Correlation Between Histopathologic,Arthroscopic, and Magnetic Resonance Imaging Findings in Dogs With Medial Coronoid Disease          下载免费PDF全文

Vincent Wavreille DVM  Wm Tod Drost DVM  Diplomate ACVR  Duncan Russell BVMS  Diplomate ACVP  Matthew J. Allen Vet MB  PhD 《Veterinary surgery : VS》2015,44(4):501-510

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Trephination of the Frontal Sinuses and Instillation of Clotrimazole Cream: A Computed Tomographic Study in Canine Cadavers     

Martin Baker BSc CertPG  Lindsay White MA Vet MB 《Veterinary surgery : VS》2013,42(3):322-328

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A preliminary investigation comparing pre-operative morphine and buprenorphine for postoperative analgesia and sedation in cats   总被引：2，自引：1，他引：1  

GW Stanway BVSC  Cert VA    PM Taylor MA  Vet MB  PhD  DVA  Dip ECVA  & DC Brodbelt† MA  Vet MB  DVA  Dip ECVA  MRCVS 《Veterinary anaesthesia and analgesia》2002,29(1):29-35

Objective To compare the postoperative analgesic and sedative properties of buprenorphine and morphine in cats. Study Design Prospective, randomized, blinded study. Animals Thirty‐two domestic cats undergoing surgery. Methods Cats received pre‐anaesthetic medication with acepromazine (0.05 mg kg^?1) given intramuscularly and were randomly allocated to group M and given morphine (0.1 mg kg^?1) intramuscularly (IM) or to group B and given buprenorphine (0.01 mg kg^?1) IM. Anaesthesia was induced with propofol and maintained with halothane in oxygen and nitrous oxide. Pain and sedation scores using visual analogue scales, and heart and respiratory rates, were measured immediately before, and 30, 60, 120, 180, 300 and 420 minutes after anaesthesia. Results Pain scores were significantly lower at 60, 120 and 180 minutes after anaesthesia in group B. Group B also had higher heart rates at 30 minutes. There were no other statistically significant differences between the groups. Clinical relevance Buprenorphine (0.01 mg kg^?1) appeared to provide better postoperative analgesia than morphine (0.1 mg kg^?1) and may also have a longer duration of action.  相似文献   

BALLOON DILATATION OF NASOPHARYNGEAL STENOSIS IN A CAT     

Adrian  Boswood  Vet MB  Christopher R.  Lamb  Vet MB  Daniel J.  Brockman  BVSC  Panagiotis  Mantis  DVM  Angela L.  Witt  DVM 《Veterinary radiology & ultrasound》2003,44(1):53-55

A cat was diagnosed with nasopharyngeal stenosis on the basis of clinical signs, survey and contrast radiography, endoscopy and magnetic resonance imaging. The condition was successfully managed with repeated balloon dilatation.  相似文献   

Collection and Propagation Methods for Mesenchymal Stromal Cells     

Sarah E. Taylor BVM&S  MSc  PhD  Cert ES  MRCVS  Peter D. Clegg MA  Vet MB  PhD 《Veterinary Clinics of North America: Equine Practice》2011,27(2):263-274

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Intravenous anaesthesia using detomidine, ketamine and guaiphenesin for laparotomy in pregnant pony mares     

Polly M Taylor  MA  VetMB  PhD  DVA  MRCVS  Stelio PL Luna  DVM  PhD  Kate L White MA  Vet MB  CertVA  MRCVS  Malcolm Bloomfield  Abigail L Fowden MA  PhD 《Veterinary anaesthesia and analgesia》2001,28(3):119-125

