Total venous inflow occlusion in the normothermic dog: a study of haemodynamic, metabolic and neurological consequences     

G.B. Hunt  R. Malik  C.R. Bellenger  M.R.B. Pearson 《Research in veterinary science》1992,52(3):605-377

The acute haemodynamic and metabolic repercussions of total venous inflow occlusion were evaluated in six normal dogs, each of which underwent two four minute occlusions and one eight minute occlusion at normothermia. A further three dogs underwent a single eight minute period of occlusion and were allowed to recover from anaesthesia. Total venous inflow occlusion was well tolerated by all animals. They remained in sinus rhythm at the completion of occlusion, and unassisted haemodynamic recovery occurred rapidly. Recovery was quicker after four minutes than after eight minutes. There was no clinically detectable neurological impairment in three dogs which were allowed to recover.  相似文献   

Toxicity of p-aminophenol and p-nitrophenol to Chlorella vulgaris and two species of Nostoc isolated from soil     

M. Megharaj  H. W. Pearson  K. Venkateswarlu 《Pesticide biochemistry and physiology》1991,40(3)

An examination was made of the effects of p-aminophenol (PAP) treatment individually and in combination with its parent compound, p-nitrophenol (PNP), on growth and metabolic activities of a microalga, Chlorella vulgaris, and two cyanobacteria, Nostoc linckia and Nostoc muscorum, all isolated from soil. Comparatively, the cyanobacteria were more sensitive to the phenol treatments. All but the lowest (2 μg ml⁻¹) PAP treatments inhibited cell number, chlorophyll a, and total carbohydrate production, ¹⁴CO₂ uptake, and nitrate reductase and nitrogenase activity. The algistatic effect in C. vulgaris caused by PAP could not be reverted even in the presence of acetate (0.1%). However, the inherent toxic effect of PNP established toward the alga and cyanobacteria was found alleviated in the presence of PAP only at lower concentrations. Transmission electron microscopy revealed many cytological abnormalities in Chlorella vulgaris under the influence of the selected phenols, indicating that the toxicants directly interfere with membrane properties and enzymes.  相似文献   

A database survey of equine tumours in the United Kingdom          下载免费PDF全文

E. J. Knowles  W. H. Tremaine  G. R. Pearson  T. S. Mair 《Equine veterinary journal》2016,48(3):280-284

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Surgical management of refractory nasal aspergillosis using iodine cadexomer dressings in three dogs          下载免费PDF全文

TJ Preston  GL Hosgood  AEH Paul 《Australian veterinary journal》2016,94(11):405-410

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Alphaherpesvirus‐associated disease in greater bilbies (Macrotis lagotis)          下载免费PDF全文

AS Besier  TJ Mahony  M Crockford  JL Gravel  TF Chapman  MA O'Dea 《Australian veterinary journal》2016,94(6):208-212

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Distal Normograde Intramedullary Pin and Locking Plate Placement in the Canine Humerus: A Cadaveric Study          下载免费PDF全文

Tim Pearson  Mark Glyde  Giselle Hosgood  Lucas Beierer 《Veterinary surgery : VS》2016,45(7):879-886

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The goat as a sentinel for Venezuelan equine encephalomyelitis virus activity     

G A Erickson  C J Maré  J E Pearson  E A Carbrey 《American journal of veterinary research》1974,35(12):1533-1536

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Identifying experimental units and calculatng expnrimental error     

Teicher MH  Pearson DE  Shaywitz BA  Cohen DJ 《Science (New York, N.Y.)》1981,213(4510):931

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A possible cause for the 'pink-eye-like' condition in red deer     

Pearson AB 《New Zealand veterinary journal》1984,32(7):119

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Exploring relationships between body condition score,body fat,activity level and inflammatory biomarkers          下载免费PDF全文

W. Pearson  K. Wood  S. Stanley  J. MacNicol 《Journal of animal physiology and animal nutrition》2018,102(4):1062-1068

Obesity is associated with inflammatory disorders in humans, including degenerative joint disease. While obesity is endemic in horses, its relationship to equine degenerative joint disease has not been explored. The current study sought to describe relationships between: body weight (BW), body condition score (BCS), lameness grade (AAEP), total body fat mass (kg; FM) and fat per cent (FP) [multifrequency bioelectrical impedance analysis (mfBIA)], age, gender, activity level (AL), synovial fluid (SF) and plasma (PL) PGE₂ and glycosaminoglycan (GAG) in horses. During this field investigation, the BCS (of nine) of 54 horses at multiple farms in southern Ontario, Canada, was determined. Horses were categorized as thin (BCS=3/9; n = 6), moderate (BCS=4 or 5/9; n = 18), overweight (BCS=6 or 7/9; n = 19) or obese (BCS=8 or 9/9; n = 11). Total fat mass (kg) and body fat% was measured using mfBIA, lameness was assessed (AAEP lameness scale) and synovial fluid was collected via aseptic arthrocentesis from the left intercarpal joint for assessment of inflammatory biomarkers (PGE₂, GAG). Means were compared with a one‐way ANOVA; correlation coefficients were calculated using a Spearman Rank Order Correlation to reveal correlations between variables. BCS was positively correlated with BW, FM, FP, AL and PL‐PGE₂. BW was also significantly positively correlated with PL‐PGE₂. It is concluded that BCS is significantly correlated with PL‐PGE₂, due in part to the combined effect of AL and body condition. Net inflammatory effects of body fat on risk for joint disease require further study.  相似文献