Tolerability and efficacy of benazepril in cats with chronic kidney disease     

King JN  Gunn-Moore DA  Tasker S  Gleadhill A  Strehlau G;Benazepril in Renal Insufficiency in Cats Study Group 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2006,20(5):1054-1064

The objective of the study was to test the effect of the angiotensin-converting enzyme inhibitor (ACEI) benazepril in cats with chronic kidney disease (CKD). A total of 192 cats with CKD with an initial plasma creatinine concentration > or = 2 mg/dL (> or = 177 micromol/L) and urine specific gravity < or = 1.025 were recruited into a double-blind, parallel-group, prospective, randomized clinical trial. Cats received daily (q24h) PO placebo (n = 96) or benazepril x HCl at a dosage of 0.5-1.0 mg/kg (n = 96) for up to 1,119 days. Most cats were fed exclusively a diet containing low amounts of phosphate, protein, and sodium. Benazepril produced a significant reduction in proteinuria, assessed by the urine protein-to-creatinine ratio (UPC, P = .005). This effect of benazepril was present in all subgroups tested, including cats with UPC <0.2, although the effect was largest in cats with higher UPCs. Plasma protein was maintained at higher concentrations with benazepril as compared with placebo during treatment in cats with initial UPC <1 (P = .038 versus P = .079 for all cats). There was no difference in renal survival time between the 2 groups when all 192 cats were compared. Mean +/- SD renal survival times were 637 +/- 480 days with benazepril and 520 +/- 323 days with placebo (P = .47). Mean +/- SD renal survival times in the 13 cats with initial UPC > or = 1 were 402 +/- 202 days with benazepril and 149 +/- 90 days with placebo (P = .27). Cats with initial UPC > or = 1 treated with benazepril had better appetite (P = .017) as compared with those treated with placebo. Benazepril was well tolerated. In conclusion, benazepril decreased proteinuria in cats with CKD.  相似文献   

发达国家发展循环农业的经验及对中国的启示   总被引：2，自引：0，他引：2  

中国农业大学经济管理学院URP科研组 《世界农业》2009,(7)

本文通过分析美国、日本、英国、德国四国关于循环农业方面的政策和经验教训,结合中国循环农业的现状,分析中国相关政策存在的不足,提出了促进中国发展农业循环经济政策的相应措施.  相似文献   

Randomized controlled trial of the efficacy of cyclosporine in the treatment of atopic dermatitis in dogs     

Olivry T  Steffan J  Fisch RD  Prélaud P  Guaguère E  Fontaine J  Carlotti DN;European Veterinary Dermatology Cyclosporine Group 《Journal of the American Veterinary Medical Association》2002,221(3):370-377

OBJECTIVE: To evaluate efficacy of cyclosporine A, administered at either of 2 dosages, in dogs with atopic dermatitis (AD). DESIGN: Multicenter randomized controlled trial. ANIMALS: 91 dogs with AD. PROCEDURE: Dogs were assigned to receive placebo (30 dogs), cyclosporine at a low dosage (2.5 mg/kg [1.1 mg/lb], PO, q 24 h for 6 weeks; 30 dogs), or cyclosporine at a high dosage (5.0 mg/kg [2.3 mg/lb], PO, q 24 h for 6 weeks; 31 dogs). RESULTS: After 6 weeks, mean percentage reductions, compared with baseline scores, in scores of lesion severity were 34, 41, and 67% for dogs treated with the placebo, cyclosporine at the low dosage, and cyclosporine at the high dosage, respectively. Similarly, mean percentage reductions in pruritus scores were 15, 31, and 45%, respectively. Percentage reductions in skin lesion and pruritus scores were significantly higher for dogs given cyclosporine at the high dosage than for dogs given the placebo. Treatment efficacy was significantly associated with whether dogs had a history of seasonal AD. Percentage reductions in skin lesion and pruritus scores were high for dogs treated with cyclosporine at the highest dosage that had a history of nonseasonal AD. Dogs in all groups with seasonal AD improved during the study period. CONCLUSIONS AND CLINICAL RELEVANCE: Results suggest that oral administration of cyclosporine at a dosage of 5.0 mg/kg once daily is effective in reducing severity of pruritus and skin lesions in dogs with AD, especially those with nonseasonal disease.  相似文献   

我国玉米螟优势种的研究   总被引：16，自引：1，他引：16       下载免费PDF全文

全国玉米螟综合防治研究协作组 《植物保护学报》1988,15(3):145-152

1977—1984年,通过形态鉴定、生殖隔离试验、性信息素活性反应及其化学成份分析等四种方法,明确我国玉米螟优势种是亚洲玉米螟Ostrinia furnacalis(Guenee),而不是欧洲玉米螟O.nubilalis(Hubner)。亚洲玉米螟主要分布在我国东半壁黑龙江至广东的广大地区,是玉米、谷子、高粱等作物的大害虫。欧洲玉米螟分布于新疆(伊宁),为害玉米,并在内蒙古(呼和浩特)、宁夏(永宁)和河北(张家口、芦台)一带与亚洲玉米螟混生(仍以亚洲玉米螟为主),多寄生于苍耳和大麻。  相似文献   