Objective To characterize intravenous anaesthesia with detomidine, ketamine and guaiphenesin in pregnant ponies. Animals Twelve pony mares, at 260–320 days gestation undergoing abdominal surgery to implant fetal and maternal vascular catheters. Materials and methods Pre‐anaesthetic medication with intravenous (IV) acepromazine (30 µg kg^?1), butorphanol (20 µg kg^?1) and detomidine (10 µg kg^?1) preceded induction of anaesthesia with detomidine (10 µg kg^?1) and ketamine (2 mg kg^?1) IV Maternal arterial blood pressure was measured directly throughout anaesthesia and arterial blood samples were taken at 20‐minute intervals for measurement of blood gases and plasma concentrations of cortisol, glucose and lactate. Anaesthesia was maintained with an IV infusion of detomidine (0.04 mg mL^?1), ketamine (4 mg mL^?1) and guaiphenesin (100 mg mL^?1) (DKG) for 140 minutes. Oxygen was supplied by intermittent positive pressure ventilation (IPPV) adjusted to maintain PaCO₂ between 5.0 and 6.0 kPa (38 and 45 mm Hg), while PaO₂ was kept close to 20.0 kPa (150 mm Hg) by adding nitrous oxide. Simultaneous fetal and maternal blood samples were withdrawn at 90 minutes. Recovery quality was assessed. Results DKG was infused at 0.67 ± 0.17 mL kg^?1 hour^?1 for 1 hour then reduced, reaching 0.28 ± 0.14 mL kg^?1 hour^?1 at 140 minutes. Arterial blood gas values and pH remained within intended limits. During anaesthesia there was no change in heart rate, but arterial blood pressure decreased by 10%. Plasma glucose and lactate increased (10‐fold and 2‐fold, respectively) and cortisol decreased by 50% during anaesthesia. Fetal umbilical venous pH, PO₂ and PCO₂ were 7.34 ± 0.06, 5.8 ± 0.9 kPa (44 ± 7 mm Hg) and 6.7 ± 0.8 kPa (50 ± 6 mm Hg); and fetal arterial pH, PO₂ and PCO₂ were 7.29 ± 0.06, 4.0 ± 0.7 kPa (30 ± 5 mm Hg) and 7.8 ± 1.7 kPa (59 ± 13 mm Hg), respectively. Surgical conditions were good but four ponies required a single additional dose of ketamine. Ponies took 60 ± 28 minutes to stand and recovery was good. Conclusions and clinical relevance Anaesthesia produced with DKG was smooth while cardiovascular function in mare and fetus was well preserved. This indicates that DKG infusion is suitable for maintenance of anaesthesia in pregnant equidae.  相似文献   

Unusual Patterns of Serum Antibodies to Streptococcus Equi in Two Horses with Purpura Hemorrhagica   总被引：1，自引：1，他引：0  

Sebastian E. Heath Vet MB  MVSc    Raymond J. Geor BVSc  MVSc    Henry Tabel DVM  PhD  Kathy Mcintosh DVM 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》1991,5(5):263-267

An enzyme-linked immunosorbent assay (ELISA) was developed for use in horses to determine serum titers of antibodies of the immunoglobulin classes IgA, IgG, and IgM to Streptococcus equi M-like protein and culture supernatant protein antigens. Serum antibodies were determined in 28 adult horses, including 9 horses with recent S. equi infections, 17 horses without known exposure to S. equi, but without a history of respiratory disease in the preceding 4 months, and 2 horses with clinical purpura hemorrhagica. Serum IgA titers to culture supernatant protein antigen were highest in recently infected horses (P less than 0.001). Serial determinations of antibody titers in the horses with purpura showed that IgG antibodies to both S. equi M-like protein and culture supernatant protein antigens were undetectable initially, but later rose coincidental with clinical recovery from the disease. Possible mechanisms for these findings are discussed.  相似文献   

Sinography in the Investigation of Draining Tracts in Small Animals: Retrospective Review of 25 Cases     

CHRISTOPHER R. LAMB MA  Vet MB  Diplomate ACVR    ROBERT N. WHITE BVetMed  CertVA  FINTAN J. McEVOY mvb  dvr 《Veterinary surgery : VS》1994,23(2):129-134

The signalment, history, clinical signs, radiographic findings, and surgical findings of 25 consecutive animals that had sinography were reviewed to assess the contribution made by sinography to diagnosing and surgically managing draining tracts in small animals. There were 23 dogs and 2 cats; a variety of breeds and both sexes were represented (18 males, 7 females). Before referral the mean duration of clinical signs was 9.8 months (range, 0.5 to 33 months) and a mean of 2.0 surgical procedures (range, 1 to 5) had been performed. Sinuses occurred in a variety of locations, most commonly the neck (10), head (6), and paws (5). The most common cause was foreign body (15). Survey radiographs showed abnormalities in 21 of 26 (78%) instances, including soft-tissue swelling (11), chronic-appearing periosteal reaction on adjacent bones (5), possible foreign body (4), and gas in soft tissues (2). Sinography (or fistulography) enabled definite diagnosis of the cause of the sinus (or fistula) in 15 of 26 (58%) instances and demonstrated 13 of 15 foreign bodies (sensitivity 87%; specificity 100%). Tracts caused by an esophageal perforation and otitis media were also correctly shown by fistulography. In 11 animals, sinography indicated that the position or extent of the lesion was different to that expected on the basis of clinical signs and survey radiographs.  相似文献   

