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101.
102.
Pierre Berard Ping Yang Hidefumi Yamauchi Kenji Umemura Shuichi Kawai 《Journal of Wood Science》2011,57(2):100-106
The use of low-grade logs to build spirally wound laminated veneer lumber (LVL) has been studied and improved from the point
of view of the gluing process, fiber orientation angle, and end joint of the LVL. The butt joint appears to be the fracture
point when the column is submitted to a compressive or bending load. Owing to the complexity of cylindrical LVL, we used a
finite element method to simulate the mechanical behavior of part of its wall. This part was small enough to be considered
flat but was representative of the structure, especially in the area of the butt joint. This allowed us to test the validity
of different settings of the parameters involved in the manufacturing process. To feed data for this model, we used the results
established for the linear and nonlinear behavior of raw hinoki in Part I of this series of articles. We then used this numerical
model to improve the quality of the butt joint by testing different settings of the joint. We show that reducing the butt
joint gap under 0.5 mm, which requires only a few changes in the production line, provides an important increase in the modulus
of upture and nonnegligible improvement of the modulus of elasticity compared to that for a ≥ 1 mm butt joint gap. 相似文献
103.
Pierre Berard Ping Yang Hidefumi Yamauchi Kenji Umemura Shuichi Kawai 《Journal of Wood Science》2011,57(2):107-113
The use of low-grade logs to build spirally wound laminated veneer lumber (LVL) has been studied and improved from the point of view of the gluing process, fiber orientation angle, and end joint of the LVL. The butt joint appears to be the fracture point when the column is submitted to a compressive or bending load. Owing to the complexity of cylindrical LVL, we used a finite element method to simulate the mechanical behavior of part of its wall. This part was small enough to be considered flat but was representative of the structure, especially in the area of the butt joint. This allowed us to test the validity of different settings of the parameters involved in the manufacturing process. To feed data for this model, we used the results established for the linear and nonlinear behavior of raw hinoki in Part I of this series of articles. We then used this numerical model to improve the quality of the butt joint by testing different settings of the joint. We show that reducing the butt joint gap under 0.5 mm, which requires only a few changes in the production line, provides an important increase in the modulus of upture and nonnegligible improvement of the modulus of elasticity compared to that for a ≥ 1 mm butt joint gap. 相似文献
104.
Response of plasma bone markers to a single intramuscular administration of calcitriol in dairy cows
Danil Kim Norio Yamagishi Izumi Abe Bhuminand Devkota Norimoto Okura Shuichi Ohashi 《Research in veterinary science》2011,90(1):124-126
To elucidate the effects of an exogenous calcitriol (1,25-dihydroxyvitamin D3) on plasma bone markers, the formation item osteocalcin (OC), undercarboxylated OC (ucOC) and bone-specific alkaline phosphatase (BALP), and the resorption parameter tartrate-resistant acid phosphatase isoform 5b (TRAP5b) and hydroxyproline (HYP) were measured in conjunction with plasma calcitriol and calcium (Ca) concentrations in dairy cows receiving calcitriol or its vehicle according to a 2 × 2 crossover design. Calcitriol (0.5 μg/kg, i.m.) increased significantly its plasma level during 6 h to day 2 and plasma Ca concentration during 12 h to day 7 compared to the vehicle. Also, plasma OC and ucOC started to rise from day 3 and 1, respectively, and remained elevated until day 7. No change in plasma BALP, TRAP5b or HYP associated with calcitriol treatment was noted. These results demonstrate that exogenous calcitriol stimulates osteoblasts to biosynthesise OC, a determinant of the bone formation in cows. 相似文献
105.
Kimura S Sasase T Ohta T Matsushita M 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2011,73(8):1025-1029
The Spontaneously Diabetic Torii-Lepr(fa) (SDT- fa/fa) rat is a new model of obese type 2 diabetes. The female SDT-fa/fa rat shows obesity, hyperglycemia and hyperlipidemia from a young age. However, it is not known whether diabetes and estrogen deficiency can lead to bone abnormalities in the female SDT-fa/fa rat. The objective of the present study was to investigate the effects of ovariectomy (OVX) on bone metabolism and bone mineral density (BMD) in the female SDT-fa/fa rat. Female Sprague-Dawley rats were used as control animals. The BMDs of the whole tibia and fifth lumbar (L5) vertebral body were analyzed at 30 weeks after OVX. Serum osteocalcin, a bone formation marker, and urine deoxypyridinoline (DPD), a bone resorption marker, were sequentially analyzed before and at 5, 15 and 30 weeks after OVX. Serum osteocalcin and urine DPD levels were lower in SDT-fa/fa rats than in control rats before OVX. Both serum osteocalcin and urine DPD levels were elevated in control rats 5-30 weeks after OVX, but only the urine DPD levels were elevated in SDT-fa/fa rats 5-30 weeks after OVX. SDT-fa/fa rats showed a decrease in the BMDs of the whole tibia and L5 vertebral body compared with control rats. OVX decreased the BMDs of the whole tibia and L5 vertebral body in control rats, but not in SDT-fa/fa rats. These data suggest that estrogen deficiency is not a risk factor for bone loss in type 2 diabetes mellitus. 相似文献
106.
