Inhibited development of trichostrongylid worms in grazing cattle     

JP FABIYI  DB COPEMAN 《Australian veterinary journal》1989,66(8):240-242

Inhibition of development of gastro-intestinal trichostrongylid worms was studied using successive groups of tracer calves and groups of continuously grazed calves over one year in the Tully area of North Queensland lowland wet tropics. The results, assessed by means of worms from these calves recovered at necropsy 3 weeks after their removal from pastures, showed inhibition in the development of Haemonchus placei and Cooperia punctata at the early fourth stage at the approach to and during the relatively dry period in the area. Inhibition was however minor and inhibited larvae formed but only a small percentage of worm burdens in both categories of calves, indicating that they were not in any way of major epidemiological importance. It was suggested that the minor nature of inhibition was due to the mild climatic conditions which could not produce appropriate conditioning treatment, or caused only mild selection pressure for inhibition in the area.  相似文献   

Effects of 25% propylene glycol hydrogel (Solugel) on second intention wound healing in horses     

Dart AJ  Cries L  Jeffcott LB  Hodgson DR  Rose RJ 《Veterinary surgery : VS》2002,31(4):309-313

OBJECTIVE: To evaluate the effect of a commercially available 25% propylene glycol hydrogel preparation (Solugel; Johnson and Johnson Medical, North Ryde, Australia) on healing of full-thickness skin wounds on the distal aspect of the limb in horses. STUDY DESIGN: Experimental. ANIMALS: Eight Standardbred horses. METHODS: Standardized (2.5 x 2.5 cm) full-thickness skin wounds were created over the mid-dorsomedial aspect of both metacarpi in 8 horses. One wound in each horse was dressed with saline solution (0.9% NaCl) soaked gauze, and one was treated with Solugel under dry regular gauze; wounds were then bandaged with gauze-coated cotton wool and elastic adhesive bandages. Wounds were videorecorded and rebandaged twice weekly until healed. Wound healing variables were measured from the videorecordings using a computer software package and analyzed as a randomized complete block design with repeated measures. Where necessary variables were made positive for analysis; significance was set at P <.05. RESULTS: The area of the wound at the first bandage change did not vary between treated and untreated wounds. Treatment had no effect on the total rate of healing, rate of healing during the retraction phase of healing, rate of healing after the retraction phase was complete, or the amount the wounds retracted. CONCLUSIONS: Using this model of wound healing, Solugel had no effect on second intention healing of distal limb wounds in horses. CLINICAL RELEVANCE: Solugel does not appear to have any beneficial effect on healing of small full-thickness skin wounds to the distal limb of horses.  相似文献   

IMMUNOPROPHYLAXIS WITH BCG OF EXPERIMENTAL ECHINOCOCCUS MULTILOCULARIS INFECTIONS     

J. M. Reuben  C. E. Tanner 《Australian veterinary journal》1979,55(3):105-108

SUMMARY: Infection by the metacestodes of Echinococcus multilocularis is an example of the biological paradox of a proliferating parasite in an immunologically-competent host. There is evidence that infection with these organisms is regulated. A study of this regulation has shown that hydatid cysts can be effectively treated with complement and that the cellular defence mechanisms of the host can be non-specifically activated with BCG; treatment with BCG presents an effective prophylactic measure against infection with E. multilocularis . The mechanisms by which parasite infections are regulated can furnish clues to possible prophylactic and therapeutic strategies.  相似文献   

江苏省实施兽药GSP试点工作的基本做法与推进思考     

时勇  周春红  颜京平  毕昊容 《中国兽药杂志》2007,41(3):40-43

江苏省GSP试点工作通过加强组织领导、广泛宣传推动、强化培训指导和注重检查交流等措施,基本建立了兽药GSP制度的框架,进一步提高和统一了对兽药GSP的认识,提高了试点企业的质量管理水平。但在兽药GSP实施过程中,存在对其重要性认识不足,部分暂行管理办法内容与实际脱节,技术指导力量薄弱等问题。  相似文献   

Cell biology. Ancient sensor for ancient drug     

Shaw RJ  Cantley LC 《Science (New York, N.Y.)》2012,336(6083):813-814

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Avian influenza in Australia: a summary of 5 years of wild bird surveillance          下载免费PDF全文