Circulatory and blood gas changes accompanying the development and treatment of induced laminitis     

Carl A. Kirker-Head MA  Vet MB  Kay A. Stephens DVM  MS  Robert L. Toal DVM  MS  Dallas O. Goble DVM 《Journal of Equine Veterinary Science》1986,6(6):293-301

A peripheral vasodilatory agent, isoxsuprine hydro-chloride, was evaluated in a controlled study for its efficacy in the treatment of acute equine laminitis. Eight healthy, adulthorses of variable age and sex were used in the trial. Acute laminitis was induced in 5 of the horses by oral carbohydrate overload. Intravenous isoxsuprine therapy (1.8 mg/kg) was initiated in 3 of the horses receiving carbohydrate overload at first sign of clinical lameness and repeated at 12-hour intervals. Intravenous saline placebos were administered on a similar schedule to 2 control horses which also received a carbohydrate overload. The remaining 3 horses served as further controls. Local and systemic responses to induction of laminitis and isoxsuprine administration were assessed by subjective evaluation of clinical lameness in a double blind trial; nuclear scintigraphy and radiography of the distal forelimbs; and assessment of physical, hematological and biochemical parameters.

Pronounced tachycardia, hypotension and sweating accompanied the intravenous infusion of isoxsuprine. The 3 horses treated with isoxsuprine following the induction of laminitis showed a more rapid improvement in soundness than horses receiving saline placebos. No horse developed rotation of the third phalanx in response to the diet Nuclear scintigraphy indicated that blood perfusion patterns within the hoof of laminitic horses altered with isoxsuprine therapy, but an overall increase or decrease in perfusion was not apparent. Alterations in serum enzyme and electrolyte profiles with the onset of laminitis generally concurred with findings previously reported for this model of the disease. No change in coagulation profiles accompanied the onset of laminitis or isoxsuprine administration. Blood gas analysis indicated an increase in median palmar vein oxygen partial pressure (PO₂) levels with onset of laminitis. A concurrent decrease in the median palmar arteriovenous oxygen partial pressure difference (AVO₂) was significant at the P<0.01 level. There was no difference in median palmar vein PO₂ values between thoseanimals receiving isoxsuprine and those receiving saline placebo therapy. Results of the trialindicated that isoxsuprine may be beneficial in the treatment of acute laminitis. Further controlled studies are appropriate.  相似文献   

A Comparison of the Synthes 4.5-mm Cannulated Screw and the Synthes 4.5-mm Standard Cortex Screw Systems in Equine Bone     

SALLY A. COLGAN BVSc    AARON T. HECKER MS  CARL    A. KIRKER-HEAD MA  Vet MB  MRCVS  Diplomate ACVS  Diplomate ECVS  WILSON C. HAYES PhD 《Veterinary surgery : VS》1998,27(6):540-546

Objective —To determine risk of failure of the Synthes 4.5-mm cannulated screw system instrumentation in equine bone and to compare its application with the Synthes 4.5-mm standard cortex screw system.
Study Design —The maximum insertion torque of the cannulated and standard cortex screw systems were compared with the ultimate torsional strengths of the equipment. Pullout strength and ultimate tensile load of cannulated and standard cortex screws were also determined.
Sample Population—Paired equine cadaver third metacarpal and third carpal bones.
Methods —Maximum insertion torque and ultimate torsional strengths were determined by using an axial-torsional, servohydraulic materials testing system and a hand-held torquometer. Pullout tests were performed by using a servohydraulic materials testing system.
Results —Maximum insertion torque of all cannulated instrumentation was less than ultimate torsional strength at all locations ( P < .05). Maximum insertion torques of cannulated taps and screws were greater than for standard taps and screws in the third carpal bone ( P < .002). Pullout strength of the cannulated screws was less than the standard cortex screws at all sites ( P < .001). Cannulated screws broke before bone failure in all but one bone specimen. Conclusions—The risk of cannulated instrument or screw failure during insertion into bone is theoretically low. The relatively low pullout strength of the cannulated screws implies that the interfragmentary compression achievable is likely to be less than with standard cortex screws. Clinical Relevance—The relatively low pullout strength of the cannulated screw suggests that its risk of failure during fracture repair is greater than with the standard cortex screw.  相似文献