ABSTRACT: To clarify the total phosphorus (P) and nitrogen (N) loading from carp culture, five commercial diets were selected from a major location in Japan, Lake Kasumigaura, for a 12-week feeding trial. These diets were prepared as per the 'Kasumigaura Feed Standard' (crude protein < 35% and digestible energy > 3.5kcal/g), and total P ranged from 1.4% to 2.0%. However, for most of the diets the P available was lower than the requirement level. A control diet was formulated with 25% fishmeal to comply with that standard and contain adequate available P. Duplicate groups of juvenile carp were fed the aforementioned diets to satiation, three times a day, six days a week throughout the trial. Growth performance was significantly higher for the control group and values of P absorption (20.4–47.0%) and retention (14.0–36.3%) varied widely among the groups. Consequently, the total P loading (kg/t production) values based on retention fluctuated from 14.8 to 26.4 among the commercial diet groups compared with the low level of 8.5 for the control group. Similarly, the total N loading (kg/t production) values varied from 30.9 to 86.0 and was lowest for the control group. A higher whole body lipid and lower bone P and Ca confirmed the deficiency of the dietary available P in commercial diets. Better growth and comparatively less P and N loading rates were observed in the diet that had sufficient available P, not to mention that the control diet ranked best. It was concluded that an inadequacy of available P among the commercial diets affects the growth of carp and produces high P and N loading into the water. Therefore, if the commercial diets do not supply adequate levels of available P to carp, growth is negatively affected and may result in greater waste loading. 相似文献
107.
108.
Leptospiral lipopolysaccharide stimulates the expression of toll‐like receptor 2 and cytokines in pig fibroblasts
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Yijie Guo Tomokazu Fukuda Kenichiro Donai Kengo Kuroda Mizuki Masuda Shuichi Nakamura Hiroshi Yoneyama Emiko Isogai 《Animal Science Journal》2015,86(2):238-244
Pigs throughout the world are afflicted with leptospirosis, causing serious economic losses and potential hazards to human health. Although it has been known that leptospiral lipopolysaccharide (L‐LPS) is involved in an immunological reaction between an antigen and a host cell, little is known about how the immune system of pigs can respond to L‐LPS. Here, we stimulated pig fibroblasts by L‐LPS and then quantitatively measured gene and protein expression levels of two toll‐like receptors (TLRs), TLR2 and TLR4, by real‐time PCR and Western blotting. As a result, expression of TLR2 was found to be significantly up‐regulated within 24 h after L‐LPS stimulation whereas induction of TLR4 expression was relatively weak. We also revealed that of myeloid differentiation primary response gene 88 (MyD88), interleukin 6 (IL‐6) and IL‐8 gene expressions were markedly up‐regulated by L‐LPS stimulation. These results may suggest that the pig cell can activate TLR2 rather than TLR4 by L‐LPS stimulation, thereby inducing expression of cytokines. 相似文献
109.
Katsutaka Oishi Naoki Ohkura Koji Kadota Manami Kasamatsu Kentaro Shibusawa Juzo Matsuda Kazuhiko Machida Shuichi Horie Norio Ishida 《Journal of circadian rhythms》2006,4(1):13-7
Background
Although the number of circulating immune cells is subject to high-amplitude circadian rhythms, the underlying mechanisms are not fully understood. 相似文献110.
Tomoyuki Katsube-Tanaka Nadar Khan Satoru Yamaguchi Takeshi Yamaguchi Shuichi Iida 《Plant Production Science》2016,19(3):401-410
Multigenic glutelins and monogenic globulin are major storage proteins accumulating in vacuole-derived protein body (PB-II) of rice (Oryza sativa L.) seeds. Because their interplay in PB-II formation was scarcely known, the effect of globulin-less mutation on glutelin accumulation was investigated. In globulin-less mutants, no phenotypic defect was found in seed and plant growth, while PB-II was deformed and apparent glutelin composition was changed, producing new glutelin α polypeptides X1–X5. 2D-PAGE of different combinations of globulin-less and glutelin subunit mutations suggested that the X1/X2, X3, and X4/X5 were derived from glutelin GluB1/GluB2/GluB4, GluA3, and GluA1/GluA2 subunits, respectively. Western blot with glutelin GluB4 subunit-specific and its variable region discriminable antibodies indicated at least in part the new spots X1/X2 are partially degraded products of GluB4 α polypeptides by the removal of 2–39 residues from C-terminus. Time course experiments with maturing seeds indicated the partial degradation of GluB4 occurred earlier (from 7 days after flowering) and higher than that of GluA1/GluA2. Considering the above results together with the fact that globulin accumulates at the periphery of PB-II and its absence produces deformed PB-II, globulin protects glutelins from proteinase digestion and thereby facilitates stable glutelin accumulation. 相似文献