VL Grillo  KE Arzey  PM Hansbro  AC Hurt  S Warner  J Bergfeld  GW Burgess  B Cookson  CJ Dickason  M Ferenczi  T Hollingsworth  MDA Hoque  RB Jackson  M Klaassen  PD Kirkland  NY Kung  S Lisovski  MA O'Dea  K O'Riley  D Roshier  LF Skerratt  JP Tracey  X Wang  R Woods  L Post 《Australian veterinary journal》2015,93(11):387-393

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Recharge in Volcanic Systems: Evidence from Isotope Profiles of Phenocrysts   总被引：2，自引：0，他引：2  

JP Davidson  FJ Tepley 《Science (New York, N.Y.)》1997,275(5301):826-829

Strontium isotope ratios measured from core to rim across plagioclase feldspar crystals can be used to monitor changes in the isotope composition of the magma from which they grew. In samples from three magma systems from convergent margin volcanoes, sudden changes in major element composition, petrographic features, and strontium isotope composition were found to correspond to discrete magmatic events, most likely repeated recharge of more mafic magma with lower ratios of strontium-87 to strontium-86 into a crustally contaminated magma.  相似文献   

Quality management in Israel’s agriculture     

Reuben Ausher 《Phytoparasitica》2001,29(4):279-283

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Behavioural and EEG changes in sheep in response to painful acute electrical stimuli     

RM ONG  JP MORRIS  JK O'DWYER  JL BARNETT  PH HEMSWORTH  IJ CLARKE 《Australian veterinary journal》1997,75(3):189-193

Objective To measure acute pain in sheep, based on a human pain model, and examined changes in both electroencephalogram frequency spectrum and behavioural responses to increased electrical stimulation in sheep. Design Analysis of variance (treatment and animal effects) for stimulus intensity where each animal received each electric shock treatment given in the order 0, 5,10 and 20 mA. Procedure Eight sheep with electrodes implanted over the surface of the brain were examined for escape-avoidance and electroencephalogram responses to four levels of electrical stimulation from 0–20 mA. Results With increasing stimulus intensity at the time of feeding, the sheep were more hesitant to return to the feeder or remain near the feeder following stimulation. There was little difference between the 0 and 5 mA stimuli for any of the behaviour variables (P > 0.05). However, there were marked increases in the time taken to re-approach the feeder after receiving an electric shock of 5 mA and of 20 mA (P < 0.05; mean values 3 and 119 s, respectively) and remaining near the feeder for 5 s (P < 0.001; mean values 10 and 167 s, respectively). Following the stimulus, there was an overall increase in the electroencephalogram power spectrum in the first four seconds, which then rapidly returned to normal. In particular, the 20 mA stimulus resulted in higher absolute power values than in the control (0 mA) treatment for delta 2 (P < 0.001), theta 1 (P < 0.05), theta 2 (P < 0.05), alpha 1 (P < 0.001), alpha 2 (P < 0.001) and beta 1 (P < 0.01) band-widths. Similarly, for the 10 mA stimulus, the absolute power values were greater than the control treatment for delta 2 (P < 0.05), alpha 1 (P < 0.01), alpha 2 (P < 0.001) and beta 1 (P < 0.01) bandwidths. Conclusion The experiment suggests that a human acute pain model is applicable to sheep and that these electroencephalogram changes may provide a good measure of acute pain in sheep.  相似文献   

Effect of adjuvants on antibody responses of sheep immunised with recombinant pili from Dichelobacter nodosus     

AK WALDUCK  JP OPDEBEECK 《Australian veterinary journal》1996,74(6):451-455

Objective To compare the effects of two oil emulsion adjuvants (incomplete Freunds adjuvant and a proprietary oil adjuvant), DEAE-dextran, L-tyrosine particles and Quil A on the humoral immune responses of sheep immunised with recombinant pili of Dichelobacter nodosus (strain A).
Procedure Antibody titres were studied for up to 32 weeks and were measured by bacterial agglutination and ELISA. The relative avidity of antibodies for pili was determined and the incidence and severity of adverse reactions at the site of injection of vaccines were recorded.
Results The oil emulsion adjuvants and Quil A were more effective than either DEAE-dextran or L-tyrosine at stimulating antibodies in sheep. The incidence and severity of adverse reactions was lower in sheep which received vaccines containing either Quil A or DEAE-dextran than in sheep which received vaccines containing oil emulsion adjuvants. L-tyrosine had no adverse effects.
Conclusion Quil A was as effective as oil adjuvants at stimulating high levels of antibodies against recombinant pili in sheep and had the significant advantage of being less irritant after subcutaneous injection.  相似文献