of coccidia   总被引：1，自引：0，他引：1  

C C Norton  L P Joyner 《Research in veterinary science》1968,9(6):598-600

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Response of pregnant rats to sources of dietary nitrogen and cold exposure     

J L Cox  B G Harmon  D E Becker  H W Norton  A H Jensen 《Journal of animal science》1968,27(6):1567-1571

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