Efficacy of permethrin in controlling the Australian paralysis tick Ixodes holocyclus and the cat flea Ctenocephalides felis on dogs     

BF STONE  MA SHIPSTONE  KV MASON  M. CUNNINGHAM  CW WONG 《Australian veterinary journal》1994,71(3):90-91

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Assessment of bacterial contamination of three multidose ophthalmic solutions     

Betbeze CM  Stiles J  Krohne SG 《Veterinary ophthalmology》2007,10(2):81-83

OBJECTIVE: To investigate the frequency of bacterial contamination of multidose proparacaine hydrochloride, tropicamide, and eyewash bottles used in veterinary ophthalmology examination rooms during normal operating procedures. METHODS: Three representative bottles each of proparacaine hydrochloride, tropicamide, and purified water eye wash were opened at the same time, numbered, and placed into small animal examination rooms. Doctors, students and technicians who were using the solutions were blinded to the study. Aerobic cultures were obtained at the time of opening (time 0), at 1 week (time 1), and at 2 weeks after opening (time 2) the bottles. The sites cultured included a drop of each solution, the inside of the bottle cap, the tip of the bottle, and the bottle threads and medication residue found in these threads. RESULTS: Aerobic cultures of tropicamide and proparacaine had no growth of bacteria from any of the evaluated sites. Staphylococcus epidermidis was cultured from the tip of one bottle of eye wash after 1 week. CONCLUSIONS: We conclude that proparacaine, tropicamide, and eyewash solutions used in veterinary examination rooms are adequately preserved for use in ophthalmic examination. They have a low level of bacterial contamination 1 or 2 weeks after opening when used and stored according to the recommendations of the product manufacturers and previous studies.  相似文献   

Titan's rotation reveals an internal ocean and changing zonal winds     

Lorenz RD  Stiles BW  Kirk RL  Allison MD  Del Marmo PP  Iess L  Lunine JI  Ostro SJ  Hensley S 《Science (New York, N.Y.)》2008,319(5870):1649-1651

Cassini radar observations of Saturn's moon Titan over several years show that its rotational period is changing and is different from its orbital period. The present-day rotation period difference from synchronous spin leads to a shift of approximately 0.36 degrees per year in apparent longitude and is consistent with seasonal exchange of angular momentum between the surface and Titan's dense superrotating atmosphere, but only if Titan's crust is decoupled from the core by an internal water ocean like that on Europa.  相似文献   

Cassini radar views the surface of Titan     

Elachi C  Wall S  Allison M  Anderson Y  Boehmer R  Callahan P  Encrenaz P  Flamini E  Franceschetti G  Gim Y  Hamilton G  Hensley S  Janssen M  Johnson W  Kelleher K  Kirk R  Lopes R  Lorenz R  Lunine J  Muhleman D  Ostro S  Paganelli F  Picardi G  Posa F  Roth L  Seu R  Shaffer S  Soderblom L  Stiles B  Stofan E  Vetrella S  West R  Wood C  Wye L  Zebker H 《Science (New York, N.Y.)》2005,308(5724):970-974

The Cassini Titan Radar Mapper imaged about 1% of Titan's surface at a resolution of approximately 0.5 kilometer, and larger areas of the globe in lower resolution modes. The images reveal a complex surface, with areas of low relief and a variety of geologic features suggestive of dome-like volcanic constructs, flows, and sinuous channels. The surface appears to be young, with few impact craters. Scattering and dielectric properties are consistent with porous ice or organics. Dark patches in the radar images show high brightness temperatures and high emissivity and are consistent with frozen hydrocarbons.  相似文献   

Musculoskeletal responses of 2-year-old Thoroughbred horses to early training. 4. Morphometric,microscopic and biomechanical properties of the digital tendons of the forelimb     

EC Firth  CW Rogers  BH Anderson 《New Zealand veterinary journal》2013,61(5):285-292

AIM: To determine the weight, volume, density and cross-sectional area (CSA) of the digital flexor tendons, common digital extensor tendon (CDET) and suspensory ligament (SL) of the forelimb of young Thoroughbred horses in early training, and to assess the response to a training programme of known parameters of superficial digital flexor tendon (SDFT) tissue at mid-metacarpal level.

METHODS: The tendons of seven 2-year-old Thoroughbred horses in training were inspected, transected into segments of known length, and compared with those from seven untrained horses matched for age, sex and breed. The weight, volume, density and CSA of each segment, and the crimp angle, histological features, and biomechanical ultimate stress and stiffness of tendon samples from the mid-metacarpal region of the SDFT were determined.

RESULTS: There was no macroscopic evidence of swelling or discolouration in any of the tendon segments or cut surfaces. The volumes of SDFT and CDET segments of horses in the trained group were significantly greater than those in the untrained group (p=0.036 and p=0.039, respectively). A greater increase in volume than weight resulted in a lower density in the SDFT but not CDET in trained compared with untrained horses (p=0.038). CSA of these two tendons was significantly greater in the trained group (p=0.002 and 0.036, respectively), the percentage increase being greater in the CDET than the SDFT. The number of tenocytes at four sites in the mid-metacarpal SDFT region was less in trained than untrained horses (p=0.025). There was no histological evidence of inflammation, and no difference in crimp angle between groups. There was no significant between-group difference in stiffness or ultimate stress of tendon strips.

CONCLUSIONS: Volume and CSA of the SDFT and CDET were larger in trained than untrained horses. The SDFT was less dense in the trained group. Because no evidence of tendonitis was detected and training appeared to have no significant effect on crimp angle or biomechanical properties of tendon strips, the size and density changes were presumed to be adaptive and induced by the training.

CLINICAL RELEVANCE: Although evident in this in vitro study, the detection of adaptive from initial pathological increase in size of the SDFT is likely to be difficult in vivo.  相似文献   

Physics. A new spin on the Doppler effect     

McMichael RD  Stiles MD 《Science (New York, N.Y.)》2008,322(5900):386-387

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A cell-cycle constraint on the regulation of gene expression by platelet-derived growth factor   总被引：7，自引：0，他引：7  

B J Rollins  E D Morrison  C D Stiles 《Science (New York, N.Y.)》1987,238(4831):1269-1271

In density-arrested monolayer cultures of Balb/c 3T3 cells, platelet-derived growth factor (PDGF) stimulates expression of the c-myc and c-fos proto-oncogenes, as well as the functionally uncharacterized genes, JE, KC, and JB. These genes are not coordinately regulated. Under ordinary conditions, c-fos, JE, KC, and JB respond to PDGF only when the cells are in a state of G0 growth arrest at the time of PDGF addition. The c-myc gene is regulated in opposition to the other genes, responding best to PDGF in cycling cultures.  相似文献