我国西南岩溶地区发展畜牧业的战略设想   总被引：1，自引：0，他引：1  

Research Group of Sustainable Agricultural Development in Karst Regions of China  Chinese Academy of Engineering 《草业学报》1999,(Z1)

我国西南岩溶地区草地资源丰富 ,有适宜发展饲用植物的生物气候资源 ,有一定的家畜基础和技术储备 ,有社会发展的需求 ,因此有建成畜牧产业带的基础。现阶段虽然起点低 ,但潜力巨大 ,可以发展以林业为主的水土保持畜牧业、农耕地区的畜牧业、景观农业中的畜牧业、城郊畜牧业和山地畜牧业。畜牧业产业化应遵守 5项原则 ,并具备 8个方面的特色 ,可以考虑建立 1个产业中心群 ,2个产业带的设想。最后提出国家设立专项畜牧产业带的发展基金、组建省际协调组织、大力发展每个畜牧产业带的龙头企业和企业集团、建立完善的投资管理系统和技术支持系统等 5条具体建议  相似文献   

高新技术在茶叶加工中的应用   总被引：1，自引：0，他引：1  

任俊银 《蚕桑茶叶通讯》1999,(3):2-5

本文简述了膜分离技术,超临界流体萃取技术,冷杀菌技术及真空冷冻干燥等新技术的基本原理及其在茶叶加工中的应用状况。  相似文献   

控制棉铃虫猖獗危害的区域性综合防治关键技术体系的研究   总被引：2，自引：0，他引：2  

中国农业科学院植物保护研究所棉花害虫研究组 《中国农业科学》1995,28(1):1-7

在跟踪推广应用“六五”以来所形成的综防技术基础上,进一步研究改进关键技术、加强病虫监测预报、组建综防技术体系。在1992、1993年棉铃虫猖獗发生的情况下,于河南省新乡棉花病虫害综防示范区0.67万hm#+2棉田上实施后,有效控制了棉铃虫危害。这套控制棉铃虫猖獗危害综合防治关键技术主要是：研究改进了棉铃虫中期预报方法;提出“一代监测、二代保顶、三代保蕾、四代保铃”为主的防治策略;制定推广适用于不同世代、不同水肥条件的科学防治指标;协调应用多种配套措施保护、利用自然天敌控害;系统监测和治理害虫抗药性;利用棉花种质资源和品种的抗病虫性;诱杀成虫;组建大面积综防技术体系。  相似文献   

太阳能-热泵除湿机-微计算机监控联合干燥系统的研究   总被引：1，自引：2，他引：1  

TRCW课题组 《北京林业大学学报》1991,13(3):29-35

太阳能-热泵除湿机-微计算机监控(TRCW)联合干燥系统中,木材干燥室的供热与湿空气的排湿,由太阳能供热系统和热泵除湿机两者配合起来完成。整个联合干燥系统的工作过程由微机监控系统来实现自动控制。太阳能集热器为平板式空气型,采光面积为75m~2,,热泵除湿干燥机按压缩式制冷循环工作(压缩机功率为3.75kW),以热泵供热的方式供给木材干燥所需的热量,而以制冷除湿方式除去木材蒸发到空气中的水分。联合系统的干燥能力为15～25m~3木材,在1989年4月至1990年7月的实验中,干燥的材种有水曲柳、柞木、榆木、红松、白松等。木材板厚为3～6cm,初含水率40％～60％,终含水率8.5％～15％,年平均干燥能耗每m~3木材为80kW·h及每kg水为0.53kW·h。  相似文献   

白斑狗鱼耗氧率和窒息点研究   总被引：25，自引：1，他引：25  

乔德亮李思发  凌去非殷建国蔡晓琴  李岩平何智杰 《上海水产大学学报》2005,14(2):202-206

白斑狗鱼(Esoxlucius)属鲑形目(Salmoniformes)、狗鱼科(Esocidae)、狗鱼属(Esox),北半球北部亚冷水性大型凶猛淡水鱼类,我国仅产于新疆北部额尔齐斯河流域,如额尔齐斯河、布尔津河、哈巴河等及附属水体。鱼类大多数代谢活动都和氧的利用有关,耗氧率直接或间接地反映新陈代  相似文献   

关联分析及其在植物中的应用     

于海霞  肖静  田纪春  王玮 《广西农业生物科学》2009,(1):187-194

关联分析是新近开始在植物数量性状研究和植物育种中应用的一种分析方法。它以连锁不平衡为基础鉴定某一群体内性状与遗传标记或候选基因间的关系,是对分子育种中QTL分析的补充和提高。本文在介绍连锁不平衡的定义和度量方法的基础上,讨论连锁不平衡程度和群体结构对关联分析的影响,综述了关联分析在植物方面的研究进展,并最后讨论了关联分析在植物数量性状和分子育种研究中可能的应用。  相似文献