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71.
72.
N. GYRD-HANSEN FOLKE RASMUSSEN MOGENS SMITH 《Journal of veterinary pharmacology and therapeutics》1981,4(1):15-25
Tetracycline chloride dissolved in saline was injected intravenously to seven cows. Two doses of tetracycline were used: 5 and 10 mg/kg b.wt, and the injections were given over a period of either 10, 60 or 300 sec.
A number of the cows collapsed shortly after the injection was completed, usually when the 10 mg dosage was given in 60 sec. When the same dose was given over a period of 5 min none of the cows collapsed. A more or less pronounced drop in blood pressure could be detected during or shortly after the injection; in those cows which collapsed the blood pressure fell almost to zero. The predominant change in pulse rate in connection with the tetracycline administration was a decrease which could be quite marked, pulse rates falling as low as 10–20 per min. Simultaneously with these changes in blood pressure and pulse rate severe abnormalities in ECG could be observed. Pre-treatment with a normal therapeutic dose of calcium borogluconate intravenously prevented collapse in the cows and diminished the drop in blood pressure associated with an ensuing tetracycline injection.
It is concluded that intravenous injection of tetracycline is hazardous, but that collapse can be avoided by giving the injection very slowly over a period of no less than 5 min. 相似文献
A number of the cows collapsed shortly after the injection was completed, usually when the 10 mg dosage was given in 60 sec. When the same dose was given over a period of 5 min none of the cows collapsed. A more or less pronounced drop in blood pressure could be detected during or shortly after the injection; in those cows which collapsed the blood pressure fell almost to zero. The predominant change in pulse rate in connection with the tetracycline administration was a decrease which could be quite marked, pulse rates falling as low as 10–20 per min. Simultaneously with these changes in blood pressure and pulse rate severe abnormalities in ECG could be observed. Pre-treatment with a normal therapeutic dose of calcium borogluconate intravenously prevented collapse in the cows and diminished the drop in blood pressure associated with an ensuing tetracycline injection.
It is concluded that intravenous injection of tetracycline is hazardous, but that collapse can be avoided by giving the injection very slowly over a period of no less than 5 min. 相似文献
73.
Summary. Pigweed ( Amaranthus sp.) control was not satisfactory where furrow irrigation was substituted for mechanical incorporation of nitralin or trifluralin on loam. Trifluralin concentrations in soil were twice as high after mechanical incorporation compared to furrow irrigation alone. In some instances, nitralin gave excellent pigweed control when rainfall occurred within 1 day after application. However, weed control was not consistent over a 3-year period. When herbicides were applied through a sprinkler irrigation system, chemicals were retained in the upper 5 cm of loamy sand and did not leach. However, herbicide distribution was not uniform due to irregular water movement by wind during application. Trifluralin did not control pigweed when applied and incorporated by sprinkler irrigation. Under the same conditions, nitralin gave good to excellent control.
Incorporation de la nitraline et de la trifluraline par la pluie et par I'irrigation 相似文献
Incorporation de la nitraline et de la trifluraline par la pluie et par I'irrigation 相似文献
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75.
Experimental colibacillosis in gnotobiotic piglets exposed to 3 enterotoxigenic serotypes 总被引:1,自引:0,他引:1
Three strains of enterotoxigenic Escherichia coli (ETEC) (064:KSNT, K88ac; 020:KSNT, K88ac and 08:K85ab, K99) originally cultured from outbreaks of diarrhoea in piglets a few hours old, were administered orally to gnotobiotic piglets. There was a marked age-related difference in the clinical response to infection between the 3 strains although they all produced heat-stable toxin. All 3 strains produced severe clinical signs of depression, anorexia, vomiting, diarrhoea, followed by dehydration and death in one-day-old piglets. In piglets infected at 3 days of age the two K88+ ETEC caused diarrhoea and death but the K99+ ETEC induced moderate diarrhoea only. In piglets infected at 7 days of age, the 064 strain produced severe diarrhoea and death, and 020 strain caused mild diarrhoea in 3 of 6 piglets with one death while the 08 strain caused no illness. Pathological changes in the intestinal tract associated with these infections were minimal, or absent. Immunofluorescent staining with homologous hyperimmune sera demonstrated adherence of the 3 ETEC strains to the brush border of small intestinal epithelial cells. Fluorescing organisms were observed in all infected piglets irrespective of the severity of clinical signs but the degree and extent of colonisation varied with the age of the piglets and the infecting strain. This may explain the difference in clinical response between the 3 strains. 相似文献
76.
77.
78.
Long-term effects of topectomy showed statistically significant losses not present shortly after psychosurgery in eight of 14 psychological test measures. Site of operation, length of postoperative interval, age, and nature of the measure were factors determining the effects of brain damage. 相似文献
79.
80.