Coagulation abnormalities associated with acute Angiostrongylus vasorum infection in dogs     

C G Schelling  C E Greene  A K Prestwood  V C Tsang 《American journal of veterinary research》1986,47(12):2669-2673

Ten dogs were experimentally infected with 150 3rd-stage larvae of the lungworm Angiostrongylus vasorum (Baillet, 1866). Blood samples obtained once a week for 5 weeks after infection was induced were examined for coagulation alterations. Thrombocytopenia developed in infected dogs before and after parasitic patency, which occurred 6 weeks after infection was induced. Prolongation of activated partial thromboplastin time and thrombocytopenia initially were associated with periods of larval migration and, later, at patency, with pulmonary egg embolism and hatching of 1st-stage larvae in the lung. Decreased factor-V activity, significantly shortened values for the prothrombin time, and increased factor-VIII activity were evident during postpatent periods of parasitic infection. Significant changes were not found in factors-XII and -IX activities throughout the course of infection. Coagulation abnormalities were attributed to excessive intravascular coagulation. Immature adults and first stages of the parasite seemed to have initiated the coagulopathy in the prepatent phase of infection, with subsequent coagulation abnormalities occurring at the time of patency.  相似文献   

Late Pleistocene Desiccation of Lake Victoria and Rapid Evolution of Cichlid Fishes     

TC Johnson  CA Scholz  MR Talbot  K Kelts  RD Ricketts  G Ngobi  K Beuning  I Ssemmanda  JW McGill 《Science (New York, N.Y.)》1996,273(5278):1091-1093

Lake Victoria is the largest lake in Africa and harbors more than 300 endemic species of haplochromine cichlid fish. Seismic reflection profiles and piston cores show that the lake not only was at a low stand but dried up completely during the Late Pleistocene, before 12,400 carbon-14 years before the present. These results imply that the rate of speciation of cichlid fish in this tropical lake has been extremely rapid.  相似文献   

Factors Associated with Colostrum Quality and Effects on Serum Gamma Globulin Concentrations of Calves in Swiss Dairy Herds          下载免费PDF全文

C. Reschke  E. Schelling  A. Michel  F. Remy‐Wohlfender  M. Meylan 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2017,31(5):1563-1571

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